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3D structure of a major protein complex in cilia revealed

Researchers at St. Jude Children’s Research Hospital have solved the 3D structure of an important protein complex in cilia, which are signaling appendages found on cells. The structure was pictured at the highest resolution available at the time.

15 Feb 2023

Identifying mechanisms that may promote hair cell regeneration in mammals

Taking a bite of an apple is considered a healthy choice. But have you ever thought about putting in earplugs before your favorite band takes the stage?

14 Feb 2023

Cochlear organoids provide a platform to understand sensorineural hearing loss

Disabling hearing loss affects one in every ten people and up to 25% of people over 60, according to the World Health Organization, and can have both genetic and environmental causes such as infections and noise exposure.

1 Feb 2023

Investigating the molecular mechanisms that govern cilia force sensing

Although the human body is superficially symmetric along the left–right axis, most internal organs, including the heart, lungs, liver, stomach, and brain, have noteworthy left–right asymmetries in their structure and placement.

6 Jan 2023

Ultrafast, highly sensitive detection of proteins using simple laser irradiation

Protein detection based on antigen–antibody reaction is vital in early diagnosis of a wide range of diseases. How to effectively detect proteins, however, has frequently bedeviled researchers.

4 Jan 2023

The influence of genes and small molecules on personal disease risk

Each individual has a unique chemical fingerprint. Small molecules in the blood, like fats or sugars, have a significant impact on how the human body responds to stress, which diseases people are predisposed to, and how serious an illness will be.

23 Nov 2022

Investigating the direct effect of mutation on sperm behavior

A team of researchers discovered that the activity of sperm cells is attributable in part to the individual DNA make-up of these cells, rather than just male genetics.

From New York University (NYU) 16 Nov 2022

DNA-based nanotransporters could improve treatment of cancers, other diseases

A team of Canadian researchers from Université de Montréal has designed and validated a new class of drug transporters made of DNA that are 20,000 times smaller than a human hair and that could improve how cancers and other diseases are treated.

2 Nov 2022

Discovering H2O2 sensing capacity in plants that control immunity

All aerobic organisms produce the molecule hydrogen peroxide (H2O2). When present in low concentrations, it acts as a crucial secondary signal to control a variety of biological processes, including but not limited to plant-microbe interactions, abiotic stress tolerance, pollen tube growth, root hair formation, leaf cell expansion, and Casparian strip formation.

20 Oct 2022

Native 3D structure of the ciliary base witnessed for the first time

Because flaws in the cilia transport system can result in, for example, blindness or cystic kidneys, findings reported in Science offer new understandings of the molecular basis for different diseases.

20 Sep 2022

Unique combination of transcription factors trigger cell regeneration in zebrafish

Scientists at the National Institutes of Health have identified a particular protein network required for cell regeneration to restore hearing in zebrafish.

From National Human Genome Research Institute (NHGRI) 15 Sep 2022

Nanomaterials offer a rich avenue to achieve broad-spectrum bioactivities

Cancer treatment is a lengthy procedure because surviving cancer cells frequently transform into aggressive versions that are no longer curable.

From The Max Planck Institute 9 Sep 2022

Researchers investigate the effects of transient oxygen starvation on protein folding in plants

Protein molecules require a defined shape in order to function. When they are created, their building blocks are therefore linked together in a very specific way.

13 Jul 2022

Researchers develop first biohybrid model of human ventricles with helically aligned beating cardiac cells

Heart disease -; the leading cause of death in the U.S. -; is so deadly in part because the heart, unlike other organs, cannot repair itself after injury.

11 Jul 2022

Researchers analyze ultra-thin layer of lipids in gecko feet, likely to serve as their grip factor

Geckos are known for having sturdy feet that enable them to easily scale vertical surfaces. Millions of microscopic, hair-like structures on their toes provide them with this apparent superpower.

From National Institute of Standards and Technology (NIST) 8 Jul 2022

Producing food without sunlight through artificial photosynthesis

Photosynthesis is the process that enables plants to take sunlight and carbon dioxide and convert it into chemical energy to grow.

29 Jun 2022

Protecting foods with antimicrobial, plant-based food wrap

Aiming to produce environmentally friendly alternatives to plastic food wrap and containers, a Rutgers scientist has developed a biodegradable, plant-based coating that can be sprayed on foods, guarding against pathogenic and spoilage microorganisms and transportation damage.

From Rutgers University 21 Jun 2022

Robotic finger covered with living skin tissue can heal itself

Researchers from the University of Tokyo pool knowledge of robotics and tissue culturing to create a controllable robotic finger covered with living skin tissue.

20 Jun 2022

Scientists develop tiny probe for minimally invasive interfacing with neural circuits

Researchers at the University of California San Diego and the Salk Institute for Biological Studies have developed a tiny neural probe that can be implanted for longer time periods to record and stimulate neural activity, while minimizing injury to the surrounding tissue.

From UC San Diego 10 Jun 2022

Researchers use new technique to examine the composition of cell walls from young poplar trees

To optimize biomaterials for reliable, cost-effective paper production, building construction, and biofuel development, researchers often study the structure of plant cells using techniques such as freezing plant samples or placing them in a vacuum.

8 Jun 2022