RNA Sequencing News and Research

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Towards A Better Understanding of Early Human Embryonic Development

Despite being an essential developmental process, the understanding of human embryonic genome activation is limited, owing to the lack of in vitro cell models and ethical concerns.

22 Sep 2023

The Intriguing Phenomenon of Cellular Reprogramming

A fascinating phenomenon of cellular reprogramming in developed adult organs has been revealed by researchers, providing insight into a brand-new process of adaptive development.

12 Sep 2023

Scale Biosciences Continues Commercial Expansion with Introduction of New and Differentiated Single Cell Methylation and Single Cell RNA Sequencing Solutions

Scale Biosciences, Inc. (ScaleBioTM), an innovator in single cell sequencing leveraging combinatorial indexing technologies, today announced an expansion of their product portfolio to enable a broader range of single cell omics experiments and unlock new translational research applications.

30 Aug 2023

New Findings May Provide Useful Therapeutic Approach for Treating Breast Cancer Patients

A new editorial paper was published in Oncotarget's Volume 14 on June 12, 2023, entitled, "Are cis-spliced fusion proteins pathological in more aggressive luminal breast cancer?"

21 Aug 2023

Stem Cells Used to Create Tooth Enamel in the Lab

Organoids have now been created from stem cells to secrete the proteins that form dental enamel, the substance that protects teeth from damage and decay.

16 Aug 2023

Targeting Long-read RNA Sequencing with Low-Cost Technology

Researchers at the Children’s Hospital of Philadelphia (CHOP) have created a flexible and affordable approach for targeted sequencing of full-length RNA molecules, which might hasten the development of novel diagnostics and therapies.

16 Aug 2023

Researchers Identify Key Cells Involved in the Process of Cartilage Regeneration in Lizards

A team of researchers from the Keck School of Medicine of USC have published the first detailed description of the interplay between two cell types that allow lizards to regenerate their tails.

11 Aug 2023

New Nanopore Technology Can Identify Single-Molecule Protein Variations

A group of researchers guided by the University of Oxford has made significant progress in detecting changes in protein structures. The method, which was published in Nature Nanotechnology, uses novel nanopore technology to detect structural variations at the single-molecule level, even deep within long protein chains.

2 Aug 2023

Single-Cell Sequencing Finds New Cell Types in the Visual Systems of Flies

Researchers from New York University have created a method that discovers and labels neurons throughout development, which has allowed them to identify novel cell types in the visual system of flies.

1 Aug 2023

The First Data Set Decoding RNA-Driven Phase Separations

High levels of semi-extractable RNAs are present in membraneless organelles in cells, and these RNAs could one day serve as biomarkers or therapeutic targets.

19 Jul 2023

Study Reveals Key Insights Into the Evolution of Tumor Microenvironment in Gastric Cancer

A new study led by researchers at The University of Texas MD Anderson Cancer Center provides a deeper understanding of the evolution of the tumor microenvironment during gastric cancer progression.

7 Jul 2023

Tiny Sea Creature Offers Insights into Healing and Aging

National Institutes of Health researchers and their collaborators revealed fresh insights into healing and aging by studying how a small marine creature regenerates a completely new body from only its mouth.

3 Jul 2023

New Data Shows Gene Expression at Different Stages of Pregnancy

While the exterior features of a woman can alter throughout pregnancy, scientists are surprisingly ignorant about the interior biological changes that take place.

14 Jun 2023

New Stem Cell Technique to Revolutionize Stem Cell Research

Studies of the interaction between human genetics and biology on a wide scale have been made possible by a potent new stem cell technology.

12 Jun 2023

Scientists Discover a New Step in the Differentiation of Precursor Cells Into Mature Basophils

Big changes often happen in small steps, and it's not always easy to see how we get from point A to point B.

8 Jun 2023

Molecular Rhythms of Malaria Parasites Sync With the Biological Clock of Human Hosts

Health officials warn that drug resistance could wipe out recent progress against malaria, particularly in Africa and southeast Asia.

7 Jun 2023

Charting a High-Resolution Roadmap for Regeneration of Pancreatic β Cells

At the Shanghai Institute of Nutrition and Health (SINH) of the Chinese Academy of Sciences (CAS), a research group headed by Professor Zhen Shao and the collaborators plotted a high-resolution roadmap for the process of pancreatic β cell regeneration by in vivo transdifferentiation from adult acinar cells with the help of a single-cell RNA sequencing (scRNA-seq) technology.

31 May 2023

New Insights Into How Genetic Variants Impact Gene Expression

The Department of Biomedical Informatics (DBMI) at the University of Colorado School of Medicine, in collaboration with the University of California San Francisco and Stanford University, has recently published a study that is the largest of its kind to focus on ancestry correlations with biomedical traits.

26 May 2023

Ex Vivo Expansion of HSCs Using a Novel Culture System

Hematopoietic stem cells (HSCs) are immature blood cells found in the bone marrow that can be stimulated to develop into any type of blood cell.

25 May 2023

A High-Throughput Assay for Identifying and Validating ECHS1 Enzyme Genetic Variants

The enzyme variations of mitochondrial enoyl-CoA hydratase short-chain 1 (ECHS1) are dysfunctional. In Japan, they are mostly responsible for mitochondrial disease.

19 May 2023