Inflammation News and Research

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New Method Analyzes Tooth Enamel Proteins to Gain Insights into Human Health History

A new way of looking at tooth enamel could give scientists a path to deeper understanding of the health of human populations, from the ancient to the modern.

20 Sep 2024

Low Extracellular Sodium Concentrations Can Suppress mRNA Expression in Brain Cells

Brain and mental problems can result from chronic hyponatremia, a disorder marked by low blood salt levels.

19 Sep 2024

New study highlights the medicinal potential of plants consumed by gorillas

In a recent study, researchers examined the antibacterial and antioxidant properties of plants used by western lowland gorillas for self-medication, highlighting the potential of these bioactive compounds for therapeutic applications in human medicine.

19 Sep 2024

CRISPR and Antibodies Offer New Hope for Improving CAR-T Cell Therapy Outcomes

Mayo Clinic researchers mined the molecular foundations of cancer and uncovered a new reason chimeric antigen receptor (CAR-T cell therapy) fails in some patients.

13 Sep 2024

New Research Uncovers Healing Benefits of Pyroptosis

A study by the team of Prof. Kodi Ravichandran (VIB-UGent Center for Inflammation Research) and colleagues found that pyroptosis, a form of programmed cell death traditionally thought to be purely inflammatory, also plays a crucial role in promoting healing and tissue repair.

12 Sep 2024

Study Reveals How Damaged Cells Contribute to Chronic Kidney Disease Progression

A study published in Nature Communications provides new insight into how damaged cells interact within disease-promoting microenvironments following acute kidney injury, or AKI.

6 Sep 2024

Inflammation-Induced Epigenetic Changes Limit Intestinal Stem Cell Regeneration

Researchers from the University of Michigan, Baylor College of Medicine, and other affiliated institutions have found that intestinal stem cells (ISCs) are permanently altered by inflammation in the gut, which limits the cells' capacity to repair the gut even after the inflammation has subsided.

4 Sep 2024

The Molecular Process That Causes MS and Autoimmune Diseases

A human immune system suppressor known as “regulatory T cells” was first identified more than 20 years ago by a research team working in the lab of Yale researcher David Hafler, who was at Harvard at the time.

29 Aug 2024

Cryo-EM Study Sheds Light on HSV Drug Resistance Mechanisms Through Protein Movement

All organisms -; from fungi to mammals -; have the capacity to evolve and adapt to their environments. But viruses are master shapeshifters with an ability to mutate greater than any other organism. As a result, they can evade treatments or acquire resistance to once-effective antiviral medications.

28 Aug 2024

Insights into Hmmr's Role in Cognitive Decline and Lifespan

The authors investigate the physiological functions of Terc-53 by creating transgenic mice that overexpress this noncoding RNA. They observe that Terc-53 overexpression affects normal aging in mammals, contributing to cognitive decline and shortened lifespan.

27 Aug 2024

Study Utilizes Flow Cytometry and Advanced Transcriptomics to Reveal Age-Related Defects in Thymic Regeneration

Research identifies two states of age-associated thymic epithelial cells, linking thymic degeneration to aging and injury, impacting immune system function.

26 Aug 2024

New Human Intestinal Immuno-Organoids Reveal Insights into Immune Cell Dynamics and Cancer Immunotherapy

Research on intestinal immuno-organoids reveals their potential in modeling immune interactions and studying intestinal diseases linked to cancer therapies.

26 Aug 2024

Study Identifies Key Macrophage Subpopulations in MASH Progression and Regression

Formerly known as nonalcoholic steatohepatitis, metabolic dysfunction-associated steatohepatitis (MASH) is an inflammatory disease characterized by liver scarring or fibrosis that progressively impairs liver function.

23 Aug 2024

Ancient Viral Remnants Serve as Accurate Aging Clock

DNA markers linked to retroelements - remaining pieces of ancient viral genetic material - in human genes have been found by researchers at Weill Cornell Medicine and the epigenetics startup TruDiagnostic.

20 Aug 2024

Breakthrough Research Reveals Early Development of Eye Macrophages in Mice

Macrophages, also known as scavenger cells, are part of our immune system. They destroy invading pathogens and are found in the organs and the bloodstream.

20 Aug 2024

New Insights into Cell Communication During Inflammation

Indiana University School of Medicine researchers have made significant progress in understanding how cells communicate during inflammation.

16 Aug 2024

New ProDOL Technique Revolutionizes Protein Counting in Living Cells

Scientists have developed a new way of counting labeled proteins in living cells that could become a standard and valuable tool in the field of biomedical research.

12 Aug 2024

Emerging Treatments and Drug Repositioning for NAFLD and NASH

The current research on drug candidates and molecular targets being clinically tested for the treatment of non-alcoholic steatohepatitis (NASH) and NAFLD.

9 Aug 2024

LINE-1 RNA from Ancient Viruses Promotes Bone Repair

Around half of the human genome is composed of DNA fragments originating from ancient viruses. These "transposable elements" (TEs) are now known to play various roles in modulating gene expression and disease development.

8 Aug 2024

Researchers Uncover Method to Boost Stem Cell Production Using Interferon Gamma

Researchers at the Centre for Genomic Regulation (CRG) have discovered a treatment which accelerates the production and quality of pluripotent stem cells in mice.