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Study identifies a novel role for regulatory protein Bach1 in Parkinson's disease

Parkinson's disease (PD) is the most common neurodegenerative movement disorder, afflicting more than 10 million people worldwide and more than one million Americans. While there is no cure for PD, current therapies focus on treating motor symptoms and fail to reverse, or even address, the underlying neurological damage.

26 Oct 2021

Genetic biomarker test could help personalize therapy for men with high-risk prostate cancer

A new meta-analysis finds that a genetic biomarker test accurately predicts how men with high-risk prostate cancer will respond to treatment with radiation and hormone therapy.

26 Oct 2021

Cell-free DNA employed to identify measurable residual disease

Researchers demonstrated that cell-free DNA from CSF could be employed to examine MRD in children treated for the brain tumor medulloblastoma.

25 Oct 2021

Scientists use DNA to create what may be the world's tiniest ruler for measuring proteins

As scientists have probed the mysteries of life down to smaller and smaller scales, they have invented tools to help them understand what they observe.

22 Oct 2021

Research opens new therapeutic perspectives for treatment of skin fibrosis

Collagen, the main component of the skin's extracellular matrix, can cause a pathological condition if it is in excess. Applying an electric field to the skin affects collagen pathways, temporarily reducing collagen production and increasing its degradation.

22 Oct 2021

Targeted drug shows promise against brain metastases from kidney cancer

A targeted drug has shown promising activity against brain metastases resulting from kidney cancer, achieving a 50 percent response rate, and supporting further studies of the drug in this patient group whose poor prognosis has created a significant unmet need.

22 Oct 2021

'Switching on' Sight using Gene Therapy

AZoLifeSciences speaks to Dr. Raymond Wong about his latest research into eye health and we could potentially 'switch on' sight using gene therapy.

20 Oct 2021

Study identifies highly potent monoclonal antibody against all SARS-CoV-2 variants

Researchers identified a greatly potent monoclonal antibody that aims at the spike protein of SARS-CoV-2.

19 Oct 2021

AI-powered tool rapidly identifies genetic causes of rare disorders with high accuracy

An artificial intelligence (AI)-based technology rapidly diagnoses rare disorders in critically ill children with high accuracy, according to a report by scientists from University of Utah Health and Fabric Genomics, collaborators on a study led by Rady Children's Hospital in San Diego. The benchmark finding, published in Genomic Medicine, foreshadows the next phase of medicine, where technology helps clinicians quickly determine the root cause of disease so they can give patients the right treatment sooner.

From The University of Utah 18 Oct 2021

Type A immunoglobulins play a key role in keeping the intestinal flora in balance

The bacteria living in the intestine consist of some 500 to 1000 different species. They make up what is known as the intestinal flora, which plays a key role in digestion and prevents infections.

15 Oct 2021

Scientists show how skin T cells can damage other organs in stem cell transplant patients

More than 40,000 allogeneic hematopoietic stem cell transplants are carried out worldwide every year, mostly for patients suffering from leukemia or other diseases of the hematopoietic system.

15 Oct 2021

Study reveals gene responsible for food-dependent form of Cushing's Syndrome

A team of scientists in Montreal and Paris has succeeded in identifying the gene responsible for the development of a food-dependent form of Cushing's Syndrome, a rare disease affecting both adrenal glands.

15 Oct 2021

Research identifies genes that influence the outcomes of physical activity

Recent research identified that genes carry out a vital role in how human bodies respond to exercise. The study has also pinpointed various genes that influence the outcomes of different types of physical activity.

15 Oct 2021

Researchers improve understanding of molecular mechanisms underlying stomach’s acid pump

Nagoya University researchers and colleagues have improved understanding of the molecular mechanisms of a key protein that makes the stomach acidic. Their findings, published in the journal Nature Communications, could lead to better drugs for stomach ulcers and shed light on the functions of similar proteins across the human body.

15 Oct 2021

Study: Sex matters when it comes to susceptibility to infections and other health conditions

A University of Alberta-led study shows that when it comes to susceptibility to infections and other health conditions, sex matters.

13 Oct 2021

Loss of mitochondrial respiration alters mechanical properties of the cartilage

A group of researchers headed by Professor Dr Bent Brachvogel, Head of Experimental Neonatology at the Faculty of Medicine and University Hospital Cologne, have identified regulatory mechanisms of tissue organization which were earlier unknown.

8 Oct 2021

Experts create “living medicine” to combat biofilms on medical implants

Scientists have developed the first “living medicine” to treat antibiotic-resistant bacteria thriving on medical implants’ surfaces.

8 Oct 2021

Clinical efficacy of CAR-T cells depends on chemical modifications, says study

One in five cancers affects lymph nodes and blood cells resulting in lymphomas and leukemias, respectively.

7 Oct 2021

Scientists identify novel nairovirus associated with acute febrile illness in Japan

A previously unknown virus that can infect humans and cause disease has been identified by scientists in Japan.

5 Oct 2021

Diagnostic value of SARS-CoV-2 specific T cell immune responses may be limited

Can T-cell tests be used to determine whether people have had COVID-19? Scientists at Uppsala University and Karolinska Institutet have jointly analysed this issue under the aegis of the COMMUNITY study at Danderyd Hospital. Their study is published in the scientific journal PLOS ONE.

5 Oct 2021

Hospital News and Research

Study identifies a novel role for regulatory protein Bach1 in Parkinson's disease

Genetic biomarker test could help personalize therapy for men with high-risk prostate cancer

Cell-free DNA employed to identify measurable residual disease

Scientists use DNA to create what may be the world's tiniest ruler for measuring proteins

Research opens new therapeutic perspectives for treatment of skin fibrosis

Targeted drug shows promise against brain metastases from kidney cancer

'Switching on' Sight using Gene Therapy

Study identifies highly potent monoclonal antibody against all SARS-CoV-2 variants

AI-powered tool rapidly identifies genetic causes of rare disorders with high accuracy

Type A immunoglobulins play a key role in keeping the intestinal flora in balance

Scientists show how skin T cells can damage other organs in stem cell transplant patients

Study reveals gene responsible for food-dependent form of Cushing's Syndrome

Research identifies genes that influence the outcomes of physical activity

Researchers improve understanding of molecular mechanisms underlying stomach’s acid pump

Study: Sex matters when it comes to susceptibility to infections and other health conditions

Loss of mitochondrial respiration alters mechanical properties of the cartilage

Experts create “living medicine” to combat biofilms on medical implants

Clinical efficacy of CAR-T cells depends on chemical modifications, says study

Scientists identify novel nairovirus associated with acute febrile illness in Japan

Diagnostic value of SARS-CoV-2 specific T cell immune responses may be limited

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