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Specific immune mechanism in COVID-19 patients triggers inflammatory process

Researchers at the University of São Paulo (USP) in Brazil have demonstrated for the first time that in COVID-19 patients an immune mechanism known as the inflammasome participates in activation of the inflammatory process that can damage several organs and even lead to death.

3 Dec 2020

Researchers determine role of NLRP1 protein in detecting the common cold virus

The role of a protein in detecting the common cold virus and kickstarting an immune response to fight infection has been uncovered by a team of scientists from Nanyang Technological University, Singapore (NTU Singapore), the Agency for Science, Technology and Research (A*STAR) and the National University of Singapore.

From Nanyang Technological University Singapore (NTU Singapore) 3 Dec 2020

Study confirms that telomere shortening helps prevent cancer in humans

As time goes by, the tips of your chromosomes--called telomeres--become shorter. This process has long been viewed as an unwanted side-effect of aging, but a recent study shows it is in fact good for you.

2 Dec 2020

Researchers identify chemical compounds that could block key enzyme in SARS-CoV-2

According to a new study, chemical compounds found in dark chocolate can inhibit the function of a specific enzyme, or protease, in the SARS-CoV-2 virus.

1 Dec 2020

New study refutes a major cellular process in bacteria

Despite explanations in textbooks, a new study has discovered and elucidated a cellular process that has continued to remain a mystery for researchers.

30 Nov 2020

Research reveals a gene responsible for anthraquinone synthesis in plants

Anthraquinones are a class of naturally occurring compounds prized for their medicinal properties, as well as for other applications, including ecologically friendly dyes. Despite wide interest, the mechanism by which plants produce them has remained shrouded in mystery until now.

25 Nov 2020

Novel targeted therapy blocks critical metabolic pathways in cancer cells

Scientists have designed a new targeted therapy, known as POMHEX, which inhibits vital metabolic pathways in tumor cells containing specific genetic defects.

24 Nov 2020

Researchers reveal new details of crucial steps involved in the maturation of ribosomes

Ribosomes synthesize all the proteins in cells. Studies mainly done on yeast have revealed much about how ribosomes are put together, but an Ludwig-Maximilians-Universitaet (LMU) in Munich team now reports that ribosome assembly in human cells requires factors that have no counterparts in simpler model organisms.

23 Nov 2020

Researchers prepare biocompatible protocells to pump up blood vessels

An international team comprising researchers from the University of Bristol, and Hunan and Central South Universities in China, have prepared biocompatible protocells.

23 Nov 2020

Gaining new insights into bacterial pneumonia

Jacqueline Kimmey speaks to AZoLifeSciences about her research into bacterial pneumonia and the genes that drive its spread from the lungs into the blood.

From University of California Santa Cruz 23 Nov 2020

Novel DNA-based nanogel for targeted delivery of chemotherapeutics

Current chemotherapy regimens slow cancer progression and save lives, but these powerful drugs affect both healthy and cancerous cells.

19 Nov 2020

Study identifies molecular mutation more common in African Americans with late-onset Alzheimer’s

Scientists have identified a molecular mechanism that leads to a “traffic jam” of enzymes, resulting in the accumulation of amyloid-beta.

19 Nov 2020

Study shows CRISPR/Cas9 system can effectively treat metastatic cancers

Researchers have shown that the advanced CRISPR/Cas9 system is extremely effective in curing metastatic cancers.

19 Nov 2020

Study finds that cannabidiol induces the expression of heme oxygenase 1 in skin cells

At present, cannabidiol has found considerable use not just in the world of cosmetics but also in nutrition and pharmaceutics due to its therapeutic potential.

17 Nov 2020

Clostridium bacteria can help convert waste gas into valuable compounds

Several branches of industry discharge waste gases that contain mostly carbon dioxide and carbon monoxide.

17 Nov 2020

Several hepatitis C drugs can inhibit the SARS-CoV-2 main protease

Scientists have determined that drugs meant for treating hepatitis C can block SARS-CoV-2 main protease, which allows reproduction in the novel coronavirus.

17 Nov 2020

New research uncovers vital link in complex biochemical pathway for saponin synthesis

Many plants, including legumes, make naturally occurring chemicals called saponins. For example, the medicinal plant licorice produces the saponin glycyrrhizin, a potent natural sweetener that also has antiviral and other pharmacological activity. Soyasaponins, found in soybeans, have anticarcinogenic and antioxidant properties.

From Osaka University 17 Nov 2020