Structural Biology News and Research

RSS

Yale and uOttawa researchers partner to solve a puzzle rooted in the deepest past of evolution

For decades, scientists have been trying to unravel an enduring mystery of structural biology: Why do two otherwise identical protein forms found in everything from plants, amphibians and human beings hang onto a slight variation across the mighty span of evolution?

21 Mar 2022

Researchers use GP2 and UMOD to prevent urinary tract infection

A team led by Karolinska Institute used AI and structural biology to learn more about two similar proteins that protect against bacterial infection in the urinary tract.

16 Mar 2022

Research points to a common thread linking diverse neurodegenerative diseases

Take a cell-deep tour of a brain afflicted with Alzheimer's disease, and you will find minuscule clumps of protein that seem suspicious. Ever since the 1980s, when neuroscientists began identifying these protein tangles, researchers have discovered that other brain diseases have their own tangled-protein signatures.

7 Mar 2022

Researchers redevelop Cas9 that is unlikely to cut the wrong DNA

At times, the molecular machinery makes alterations to the wrong part of a host’s genome, generating the likelihood of an effort to repair a genetic mutation.

4 Mar 2022

Cryo-electron microscopy reveals structures of a muscle-type nicotinic acetylcholine receptor

New research co-led by a University of Ottawa Faculty of Medicine professor is shedding light on some of the mysterious dynamics that define the interplay between nerves and muscle.

17 Feb 2022

Programming DNA Robots to Prod Cell Membranes

In this interview, we speak to Dr. Matthew Baker about his latest research that led to the programming of DNA 'robots' that are able to prod cell membranes.

From The University of New South Wales (UNSW) 14 Feb 2022

Study suggests Cx43 hemichannels as potential new target for osteoporosis treatments

Channels on the surface of bone cells called osteocytes help build stronger bones in response to mechanical stress, shows a study published today in eLife.

9 Feb 2022

Researchers discover a sustainable approach for drug development

Although several people think of medicines as purely synthetic compounds, nature is an important element of most of the medications humans depend on.

4 Feb 2022

Cryo-ET reveals mechanisms underlying gene mutations that lead to blindness

Researchers have discovered the structural determinants of the highly specialized rod outer segments membrane architecture of the eye, which plays a crucial role in vision.

7 Jan 2022

Unraveling how DNAzymes work in real time

DNAzymes are precision biocatalysts that destroy unwanted RNA molecules. However, major obstacles to their use in medicine remain.

23 Dec 2021

Scientists unravel the structure of octopus-like Lassa viral polymerase

Endemic in Western African countries, Lassa virus is transmitted to humans through food or household items that are contaminated with the urine or faeces of Mastomys rats.

7 Dec 2021

Creating a Biological Clock in a Test Tube

We speak to researchers from the UC San Diego Center for Circadian Biology about their latest research that led to the development of a biological clock in a test tube.

From UC San Diego 6 Dec 2021

UD biochemist explores how mRNA eraser enzymes work in our cells

University of Delaware biochemist Jeff Mugridge is trying to figure out how so-called mRNA eraser enzymes work in our cells, why those erasers can sometimes misbehave and lead to cancer, and how science can pave the way for possible solutions to this problem.

25 Nov 2021

Research demonstrates how diet affects immunity through the gut microbiome

The cliché "you are what you eat" has been used for hundreds of years to illustrate the link between diet and health. Now, an international team of researchers has found the molecular proof of this concept, demonstrating how diet ultimately affects immunity through the gut microbiome.

From Harvard Medical School 17 Nov 2021

Structural Biology News and Research

Yale and uOttawa researchers partner to solve a puzzle rooted in the deepest past of evolution

Researchers use GP2 and UMOD to prevent urinary tract infection

Research points to a common thread linking diverse neurodegenerative diseases

Researchers redevelop Cas9 that is unlikely to cut the wrong DNA

Cryo-electron microscopy reveals structures of a muscle-type nicotinic acetylcholine receptor

Programming DNA Robots to Prod Cell Membranes

Study suggests Cx43 hemichannels as potential new target for osteoporosis treatments

Researchers discover a sustainable approach for drug development

Cryo-ET reveals mechanisms underlying gene mutations that lead to blindness

Unraveling how DNAzymes work in real time

Scientists unravel the structure of octopus-like Lassa viral polymerase

Creating a Biological Clock in a Test Tube

UD biochemist explores how mRNA eraser enzymes work in our cells

Research demonstrates how diet affects immunity through the gut microbiome

Scientists use AI and evolutionary analysis to produce 3D models of eukaryotic protein interactions

Horse hyperimmune antibody may be an efficient approach to combat SARS-CoV-2

Scientists use DNA to create what may be the world's tiniest ruler for measuring proteins

Researchers refine cryogenic electron microscopy technique

Researchers reconstitute the biological clock to better understand circadian rhythms

Study pinpoints means to restore the efficacy of drugs for acute myeloid leukemia

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Latest in Genomics