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Investigational COVID-19 vaccine is safe, generates neutralizing antibody activity in healthy adults

An investigational vaccine, mRNA-1273, designed to protect against SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), was generally well tolerated and prompted neutralizing antibody activity in healthy adults, according to interim results published online today in The New England Journal of Medicine.

15 Jul 2020

UVA scientists identify oncogene responsible for glioblastoma

Scientists have identified an oncogene (a cancer-causing gene) responsible for glioblastoma, the deadliest brain tumor.

15 Jul 2020

Golgi membrane protein drives growth and invasion of breast cancer

The cover for issue 28 of Oncotarget features Figure 5, "TMEM165 expression levels alters N-linked glycosylation," by Murali, et al., and reported that the TMEM165 protein was not detected in non-malignant matched breast tissues and was detected in invasive ductal breast carcinoma tissues by mass spectrometry.

15 Jul 2020

Fewer but larger doses of radiotherapy are safe for patients with early breast cancer

A lower total dose of radiotherapy delivered in fewer but larger doses is as safe in the long term as breast cancer radiotherapy courses giving multiple small doses, according to the final results of a 10-year study.

15 Jul 2020

Dual inhibitor therapy may be safer for patients with chronic lymphocytic leukemia

Chronic lymphocytic leukemia (CLL) is the most common leukemia in adults. One in four new leukemia cases are CLL.

15 Jul 2020

Study could lead to major improvements in crop production

Research led by scientists at The Australian National University could lead to major improvements in crop production.

15 Jul 2020

High amount of SARS-Cov-2 receptor is present in patients with pre-existing cardiac conditions

Nearly 20% of all COVID-19-associated deaths are from cardiac complications, yet the mechanisms from which these complications arise have remained a topic of debate in the cardiology community.

15 Jul 2020

New link found between impaired brain energy metabolism and delirium

Scientists from Trinity College Dublin have discovered a new link between impaired brain energy metabolism and delirium - a disorienting and distressing disorder particularly common in the elderly and one that is currently occurring in a large proportion of patients hospitalized with COVID-19.

15 Jul 2020

Research helps uncover hidden gene associations in our cells

As cells develop, changes in how our genes interact determines their fate. Differences in these genetic interactions can make our cells robust to infection from viruses or make it possible for our immune cells to kill cancerous ones.

15 Jul 2020

New radiopharmaceutical offers precise diagnosis and treatment of prostate cancer in preclinical studies

Researchers have developed a new pair of agents that show exceptional effectiveness for precision diagnosis and treatment of prostate cancer in preclinical studies.

14 Jul 2020

Researchers identify a novel approach for data storage in DNA

A team of multidisciplinary scientists has identified a novel approach to store in DNA information—“The Wizard of Oz” translated into Esperanto here—with efficiency and accuracy like never before.

14 Jul 2020

Novel approach to analyze organ development through gene analysis in single cells

When cells develop, variations in the interaction of genes of an individual determine their fate. Such variations in genetic interactions can make the individual’s cells powerful against infection from viruses or enable the immune cells to kill the tumor cells.

14 Jul 2020

Researchers engineer new nanobodies from Ilama blood cells against COVID-19 infection

UK scientists declared recently that antibodies extracted from llamas have been demonstrated to neutralize the SARS-CoV-2 virus in laboratory tests.

14 Jul 2020

New study could help develop artificial photosynthetic technology for energy production

Biological membranes perform significant functions in shaping the cell, transporting molecules, sensing the external environment, and producing energy for life.

14 Jul 2020

PET radiotracer is safe and effective for imaging malignant brain tumors

A first-in-human study presented at the Society of Nuclear Medicine and Molecular Imaging 2020 Annual Meeting has demonstrated the safety, favorable pharmacokinetic and dosimetry profile of 64Cu-EBRGD, a new, relatively long-lived PET tracer, in patients with glioblastomas.

14 Jul 2020

Researchers develop bioink to print tissue-mimicking material in 3D printers

A research group led by Daniel Aili, associate professor at Linköping University, has developed a bioink to print tissue-mimicking material in 3D printers.

14 Jul 2020

Early exposure to vaccine-derived antigens can have dramatic effect on antibody diversity

University of Alabama at Birmingham researchers have added fresh evidence that early exposure to vaccine-, bacterial- or microbiota-derived antigens has a dramatic effect on the diversity of antibodies an adult mammal will have to fight future infections by pathogens.

14 Jul 2020

Nano-radiomics uses imaging data to assess changes in the tumor microenvironment

Research has shown that the tumor microenvironment (TME) can help cancers grow and evade the immune response.The TME has even been shown to inhibit cellular immunotherapy, a novel form of treatment in which the cells of a patient's immune system are re-engineered in the lab to attack cancer cells.

14 Jul 2020

PET reveals the existence of inter-organ communication between the heart and kidneys after heart attack

Whole body positron emission tomography (PET) has, for the first time, illustrated the existence of inter-organ communication between the heart and kidneys via the immune system following acute myocardial infarction, or heart attack.

14 Jul 2020

Peter S. Conti awarded 2020 Benedict Cassen Prize for pioneering work in cancer imaging

Peter S. Conti, MD, PhD, known for his pioneering work in the diagnosis and management of cancer, was awarded the Benedict Cassen Prize during the 2020 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging.

14 Jul 2020

Research News and Research

Investigational COVID-19 vaccine is safe, generates neutralizing antibody activity in healthy adults

UVA scientists identify oncogene responsible for glioblastoma

Golgi membrane protein drives growth and invasion of breast cancer

Fewer but larger doses of radiotherapy are safe for patients with early breast cancer

Dual inhibitor therapy may be safer for patients with chronic lymphocytic leukemia

Study could lead to major improvements in crop production

High amount of SARS-Cov-2 receptor is present in patients with pre-existing cardiac conditions

New link found between impaired brain energy metabolism and delirium

Research helps uncover hidden gene associations in our cells

New radiopharmaceutical offers precise diagnosis and treatment of prostate cancer in preclinical studies

Researchers identify a novel approach for data storage in DNA

Novel approach to analyze organ development through gene analysis in single cells

Researchers engineer new nanobodies from Ilama blood cells against COVID-19 infection

New study could help develop artificial photosynthetic technology for energy production

PET radiotracer is safe and effective for imaging malignant brain tumors

Researchers develop bioink to print tissue-mimicking material in 3D printers

Early exposure to vaccine-derived antigens can have dramatic effect on antibody diversity

Nano-radiomics uses imaging data to assess changes in the tumor microenvironment

PET reveals the existence of inter-organ communication between the heart and kidneys after heart attack

Peter S. Conti awarded 2020 Benedict Cassen Prize for pioneering work in cancer imaging

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