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UC Davis Health tests new antibody combination as potential treatment for COVID-19

Timothy Albertson, chair of internal medicine and specialist in pulmonary and critical care, is leading efforts at UC Davis Health to test a new antibody cocktail (REGN-COV2) as a prevention and treatment for COVID-19.

From The University of California, Davis 21 Jul 2020

Researchers find a way to prevent SARS-CoV-2 virus from binding to cells

On July 1, the Texas A&M Engineering Experiment Station's (TEES) National Center for Therapeutics Manufacturing (NCTM) received funding from the National Institute for Innovation in Manufacturing Biopharmaceuticals (NIIMBL) to help find a way to prevent the SARS-CoV-2 virus from binding to cells, protecting people from future infections.

20 Jul 2020

Blood vessels communicate with peripheral neurons to regulate neuronal differentiation

Researchers at Pompeu Fabra University have shown for the first time that blood vessels communicate with neurons in the peripheral nervous system, regulating their proliferation and differentiation.

17 Jul 2020

Substances that target oxytocin receptors can help treat various diseases

Oxytocin is the so-called “cuddle hormone” or “love hormone” that plays a role in strengthening the relationship between the mother and child and controlling social bonding.

17 Jul 2020

Study shows how breast cancer cells escape the immune system

Scientists have explained a new method that clearly shows how a crucial player in the body’s immune system is destroyed by breast cancer cells.

17 Jul 2020

New, promising CAR T cell therapy results in exceptional patient recovery

In a clinical trial evaluating a novel immunotherapy option for cancer treatment, a child with rhabdomyosarcoma, a form of muscle cancer, that had spread to the bone marrow, showed no detectable cancer following treatment with chimeric antigen receptor (CAR) T cells that were engineered to target the HER2 protein on the surface of cancerthe cells.

16 Jul 2020

Imaging mass spectrometry identifies tumor markers for head and neck squamous cell carcinoma

Volume 11, Issue 28 of Oncotarget features "Lipid and protein tumor markers for head and neck squamous cell carcinoma identified by imaging mass spectrometry" by Schmidt et. al. which reported that the authors used MALDI imaging mass spectrometry and immunohistochemistry to seek tumor-specific expression of proteins and lipids in HNSCC samples.

15 Jul 2020

New study can help develop novel drugs for prostate cancer

The androgen receptor is considered the main driver of the growth and initiation of prostate cancer, which is known to be the second-leading cause of death in men.

15 Jul 2020

High amount of SARS-Cov-2 receptor is present in patients with pre-existing cardiac conditions

Nearly 20% of all COVID-19-associated deaths are from cardiac complications, yet the mechanisms from which these complications arise have remained a topic of debate in the cardiology community.

15 Jul 2020

PET radiotracer is safe and effective for imaging malignant brain tumors

A first-in-human study presented at the Society of Nuclear Medicine and Molecular Imaging 2020 Annual Meeting has demonstrated the safety, favorable pharmacokinetic and dosimetry profile of 64Cu-EBRGD, a new, relatively long-lived PET tracer, in patients with glioblastomas.

14 Jul 2020

The immune system can play a key role in improving recovery from heart attacks

International research collaboration to pioneer the field of immuno-cardiology and investigate ways to harness the power of the immune system to improve recovery from heart attacks will be led at the Perelman School of Medicine at the University of Pennsylvania by Jonathan Epstein, MD, executive vice dean, chief scientific officer and the William Wikoff Smith Professor of Cardiovascular Research.

14 Jul 2020

Analysis of nearly 300 new SARS-CoV-2 antibodies reveals a common feature

An analysis of nearly 300 recently identified human SARS-CoV-2 antibodies uncovered a gene frequently used in antibodies that most effectively target the virus. The results contribute to growing structural insight that will be needed for successful vaccine development against SARS-CoV-2.

14 Jul 2020

Less addictive opioid may have the ability to slow progression of osteoarthritis

A novel preclinical study by Keck Medicine of USC researchers, published in Arthritis & Rheumatology, reveals that a potential new opioid medication may have the ability to slow the progression of osteoarthritis while being less addictive than commonly prescribed opioid drugs.

14 Jul 2020

Common molecular feature in SARS-CoV-2 neutralizing antibodies discovered

A team led by scientists at Scripps Research has discovered a common molecular feature found in many of the human antibodies that neutralize SARS-CoV-2, the coronavirus that causes COVID-19.

14 Jul 2020

A mapping method to study different cell type changes in developing mouse brains

Penn State researchers have developed a new method for studying key moments in brain development. Yongsoo Kim, assistant professor of neural and behavioral sciences at Penn State College of Medicine, is using the method to understand how oxytocin receptor expression changes in normally developing mice and mouse models of autism spectrum disorder.

14 Jul 2020

Single dose of tocilizumab improves survival in critically ill COVID-19 patients

Critically ill COVID-19 patients who received a single dose of a drug that calms an overreacting immune system were 45% less likely to die overall, and more likely to be out of the hospital or off a ventilator one month after treatment, compared with those who didn't receive the drug, according to a new study by a team from the University of Michigan.

14 Jul 2020

Receptor News and Research

UC Davis Health tests new antibody combination as potential treatment for COVID-19

Researchers find a way to prevent SARS-CoV-2 virus from binding to cells

Blood vessels communicate with peripheral neurons to regulate neuronal differentiation

Substances that target oxytocin receptors can help treat various diseases

Study shows how breast cancer cells escape the immune system

New, promising CAR T cell therapy results in exceptional patient recovery

Imaging mass spectrometry identifies tumor markers for head and neck squamous cell carcinoma

New study can help develop novel drugs for prostate cancer

High amount of SARS-Cov-2 receptor is present in patients with pre-existing cardiac conditions

PET radiotracer is safe and effective for imaging malignant brain tumors

The immune system can play a key role in improving recovery from heart attacks

Analysis of nearly 300 new SARS-CoV-2 antibodies reveals a common feature

Less addictive opioid may have the ability to slow progression of osteoarthritis

Common molecular feature in SARS-CoV-2 neutralizing antibodies discovered

A mapping method to study different cell type changes in developing mouse brains

Single dose of tocilizumab improves survival in critically ill COVID-19 patients

Altimmune reports positive results on intranasal COVID-19 vaccine candidate

Study identifies brain cells that control sugar intake and cravings

Study reveals the key role of adiponectin in muscle regeneration

Study identifies a new target for cancer treatment

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