Rheumatoid Arthritis News and Research

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Rheumatoid arthritis (RA) is a chronic disease of the joints that can cause a disabling degree of pain and significantly interfere with an individual’s day-to-day living.

Novel molecule shown to have potential therapeutic effects for arthritis

Arthritis affects almost 2% of the world's population, or some 150 million people, and currently, there is no completely effective treatment for this chronic disease. A new molecule developed in the laboratory has been shown to have potential therapeutic effects.

12 Aug 2020

Newly discovered biomarkers predict response to immunotherapy in Type 1 diabetes

Scientists at UCL have discovered new biomarkers, which may identify those people with Type 1 diabetes who would benefit from the immunotherapy drug Abatacept, a finding which could eventually help thousands manage the disease more effectively.

From University College London 4 Aug 2020

Human genome may explain the neonatal origins of immune and inflammatory diseases

A study published in the journal Nature Communications has pinpointed a number of areas of the human genome that may help explain the neonatal origins of chronic immune and inflammatory diseases of later life, including type 1 diabetes, rheumatoid arthritis and coeliac disease.

29 Jul 2020

uEXPLORER TB-PET/CT scanner captures complete picture of systemic inflammatory arthritis

For the first time, physicians can examine the systemic burden of inflammatory arthritis simultaneously across all joints and organ systems, using the high-sensitivity, high-resolution uEXPLORER total-body positron emission tomography/computed tomography (TB-PET/CT) scanner.

14 Jul 2020

Single dose of tocilizumab improves survival in critically ill COVID-19 patients

Critically ill COVID-19 patients who received a single dose of a drug that calms an overreacting immune system were 45% less likely to die overall, and more likely to be out of the hospital or off a ventilator one month after treatment, compared with those who didn't receive the drug, according to a new study by a team from the University of Michigan.

14 Jul 2020

Salk researchers discover genetic 'dial' to fine-tune the immune response

The human immune system is a finely-tuned machine, balancing when to release a cellular army to deal with pathogens, with when to rein in that army, stopping an onslaught from attacking the body itself.

8 Jul 2020

Study highlights the role of hematopoietic immune cells in gene regulation

More often, the human body is viewed as a “machine” containing specialized components: immune cells protect against pathogens, organs contribute physiological functions, and soft tissue and bones give structure.

6 Jul 2020

Females rely on anti-inflammatory T cells for blood pressure control

In the face of a multipronged front to drive blood pressure up, including a high-salt diet, females are better able to keep their pressure down by increasing levels of a T cell that selectively dials back inflammation, scientists say.

23 Jun 2020

New study shows how a protein works as 'master regulator' in the immune system

Scientists at the La Jolla Institute for Immunology have discovered a potential new way to better fight a range of infectious diseases, cancers and even autoimmune diseases.

22 Jun 2020

Study reveals the role of Cpeb4 protein involved in bone and joint diseases

Osteoclasts are bone-dissolving cells that are extracted from a type of immune cell referred to as macrophages which are required for the maintenance of bones.

10 Jun 2020

Understanding protein-coding gene's role in IBD

A protein-coding gene associated with autoimmune diseases such as Crohn's disease and ulcerative colitis, collectively referred to as inflammatory bowel disease, or IBD, will be the focus of new research in the School of Medicine at the University of California, Riverside.

9 Jun 2020

mTOR gene in GvHD patients regulates cell growth and cell survival

Mutations that occur in white blood cells can play a major role in abnormal immune profile following hematopoietic stem cell transplantation.

11 May 2020

MSC‐induced Treg population can yield abundant replacement for naturally occurring T-cells

A new study released today in STEM CELLS suggests for the first time that regulatory T-cells (Treg) induced by mesenchymal stromal cells can yield an abundant replacement for naturally occurring T-cells, which are vital in protecting the body from infection.

30 Apr 2020

'Backpacks' Boost Immune Cells' Ability To Kill Cancer

Macrophages are immune cells that patrol the body looking for potential threats like viruses, bacteria, and cancer cells, and engulf and destroy them.

30 Apr 2020

Experience Matters For Immune Cells

The discovery that immune T cells have a spectrum of responsiveness could shed light on how our immune system responds to infections and cancer.

17 Apr 2020

Improving drug targets for asthma and rheumatoid arthritis

Researchers have found that immune T cells exhibit a range of responsiveness. This finding could offer insights into how the immune system of humans responds to infections and cancer, and what goes wrong in immune diseases.

16 Apr 2020

Research provides new insights into building blocks of gum disease

Porphyromonas gingivalis is a major bacterial pathogen which leads to periodontitis also known as gum disease. In Japan, 80% of adults aged 35 and over suffer from this disease. What's more, P. gingivalis has also been linked to rheumatoid arthritis, cardiovascular disease, pancreatic cancer, and even Alzheimer's disease.

15 Apr 2020

Fatty acids could be effective platform for drug delivery

Triglycerides have long been treated as a threat to human health. Now, researchers believe they could be an effective drug delivery platform.

1 Apr 2020

Mass Spectrometry‐Based Strategies for Therapeutic Antibodies Extensive Characterization and Optimization

For many years’ antibodies have been used in therapeutic applications to treat a plethora of diseases and ailments.

17 Feb 2020