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Rising Prevalence of Chronic Rhinosinusitis in Japan: Causes and Implications

Chronic rhinosinusitis (CRS) is an inflammatory condition affecting the nasal cavity and sinuses, which can be categorized into eosinophilic and non-eosinophilic subtypes.

7 Nov 2023

New Atlases Reveal Unprecedented Detail of the Human Brain

In two concurrent projects, scientists at the Karolinska Institutet have played a significant role in producing the most extensive atlases of human brain cells to date.

13 Oct 2023

Increased Pain Sensitivity and Neanderthal Gene Variants

According to a recent study co-led by UCL researchers, those who contain three gene variations acquired from Neanderthals are more susceptible to specific types of pain.

11 Oct 2023

Genes may be Responsible for Third of Complex Regional Pain Syndrome Cases

But the condition is less common in men, even though they are more likely to have the 4 genetic variations implicated in heightened risk, suggesting that there may be sex specific causes, say the researchers.

11 Oct 2023

Scientists Gain Insights into Biophysical Properties of Neurons with New Workflow

Biophysically detailed neuronal models provide a unique window into the workings of individual neurons.

5 Oct 2023

Study: Swimming and Tubing Can Alter Stream Chemistry and Microbiology

With Labor Day approaching, many people are preparing to go tubing and swimming at local streams and rivers.

19 Sep 2023

Sensory Neurons Develop Customized Nerve Endings Based on Cues From the Skin, Finds Study

Nerve cells that sense touch grow the appropriate endings for hairy or hairless skin based on cues from the skin itself, rather than through predetermined programming, according to research led by Harvard Medical School scientists and published Aug. 21 in Developmental Cell.

23 Aug 2023

Newly Developed Antibody Therapy to Have Benefits Over Existing Opioid-Overdose Treatments

An antibody in single-chain fragment variable (scFv) format that binds to the powerful opioid carfentanil was shown to reverse signs of carfentanil overdose in preclinical tests conducted by scientists at Scripps Research.

11 Aug 2023

Study Shows How Sensory Neurons Control Gastrointestinal Tracts

Gastrointestinal and digestive issues impact roughly 3 million people across the United States alone, and that number is growing.

4 Aug 2023

Researchers Pinpoint the Genes that Shape the Skeletons

Using artificial intelligence to analyze tens of thousands of X-ray images and genetic sequences, researchers from The University of Texas at Austin and New York Genome Center have been able to pinpoint the genes that shape our skeletons, from the width of our shoulders to the length of our legs.

21 Jul 2023

Study Provides More Treatment Options for Severe COVID-19

Two anti-inflammatory drugs, abatacept and infliximab, reduced deaths among patients hospitalized with severe COVID-19, according to a national study led by Washington University School of Medicine in St. Louis.

11 Jul 2023

How the Disturbed Recycling Chain of Endoplasmic Reticulum Causes Neurodegenerative Diseases

Our cells are crisscrossed by a system of membrane tubes and pockets called the endoplasmic reticulum (ER). It is crucial for the production of biomolecules and is continuously built up and degraded.

29 May 2023

Research Uncovers the Biology Underpinning a Rare Genetic Mutation Linked to Painlessness

The biology underpinning a rare genetic mutation that allows its carrier to live virtually pain-free, heal more rapidly and experience reduced anxiety and fear, has been uncovered by new research from UCL.

24 May 2023

Altered Anti-Nausea Drug can Penetrate Cells and Provide Sustained Pain Relief

Altering the chemical properties of an anti-nausea drug enables it to enter an interior compartment of the cell and provide long-lasting pain relief, according to a new study led by researchers at NYU College of Dentistry's Pain Research Center.

23 May 2023

Eliminating or Blocking the Tiam1 Gene Prevents, Reverses Chronic Neuropathic Pain

Neuropathy is a type of chronic pain triggered by nerve injury or certain diseases. It affects millions of people worldwide, significantly deteriorating their quality of life.

5 May 2023

Analyzing the Complex Sequence of Events Involved in Beta-Arrestin Interactions

Proteins that work like air traffic controllers, controlling the flow of signals in and out of human cells, have been examined in unparalleled detail for the first time using modern microscope techniques.

5 May 2023

STING-seq Discovers Causal Variants and Genetic Mechanisms for Blood Cell Traits

A major challenge in human genetics is understanding which parts of the genome drive specific traits or contribute to disease risk. This challenge is even greater for genetic variants found in the 98% of the genome that does not encode proteins.

5 May 2023

New CAR T Strategy Offers a Dual-Targeting Mechanism to Fight Bone Metastatic Prostate Cancer

Prostate cancer frequently metastasizes to the bone and is incurable. Moffitt Cancer Center researchers are working to identify new treatment options for this subset of patients.

4 May 2023

Mind-Body Connection is More Than Just an Abstraction

Calm body, calm mind, say the practitioners of mindfulness. A new study by researchers at Washington University School of Medicine in St. Louis indicates that the idea that the body and mind are inextricably intertwined is more than just an abstraction.

20 Apr 2023

Understanding the Functioning of Opioid Receptors at Unprecedented Spatial Resolution

The human body naturally produces opioid-like substances, such as endorphins, which block the perception of pain and increase the feeling of well-being.

20 Apr 2023

Pain News and Research

Rising Prevalence of Chronic Rhinosinusitis in Japan: Causes and Implications

New Atlases Reveal Unprecedented Detail of the Human Brain

Increased Pain Sensitivity and Neanderthal Gene Variants

Genes may be Responsible for Third of Complex Regional Pain Syndrome Cases

Scientists Gain Insights into Biophysical Properties of Neurons with New Workflow

Study: Swimming and Tubing Can Alter Stream Chemistry and Microbiology

Sensory Neurons Develop Customized Nerve Endings Based on Cues From the Skin, Finds Study

Newly Developed Antibody Therapy to Have Benefits Over Existing Opioid-Overdose Treatments

Study Shows How Sensory Neurons Control Gastrointestinal Tracts

Researchers Pinpoint the Genes that Shape the Skeletons

Study Provides More Treatment Options for Severe COVID-19

How the Disturbed Recycling Chain of Endoplasmic Reticulum Causes Neurodegenerative Diseases

Research Uncovers the Biology Underpinning a Rare Genetic Mutation Linked to Painlessness

Altered Anti-Nausea Drug can Penetrate Cells and Provide Sustained Pain Relief

Eliminating or Blocking the Tiam1 Gene Prevents, Reverses Chronic Neuropathic Pain

Analyzing the Complex Sequence of Events Involved in Beta-Arrestin Interactions

STING-seq Discovers Causal Variants and Genetic Mechanisms for Blood Cell Traits

New CAR T Strategy Offers a Dual-Targeting Mechanism to Fight Bone Metastatic Prostate Cancer

Mind-Body Connection is More Than Just an Abstraction

Understanding the Functioning of Opioid Receptors at Unprecedented Spatial Resolution

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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