Prostate Cancer News and Research

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Prostate cancer is the most common non-skin cancer in the United States and the third most common cancer worldwide. More than 1 million men in the United States have prostate cancer and it is the second leading cause of cancer death amongst men after lung cancer. In 2009, an estimated 192,280 new cases are expected to be diagnosed and approximately 27,360 men are expected to die from the disease. Castration-resistant prostate cancer (CRPC) is defined as prostate cancer that continues to grow despite all standard-of-care hormonal (anti-androgen) therapies. Patients with castration-resistant (also known as hormone-refractory) prostate cancer have few treatment options and a poor prognosis.

Researchers study how people at risk for cancer react to feedback of genetic findings

Researchers at the Estonian Genome Center at the University of Tartu studied how people at high risk for breast, ovarian or prostate cancer respond to the feedback of genetic findings.

26 Nov 2020

Researchers use metal-organic frameworks to target prostate cancer cells

Scientists have used metal-organic frameworks to effectively deliver the CRISPR/Cas9 genetic snipping tool into human cancer cells.

23 Nov 2020

Genetic signature in localized prostate cancer can predict likelihood of tumor metastases

Researchers have identified a genetic signature in localized prostate cancer that can predict whether the cancer is likely to spread, or metastasize, early in the course of the disease and whether it will respond to anti-androgen therapy, a common treatment for advanced disease.

11 Nov 2020

Unrelated mutations can lead to false positive results in men with advanced prostate cancer

Unrelated mutations, when present in the blood, can lead to false positive results in men with advanced prostate cancer who are undergoing liquid biopsies.

6 Nov 2020

Study shows how cancer remodels human chromosomes for its own purposes

Scientists have shown that cancer rebuilds the architecture of human chromosomes, which allows the disease to take hold and spread.

28 Oct 2020

New research shows ultrasound treatment can destroy cancer cells without surgery

Focusing ultrasound energy on a target site in the body to generate heat can burn and destroy the tissue in the site without a surgical procedure.

27 Oct 2020

Increased weight is causally protective for breast and prostate cancer

Although a recent campaign by Cancer Research UK emphasized obesity as a risk factor for cancer on par with smoking, the scientific literature on the relationship between increased weight and cancer risk is not so clear.

27 Oct 2020

Genomic differences can help develop more personalized treatments for African American men

Prostate cancer is the most common type of cancer among American men after skin cancer, but the disease does not affect all races equally.

22 Oct 2020

Rutgers researchers discover gene markers linked to metastatic prostate cancer

Rutgers researchers have discovered human gene markers that work together to cause metastatic prostate cancer - cancer that spreads beyond the prostate.

From Rutgers University 20 Oct 2020

Study shows thymoquinone compound selectively kills prostate cancer cells

According to a new study reported in the Oncogene journal, the thymoquinone (TQ) compound selectively destroys prostate cancer cells at advanced phases.

9 Oct 2020

Prostate cancer screening tool leads to fewer biopsies and potential savings

Multiparametric magnetic resonance imaging of the prostate (mpMRIp) is a promising tool for diagnosing prostate cancer, and prior to its availability, detection relied on clinical exams and prostate specific antigen screening.

8 Oct 2020

MIT engineers develop a method to turn off specific genes in bone marrow cells

Using specialized nanoparticles, MIT engineers have developed a way to turn off specific genes in cells of the bone marrow, which play an important role in producing blood cells.

From Massachusetts Institute of Technology (MIT) 6 Oct 2020

Gut bacteria may play a role in the treatment of prostate cancer

New research shows how the gut microbiome communicates with an oral drug in prostate cancer patients.

30 Sep 2020

Study shows how PIM kinases enhance the motility of cancer cells

PIM kinases are essentially enzymes that support the metastatic growth and proliferation of tumor cells.

20 Aug 2020

Detecting rare circulating tumor cells

Metastasis - the development of tumor growth at a secondary site - is responsible for the majority of cancer-related deaths.

4 Aug 2020

A novel approach to identify cancer targets using 'synthetic lethality'

With advances in genome sequencing, cancer treatments have increasingly sought to leverage the idea of "synthetic lethality," exploiting cancer-specific genetic defects to identify targets that are uniquely essential to the survival of cancer cells.

28 Jul 2020

Study shows how cancer develops resistance to chemotherapy

Cancer's knack for developing resistance to chemotherapy has long been a major obstacle to achieving lasting remissions or cures. While tumors may shrink soon after chemotherapy, many times they eventually grow back.

24 Jul 2020

Newly discovered protein could be an important target to prevent prostate cancer metastases

Researchers from Boston University School of Medicine (BUSM) have discovered that the protein BRD4 could be an important new target to prevent castration-resistant prostate cancer metastases.

21 Jul 2020

Study shows genetic factors may influence the susceptibility to COVID-19

A new Cleveland Clinic study has identified genetic factors that may influence susceptibility to COVID-19. Published today in BMC Medicine, the study findings could guide personalized treatment for COVID-19.

16 Jul 2020

New study can help develop novel drugs for prostate cancer

The androgen receptor is considered the main driver of the growth and initiation of prostate cancer, which is known to be the second-leading cause of death in men.

15 Jul 2020