Enzyme News and Research

RSS

Researchers discover unknown enzyme activity towards human endogenous substrates

Scientists have identified an enzymatic activity towards common drugs as well as significant human endogenous substrates, that was previously not known.

24 Jun 2020

Study sheds light on DNA sculpting properties of enigmatic protein

Sometimes, when something is broken, the first step to fixing it is to break it even more. In a recent example, scientists seeking to understand the mechanism of a DNA-repairing enzyme have discovered that the molecule performs its functions by first marking and then further breaking damaged DNA.

22 Jun 2020

Mouse models help understand the functioning of muscles

The quest to detect all kinds of proteins that constitute the sarcomere, the fundamental contractile unit of muscle cells, led to a surprising revelation.

22 Jun 2020

Fantastic Muscle Proteins And Where To Find Them

Researchers at MDC developed a mouse model that enables them to look inside a working muscle and identify the proteins that allow the sarcomere to contract.

22 Jun 2020

Study reveals mechanism by which propionic acid induces brain disorders

Korea Brain Research Institute (KBRI, headed by Suh Pann-ghill) announced on the 11th that the research team led by Dr. Mun Ji-young revealed the mechanism of autism induced by an imbalance of human gut microorganisms.

19 Jun 2020

New system of gene editing allows for targeted, super-fast DNA repair

In a series of experiments using human cancer cell lines, scientists at Johns Hopkins Medicine say they have successfully used light as a trigger to make precise cuts in genomic material rapidly, using a molecular scalpel known as CRISPR, and observe how specialized cell proteins repair the exact spot where the gene was cut.

18 Jun 2020

Specific gut bacteria can affect cholesterol levels in humans

In the darkest parts of the world where light fails to block out the unfathomable bounty of the stars, look up. There are still fewer specks illuminating the universe than there are bacteria in the world, hidden from sight, a whole universe inside just one human gut.

18 Jun 2020

A new rapid-prototyping system to accelerate the design of biological systems

Northwestern University synthetic biologists have developed a new rapid-prototyping system to accelerate the design of biological systems, reducing the time to produce sustainable biomanufacturing products from months to weeks.

16 Jun 2020

Protein glycosylation plays a major role in DNA methylation

An underlying principle in molecular biology is that “DNA makes RNA makes protein.” The process of gene expression is firmly controlled in various ways.

12 Jun 2020

Overactive enzyme causes an inherited form of hypertension

A Turkish family from a village near the Black Sea first caught the attention of medical researchers in the early 1970s.

12 Jun 2020

'Lab-on-a-chip' technology accurately detects early and advanced breast cancer

A scalable "lab-on-a-chip" technology based on inkjet printing methods detected breast cancer in plasma samples from patients with more than 90% accuracy, according to a new study.

11 Jun 2020

High sodium intake affects health of gut microbiome

Particularly in females with untreated hypertension, reducing salt intake to what's considered a healthier level appears to be good for both their gut microbiome and their blood pressure, scientists report.

10 Jun 2020

Study investigates how cancer adapts its metabolism to overcome treatment

Knowing what cancer will do next could lessen the likelihood of it becoming resistant to treatment. A new Canadian study investigates how cancer adapts its metabolism to potentially overcome therapies still in development.

From University of Toronto 9 Jun 2020

'Fat burning' molecule holds promise for future treatment and prevention of obesity

Obesity affects more than 40 percent of adults in the United States and 13 percent of the global population.

9 Jun 2020

TU Dresden study uncovers enzyme essential for intestinal epithelial differentiation

The intestinal epithelium is the inner layer of the intestinal wall, which separates host tissue from the intestinal microbiota.

9 Jun 2020

Study sheds light on "repurposed" enzymatic reactions

Researchers have identified key ingredients for producing high-value chemical compounds in an environmentally friendly fashion: repurposed enzymes, curiosity, and a little bit of light.

9 Jun 2020

New technology to rapidly create antibody-drug conjugates

A USC School of Pharmacy-led team has engineered a new, faster way to make drugs that precisely target malignant cells - while leaving healthy tissue undamaged - that could lead the way to better treatments for numerous types of cancer.

5 Jun 2020

New image of LSD1 enzyme in action could provide insight into gene regulation

New images of an enzyme in action as it interacts with the chromosome could provide important insight into how cells--including cancer cells--regulate their genes.

5 Jun 2020

Researchers discover how a microRNA protects vascular integrity

Ludwig-Maximilian-Universitaet in Munich researchers have discovered a hitherto unknown molecular function of a specific microRNA that preserves integrity of the endothelium and reduces the risk of atherosclerosis.

5 Jun 2020

Scientists aim to develop a gene-targeting, antiviral agent to combat COVID-19

A team of scientists from Stanford University is working with researchers at the Molecular Foundry, a nanoscience user facility located at the Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab), to develop a gene-targeting, antiviral agent against COVID-19.

5 Jun 2020