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New report highlights coffee's effect on sleep

The Institute for Scientific Information on Coffee (ISIC) published a new report today, titled 'Coffee and sleep in everyday lives', authored by Professor Renata Riha, from the Department of Sleep Medicine at the University of Edinburgh.

5 Feb 2021

Unknown root trait allows some cereal plants to grow deeper roots

A previously unknown root trait allows some cereal plants to grow deeper roots capable of punching through dry, hard, compacted soils, according to Penn State researchers, who suggest that harnessing the inherited characteristic could lead to crops better able to deal with a changing climate.

2 Feb 2021

Two cryo-EM studies identify different types of ATP synthase organization

The mitochondrial ATP synthase is energy-converting macromolecular machine that uses the electrochemical potential across the bioenergetic membrane called cristae. This potential is maintained via a membrane curvature that is induced by ATP synthase assembled in dimers.

11 Jan 2021

Researchers reconstruct the chewing motion of an early mammal

Paleontologists at the University of Bonn (Germany) have succeeded in reconstructing the chewing motion of an early mammal that lived almost 150 million years ago.

24 Dec 2020

Advanced methodology reveals structures of Arp2/3 complex within cells

The cells in our body are in motion. Some migrate from A to B to heal wounds or fight pathogens. They do so with the help of small "feet" at the leading edge of migrating cells, so-called lamellipodia.

22 Dec 2020

New technology predicts efficacy of transplanted hEPCs in early stages of ischemic disease

In recent years, the number of high-risk groups for ischemic diseases such as critical limb ischemia where tissues of toe may decay is increasing due to increase in the number of people with obesity, diabetes, and hypertension which are triggered by changes in dietary habits, and consumption of smoking and alcohol.

18 Dec 2020

Researchers use new technique to visualize the world of lipid dynamics

The potential to “see” the inner mechanisms of structures provides the promise of developments in the diagnosis and treatment of various diseases.

19 Nov 2020

New study shows patients' own stem cells can be used to grow new bone

A new, groundbreaking study from the University of Bergen (UiB) shows that a patients' own stem cells can be used to grow new bone. This can potentially help millions of people who are partially edentulous and have insufficient bone for the placement of dental implants.

17 Nov 2020

Researchers use digital endocasts technique to reconstruct surface morphology of canine brains

Based on digital endocranial cast models the canine brain does not increase proportionally with body size. Researchers at ELTE Eötvös Loránd and Kaposvár University in Hungary reconstructed the surface morphology of 28 canine brains, including various dog breeds, wolves, coyotes, and jackals.

23 Oct 2020

New tool can provide non-invasive decision support for treating lung cancer

Personalized treatment options for patients with lung cancer have come a long way in the past two decades. For patients with non-small cell lung cancer, the most common subtype of lung cancer and the leading cause of cancer-related death worldwide, two major treatment strategies have emerged: tyrosine kinase inhibitors and immune checkpoint inhibitors.

19 Oct 2020

Safe, efficient concentration of low volume samples with BioChromato's Smart Evaporator C1

BioChromato Inc. reports how the Department of Bioimaging Information Analysis at Gunma University is benefiting from the ability of its Smart Evaporator C1 to safely and efficiently concentrate low volume samples.

From BioChromato Inc. 9 Oct 2020

Study sheds new light on the structure and function of ‘immortality protein’

The nuclear magnetic resonance spectrometer of Kazan Federal University played a crucial role in analyzing the telomerase of Hansenula polymorpha.

14 Sep 2020

New technology reveals experimental drugs that help suppress the growth and spread of tumor

A new technology that allows researchers to peer inside malignant tumors shows that two experimental drugs can normalize aberrant blood vessels, oxygenation, and other aspects of the tumor microenvironment in non-small cell lung cancer (NSCLC), helping to suppress the tumor's growth and spread, UT Southwestern researchers report.

4 Sep 2020

Exploring evolutionary development of mammalian middle ear based on Cretaceous Jehol fossils

A joint research team led by Dr. MAO Fangyuan from the Institute of Vertebrate Paleontology and Paleoanthropology (IVPP) of the Chinese Academy of Sciences and Prof. MENG Jin from the American Museum of Natural History has reported a new multituberculate mammal, Sinobaatar pani, with well-preserved middle ear bone

28 Aug 2020

Surface structure of SARS-CoV-2 virus offers insights for development of therapeutics

At the start of a COVID-19 infection, the coronavirus SARS-CoV-2 docks onto human cells using the spike-like proteins on its surface. The spike protein is at the centre of vaccine development because it triggers an immune response in humans.

19 Aug 2020

Study reveals coronavirus-specific structure that may lead to new antiviral strategies

By visualizing coronavirus replication in an infected host cell, researchers may have answered a long-standing question about how newly synthesized coronavirus components are able to be incorporated into fully infectious viruses.

7 Aug 2020

4D optical coherence tomography offers insight into embryonic heart development

How a valveless embryonic heart tube pumps blood is a long-standing scientific mystery. Thanks to innovations in light-based technology, fresh insights are now available into the biomechanics of mammalian cardiogenesis-;and in particular, the pumping dynamics of the mammalian tubular embryonic heart.

7 Aug 2020

Specific protein found at high levels in the blood of people with early signs of Alzheimer's

Two decades or more before symptoms arise, plaques of a sticky protein called amyloid begin forming in the brains of people later diagnosed with Alzheimer's disease.

29 Jul 2020

Boosting metabolic resources in the brain could be a way to slow neurodegeneration

Researchers at Vanderbilt University Medical Center have shown for the first time that when one optic nerve in the eye is damaged, as in glaucoma, the opposite optic nerve comes to the rescue by sharing its metabolic energy.

From Vanderbilt University 22 Jul 2020

Advanced cryo-EM reveals stunning details of viral RNA replication complex structure

For the first time, scientists at the Morgridge Institute for Research have generated near atomic resolution images of a major viral protein complex responsible for replicating the RNA genome of a member of the positive-strand RNA viruses, the large class of viruses that includes coronaviruses and many other pathogens.

21 Jul 2020