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Genetic makeup of neuroblastoma shows marked spatial and temporal variability

Tumors are heterogeneous, which means that different parts of the same tumor can be genetically distinct. This phenomenon, known as intratumor heterogeneity, is steadily gaining in significance within the field of cancer research.

13 Dec 2021

Research offers alternative cell option for organs-on-chips

Organ-on-a-chip technology has provided a push to discover new drugs for a variety of rare and ignored diseases for which current models either don't exist or lack precision. In particular, these platforms can include the cells of a patient, thus resulting in patient-specific discovery.

13 Dec 2021

Detachable head-mounted photoacoustic microscope images brain activity in mice

Scientists recently generated the first detachable head-mounted photoacoustic microscope for imaging brain activity in freely roaming mice.

13 Dec 2021

Multiple exposure enhances antibody efficacy against COVID-19 variants

Antibodies produced by the immune system against the SARS-CoV-2 spike protein help pinpoint and avoid future infections.

13 Dec 2021

Study of people from diverse ancestries provides a powerful tool for predicting heart disease risk

In a large-scale study of people from diverse ancestries, researchers narrowed down the number of genomic variants that are strongly associated with blood lipid levels and generated a polygenic risk score to predict elevated low-density lipoprotein cholesterol levels, a major risk factor for heart disease.

From National Human Genome Research Institute (NHGRI) 9 Dec 2021

Immune cells utilize the body’s fat stores to combat infection, says study

A recent study carried out by the University of East Anglia and Quadram Institute shows how immune cells utilize the body’s fat stores to combat infection.

9 Dec 2021

World's first metal-organic framework antibody-drug delivery system developed

It sounds like the stuff of science fiction: a man-made crystal that can be attached to antibodies and then supercharge them with potent drugs or imaging agents that can seek out diseased cells with the highest precision, resulting in fewer adverse effects for the patient.

8 Dec 2021

Study reveals mechanism by which infections strengthen the immune system

Over time, the immune system in humans weakens making older adults more prone to infections. This leaves researchers with the puzzling dilemma of retaining health throughout the lifespan.

7 Dec 2021

Massive study on plasma proteome enhances understanding of human diseases

Recent research by investigators from deCODE genetics revealed how proteins drastically enhance the understanding of human diseases.

7 Dec 2021

People previously infected by Chikungunya virus may develop partial immunity to Mayaro virus

A study conducted at the University of São Paulo (USP) in Brazil suggests people previously infected by Chikungunya virus may develop partial immunity to Mayaro virus.

6 Dec 2021

Duke engineers develop a rapid test to identify antibody effectiveness against COVID-19 variants

Biomedical engineers at Duke University have devised a test to quickly and easily assess how well a person's neutralizing antibodies fight infection from multiple variants of COVID-19 such as Delta and the newly discovered Omicron variant.

6 Dec 2021

Long-term exposure to particulate matter associated with hypertension

According to the WHO, air pollution is the greatest health risk worldwide, accounting for more than 4.2 million deaths annually.

6 Dec 2021

Announcing the Winners of The Scientist’s Top 10 Innovations of 2021

Each year The Scientist seeks to highlight the latest and greatest tools, technologies, and techniques to hit the life science landscape.

From Resolve Biosciences 6 Dec 2021

Daytime eating maintains circadian alignment, prevents glucose intolerance despite mistimed sleep

What are the effects of eating during the nighttime instead of the daytime? New research, focused on a simulation of night shift work, may hold implications for people eating at atypical times -; like those experiencing jet lag, circadian rhythm sleep disorders, or who tend to sleep late during the weekends.

6 Dec 2021

Immune cells in the brain mediate the link between gut microbiome and amyloid beta deposits

New research from the University of Chicago points to microglia, key immune cells in the brain, as a key mediator in the relationship between the gut microbiome and b-amyloid deposits in male mice in a model of Alzheimer's disease.

3 Dec 2021

Integration of digital and molecular data could enable individualized prevention of disease

Analyzing molecular characteristics and their variation during lifestyle changes, by combining digital tools, classical laboratory tests and new biomolecular measurements, could enable individualised prevention of disease.

3 Dec 2021

Natural anti-inflammatory compound in rosemary plants may benefit postpartum dairy cows

Rosemary and dairy cows could be a winning combination.

3 Dec 2021

Researchers identify a new approach to triggering differentiation in acute myeloid leukemia

In the late 1980s, scientists developed a revolutionary approach to treating acute myeloid leukemia (AML), a type of blood cancer. Called differentiation therapy, it amounted to a bona fide cure for many patients.

2 Dec 2021

Next-generation sequencing for minimal residual disease proven more sensitive than flow cytometry

In pediatric and young adult patients with acute lymphoblastic leukemia (ALL) treated with tisagenlecleucel (Kymriah), DNA sequencing-based detection of residual disease between three and 12 months accurately identified all patients who would eventually relapse, while other methods were less predictive.

2 Dec 2021

Nanoparticles mimicking flu viruses to deliver large biological drug molecules

Nanoengineers from the University of California San Diego recently created a new and potentially efficient means to deliver messenger RNA (mRNA) into cells.

2 Dec 2021

Blood News and Research

Genetic makeup of neuroblastoma shows marked spatial and temporal variability

Research offers alternative cell option for organs-on-chips

Detachable head-mounted photoacoustic microscope images brain activity in mice

Multiple exposure enhances antibody efficacy against COVID-19 variants

Study of people from diverse ancestries provides a powerful tool for predicting heart disease risk

Immune cells utilize the body’s fat stores to combat infection, says study

World's first metal-organic framework antibody-drug delivery system developed

Study reveals mechanism by which infections strengthen the immune system

Massive study on plasma proteome enhances understanding of human diseases

People previously infected by Chikungunya virus may develop partial immunity to Mayaro virus

Duke engineers develop a rapid test to identify antibody effectiveness against COVID-19 variants

Long-term exposure to particulate matter associated with hypertension

Announcing the Winners of The Scientist’s Top 10 Innovations of 2021

Daytime eating maintains circadian alignment, prevents glucose intolerance despite mistimed sleep

Immune cells in the brain mediate the link between gut microbiome and amyloid beta deposits

Integration of digital and molecular data could enable individualized prevention of disease

Natural anti-inflammatory compound in rosemary plants may benefit postpartum dairy cows

Researchers identify a new approach to triggering differentiation in acute myeloid leukemia

Next-generation sequencing for minimal residual disease proven more sensitive than flow cytometry

Nanoparticles mimicking flu viruses to deliver large biological drug molecules

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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