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A Study on Genetic Markers and Their Efficiency in the Cultivation of High-Quality Rice

For individual organisms, genetic markers, like simple sequence repeat (SSR), fragment length polymorphisms (RFLP), and single-nucleotide polymorphisms (SNPs), offer unique identifiers. This helps in the determination of important genetic variations in plants, enabling modern plant breeding to choose high-quality crop varieties.

26 Apr 2023

Next-Generation Sequencing Provides New Insights into Mutations of Mitochondrial DNA

A high-throughput single-cell single-mitochondrial genome sequencing technology known as iMiGseq has provided new insights into mutations of mitochondrial DNA (mtDNA) and offers a platform for assessing mtDNA editing strategies and genetic diagnosis of embryos prior to their implantation.

17 Apr 2023

Optimized Genome-Editing Method Vastly Reduces Mutations

CRISPR-Cas9 is frequently used to alter the genome by researching and editing disease-related genes. However, this approach is coupled with undesirable side effects including mutations and toxicity.

11 Apr 2023

Novel Method can Measure the Abundance and Modification of tRNA Molecules in a Single Step

Ribonucleic acid (RNA) molecules are present in all living cells, with different types of RNA having different jobs.

7 Apr 2023

Tiny Protein Interacts with Ion Channels to Make Our Eyes Sensitive to Dim Light

Using cryo-electron microscopy and mass spectrometry, researchers from PSI have deciphered the structure of an ion channel found in the eye while it interacts with the protein calmodulin – a structure that has eluded scientists for three decades.

4 Apr 2023

First Steps Driving Antibiotic Resistance Discovered

Antibiotic resistance is a global health threat. In 2019 alone, an estimated 1.3 million deaths were attributed to antibiotic resistant bacterial infections worldwide.

3 Apr 2023

Uncovering the evolutionary history of wheat during the Holocene

Over 35% of the world’s population is nourished by wheat, which includes bread wheat and its relatives. Wheat has been cultivated for more than 10,000 years, beginning with the “Neolithic Revolution,” and is one of the earliest ancient crops to emerge in the Fertile Crescent.

21 Mar 2023

New insights into the distribution and regulation of meiotic DSB hotspots

A new method, DNA End tailing and sequencing (DEtail-seq), for meiotic DNA double-strand break (DSB) profiling was developed recently.

3 Mar 2023

New signals of natural selection in humans identified

A team of global experts has discovered new signals of natural selection in humans.

2 Mar 2023

New compound found in cigarette smoke damages human lung cells’ DNA

Once in a while, people are exposed to possibly detrimental substances in the environment or through their habits or diets. For instance, a compound discovered in cigarette and industrial smoke, benzo(a)pyrene (BaP), is responsible to damage DNA.

23 Feb 2023

Study identifies genetic variants linked to mathematical abilities in children

A new study published in Genes, Brain and Behavior has identified several genetic variants that may be linked with mathematical abilities in children.

23 Feb 2023

Metabolic reactions upon activating Akt2 enzyme revealed

Takeaki Ozawa and his team from the University of Tokyo reveal the metabolic reactions upon activating an enzyme called Akt2.

22 Feb 2023

New approach to rapidly determine biological aging

Telomeres-;the caps at the ends of chromosomes that protect our genetic materials from the brunt of cellular wear and tear-;are known to shorten and fray over time.

16 Feb 2023

Gaining insights into human disease biology through CRISPR platforms

In this interview, we speak with Laralynne Przybyla about how she is utilizing CRISPR platforms to understand human disease biology in greater detail.

From Society for Laboratory Automation and Screening (SLAS) 7 Feb 2023

Researchers establish and characterize a stable iPSC line for modeling human disease

Bill Skarnes and team established and characterized a stable iPSC line, KOLF2.1J, to act as a high-quality baseline platform for modeling human disease.

3 Feb 2023

Blending multiple maps uncover new genetic causes of blindness

In a new study, Ran Elkon and Ruth Ashery-Padan of Tel Aviv University, Israel, and colleagues discovered a new genetic risk factor for adult-onset macular degeneration (AMD) by combining a map of gene regulatory sites with disease-associated loci.

18 Jan 2023

New effort to generate high quality reference genomes for 1,000 known species of euglenoids

The Euglena International Network (EIN) (https://euglenanetwork.org/), founded in 2020, is a global consortium of hundreds of scientists around the world with the collective goal of supporting euglenoid science through collaborative and integrative omics between academics and industry.

23 Nov 2022

Applying “programmable molecular scissors” to combat COVID-19 infection

As an approach that could be used to create a new class of antiviral drugs, synthetic biology was used by Cambridge scientists to artificially create enzymes programmed to attack the genetic code of SARS-CoV-2 and eliminate the virus.

17 Nov 2022

A new outlook on sow breeding using dietary nucleotides

The primary fetal organ systems’ growth and development are strongly influenced by the nutrition status of the mother. Late gestation is when fetal growth is rapidly accelerated, and the nutritional needs of sows rise dramatically as a result of the fetus’ rapid growth and the placenta’s quick expansion.

26 Oct 2022

An accurate overview of gene activity could provide targeted therapies

Normal gene activity in the afflicted cells is changed during pathological events. Therefore, obtaining a precise picture of gene activity could hold the key to the creation of new, targeted therapies.

18 Oct 2022