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Epigenetic Key Unlocks Treatment Path for Endocrine-Resistant Breast Cancer

Endocrine resistance – a major cause of breast cancer deaths – can be underpinned by an epigenetic change called DNA methylation, researchers at the Garvan Institute of Medical Research have discovered.

10 Jan 2024

Uncovering How Tomatoes Fight Off Notorious Blight

Recently, The Plant Journal’s cover highlighted an innovative study that has garnered attention in the interesting field of plant biology.

10 Jan 2024

Conservation Science Leaps Forward: UF Research Deciphers Bobcat DNA from Tracks

On February 2021, Dave Duffy's children informed him on a Sunday morning that they had just witnessed a bobcat through their home's window, which was located close to the University of Florida's Whitney Laboratory for Marine Bioscience, which is located outside of St. Augustine, Florida.

10 Jan 2024

Bacterial "Freight Elevator" Transports Camouflage Molecule for Immune Evasion

Some bacterial membrane transporters work almost like freight elevators to transport substances through the cell membrane into the interior of the cell. The transporter itself spans the bacterial membrane.

9 Jan 2024

Boosting Post-Transplant Survival: Tailoring Gut Microbiome to Fight GvHD

After stem cell transplantation, the donated immune cells sometimes attack the patients' bodies. This is known as graft versus host disease or GvHD.

9 Jan 2024

Key Cytokine Pairs Driving Sepsis Damage Identified

One of the main causes of death in the ICU is sepsis, which is the result of an infection that causes the immune system to mistakenly target the body.

9 Jan 2024

Researchers Decode Immune System's Role in Epigenetic Clocks

When questioned, "What is your age?" The majority of people gauge by counting their birthdays.

9 Jan 2024

AI Program Reveals Cellular Neighborhoods in Cancer Microenvironments

A novel AI-powered program has been developed by researchers at Children's Hospital of Philadelphia (CHOP) to assist in comprehending how various cells arrange themselves into certain tissues and communicate with one another.

9 Jan 2024

Novel Amino Acid Nanoparticles Offer Hope for Fighting Multi-Drug Resistant Cancers

Amino acids, such as tyrosine and tryptophan, are the fundamental building blocks that make up proteins.

9 Jan 2024

Largest Gestational Diabetes Study Reveals 9 New Genetic Regions

The largest genetic study of gestational diabetes to date has led to a discovery of nine novel genetic regions linked to this severe and common pregnancy complication.

8 Jan 2024

Engineering Plants to Fight Disease with Friendly Bacteria

For the first time, scientists have modified the plant microbiome to increase the amount of “good” bacteria that shield the plant from harm.

8 Jan 2024

Unlocking the Gut's Metabolic Secrets

The variety of enzymes that microbes employ to make energy in the low-oxygen environment of the gut is highlighted by a survey of bacterial genomes.

8 Jan 2024

Breakthrough in Bdellovibrio's Prey Recognition System

Researchers from the Universities of Birmingham and Nottingham have uncovered how naturally occurring antimicrobial predatory bacteria, known as Bdellovibrio bacterivorous, produce fiber-like proteins on their surface to entice prey in a study published on January 4th, 2024, in Nature Microbiology.

8 Jan 2024

New Method Reveals Bacteria's Protein Targeting System

Disease-causing bacteria of the genus Salmonella or Yersinia can use tiny injection apparatuses to inject harmful proteins into host cells, much to the discomfort of the infected person.

5 Jan 2024

B12-Producing Gut Bacteria Modulate Neurotransmitter Levels and Reduce Seizures in C. elegans

A new study published in Nature Cell Biology by Mark Alkema, PhD, professor of neurobiology, establishes an important molecular link between specific B12-producing bacteria in the gut of the roundworm C. elegans and the production of acetylcholine, a neurotransmitter important to memory and cognitive function.

5 Jan 2024

Research Reveals Unforeseen Functions for Autophagy Genes in Neuronal Health and Aging

Autophagy, which declines with age, may hold more mysteries than researchers previously suspected. In the January 4th issue of Nature Aging, it was noted that scientists from the Buck Institute, Sanford Burnham Prebys and Rutgers University have uncovered possible novel functions

5 Jan 2024

Scientists Develop Tiny Human Cerebellums to Decipher Disease and Design Therapies

In a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato, an assistant professor of stem cell biology and regenerative medicine, has pioneered a novel human brain organoid model that generates all the major cell types of the cerebellum, a hindbrain region predominantly made up of two cell types necessary for movement, cognition, and emotion: granule cells and Purkinje neurons.

5 Jan 2024