Immune System News and Research

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New technique reveals the tricks that cancer cells use to avoid immunotherapies

By harnessing the immune system against cancer, immunotherapies have revolutionized the way some types of cancer are treated. But most patients--across cancer types--do not respond, and in most cases, scientists are at a loss as to why.

2 Mar 2021

Protein kinases may offer a solution to treat HIV patients with immunodeficiency

A new study indicates that protein kinases, which initiate the process that erodes the body’s immunity, significantly contribute to the immunodeficiency in HIV patients. Drugs that block these protein kinases may offer a solution to treating HIV patients whose immunity is not restored by antiretroviral therapy.

2 Mar 2021

Study shows how antibodies fight Zika virus

Zika outbreaks are still having lasting effects on children whose mothers were infected with the Zika virus during their pregnancy.

26 Feb 2021

Scientists map previously unknown metabolic pathways to produce memory T cell

Immunologists have plotted a previously unfamiliar biological pathway through which the immune system produces T cells that destroy viruses.

26 Feb 2021

New technology identifies useful genetic designs more efficiently

Joshua Leonard, a synthetic biologist from Northwestern University, used electronic kits to create devices when he was a child.

23 Feb 2021

Genes could help determine the intensity of neutralizing antibodies to COVID-19 virus

While neutralizing antibodies form in less than two weeks of a COVID-19 infection, their intensity and durability can differ from one individual to another.

22 Feb 2021

New hydrogel shrinks tumors in melanoma mice model

Recently, messenger RNA, also called mRNA, vaccines, to combat the COVID-19 infection have made headlines worldwide, but researchers have already been experimenting with mRNA vaccines to prevent or cure other illnesses, including certain types of cancer.

18 Feb 2021

Study identifies how CTLA-4 blockade can disable suppressive immune cells to aid tumor destruction

A Ludwig Cancer Research study has identified a novel mechanism by which a type of cancer immunotherapy known as CTLA-4 blockade can disable suppressive immune cells to aid the destruction of certain tumors.

18 Feb 2021

Study reveals a major genetic risk factor for severe COVID-19

In 2020, a research team demonstrated that a significant genetic risk factor for severe COVID-19 infection was inherited from Neanderthals.

17 Feb 2021

Tumor microenvironment could improve cancer immunotherapy

A study has revealed how chemicals surrounding tumors, the tumor microenvironment, undermine the immune system and allow cancer to resist attack.

From University of Pittsburgh 16 Feb 2021

New understanding of tumor microenvironment could help enhance immunotherapy

A paper published today in Nature shows how chemicals in the areas surrounding tumors--known as the tumor microenvironment--subvert the immune system and enable cancer to evade attack. These findings suggest that an existing drug could boost cancer immunotherapy.

From University of Pittsburgh 16 Feb 2021

Machine learning approach to identify drugs that could be repurposed to fight Covid-19

When the Covid-19 pandemic struck in early 2020, doctors and researchers rushed to find effective treatments.

16 Feb 2021

Animal model yields important insights into T cell exhaustion

T lymphocytes, or T cells, are an important component of our immune system. They can recognize foreign proteins, so-called antigens, as peptide fragments - for instance, those derived from viruses or cancer cells.

15 Feb 2021

Study reveals a new role of SRC-3 protein in various cancers

New research has revealed a new role of the steroid receptor coactivator 3, also called SRC-3/NCOA3.

15 Feb 2021

New AI-based method produces new diversity of AAV capsids for optimized gene therapy

Dyno Therapeutics has demonstrated the use of AI to created an unparalleled range of adeno-associated virus capsids that can evade the immune system.

15 Feb 2021

Seasonal human coronavirus antibodies not associated with protection against SARS-CoV-2

Past exposure to seasonal coronaviruses (CoVs), which cause the common cold, does not result in the production of antibodies that protect against the novel coronavirus SARS-CoV-2, according to a study led by Scott Hensley, PhD, an associate professor of Microbiology at the Perelman School of Medicine at the University of Pennsylvania.

11 Feb 2021

Inherited genetic variation plays a role in how patients respond to cancer immunotherapy

For all their importance as a breakthrough treatment, the cancer immunotherapies known as checkpoint inhibitors still only benefit a small minority of patients, perhaps 15 percent across different types of cancer. Moreover, doctors cannot accurately predict which of their patients will respond.

11 Feb 2021

New therapeutic approach to restore the effectiveness of immune cells

Prompted by the need to improve conventional treatments for people infected with the human immunodeficiency virus (HIV-1), a team from the Institut national de la recherche scientifique (INRS) has identified a therapeutic approach to restore the effectiveness of immune cells.

10 Feb 2021

Mast Cells: High-speed messengers of the immune defense

In order to fight pathogens, mast cells regulate inflammatory reactions of the immune system.

10 Feb 2021

Certain coronaviruses steal hosts’ genes to evade their immune system

Certain coronaviruses can add some genes, that belong to the host they infected, to their genetic pool. In this manner, they can merge and be less noticeable in the immune system.

9 Feb 2021

Immune System News and Research

New technique reveals the tricks that cancer cells use to avoid immunotherapies

Protein kinases may offer a solution to treat HIV patients with immunodeficiency

Study shows how antibodies fight Zika virus

Scientists map previously unknown metabolic pathways to produce memory T cell

New technology identifies useful genetic designs more efficiently

Genes could help determine the intensity of neutralizing antibodies to COVID-19 virus

New hydrogel shrinks tumors in melanoma mice model

Study identifies how CTLA-4 blockade can disable suppressive immune cells to aid tumor destruction

Study reveals a major genetic risk factor for severe COVID-19

Tumor microenvironment could improve cancer immunotherapy

New understanding of tumor microenvironment could help enhance immunotherapy

Machine learning approach to identify drugs that could be repurposed to fight Covid-19

Animal model yields important insights into T cell exhaustion

Study reveals a new role of SRC-3 protein in various cancers

New AI-based method produces new diversity of AAV capsids for optimized gene therapy

Seasonal human coronavirus antibodies not associated with protection against SARS-CoV-2

Inherited genetic variation plays a role in how patients respond to cancer immunotherapy

New therapeutic approach to restore the effectiveness of immune cells

Mast Cells: High-speed messengers of the immune defense

Certain coronaviruses steal hosts’ genes to evade their immune system

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