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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Study could help develop peptide siRNA carrier for human oral cancer

MUSC Hollings Cancer Center researchers are exploring the use of peptide carriers for the delivery of small RNA drugs as a novel treatment for cancer. The team's recent work, published online March 19 in the Molecular Therapy - Nucleic Acids journal, lays the foundation for developing a clinically relevant peptide carrier RNAi-based drug treatment strategy for human oral cancer.

25 May 2021

“Paralyzed” immune cells can be reactivated by drugs in IDH-mutant gliomas

Brain tumor cells with a certain common mutation reprogram invading immune cells. This leads to the paralysis of the body's immune defense against the tumor in the brain. Researchers from Heidelberg, Mannheim, and Freiburg discovered this mechanism and at the same time identified a way of reactivating the paralyzed immune system to fight the tumor.

25 May 2021

New method helps tests large groups for SARS-CoV-2 infection

Researchers at the Vienna BioCenter designed a testing protocol for SARS-CoV-2 that can process tens of thousands of samples in less than 48 hours. The method, called SARSeq, is published in the journal Nature Communications and could be adapted to many more pathogens.

25 May 2021

Researchers study the origins of life using modern ecological biosignature

While searching for signs of life, scientists often look for chemicals, biosignatures, or phenomena that suggest the presence of current or past life. However, it is not always the case that signs of life on Earth are also signs of life in other planetary ecosystems.

21 May 2021

Successful class of therapeutics attack and shut down unique and harmful genes

A potential class of therapeutics that uses synthetic nucleic acids to attack and shut down harmful genes while preventing viral spread is gathering momentum.

18 May 2021

New kind of biomolecule could play a vital role in the biology of all living things

Stanford researchers have discovered a new kind of biomolecule that could play a significant role in the biology of all living things.

18 May 2021

Study shows that inactivation of BRG1 leads to high genetic instability

Following the p53 tumor suppressor gene, the genes encoding two proteins of the SWI/SNF chromatin remodeling complex are the most often identified mutated.

17 May 2021

Mutations in GEMIN5 protein can cause rare genetic disorders in children

Researchers have discovered a genetic cause of an unusual neurological disorder characterized by developmental delay, known as ataxia.

From University of Pittsburgh 10 May 2021

Supercoiling characteristic of DNA's structure controls gene expression, research shows

The two meters of -stretched- DNA contained in human cells are continuously twisting and untwisting to give access to genetic information: when a gene is expressed to generate a protein, the two strands of DNA are separated to give access to all the machinery necessary for this expression, resulting in an excessive accumulation of coiling that needs to be resolved later.

10 May 2021

Research uncovers how antibiotics target bacterial RNA Polymerase to inhibit gene transcription

The emergence and spread of new forms of resistance remains a concern that urgently demand new antibiotics. Transcription is a vital process in bacterial cell, where genetic information in DNA is transcribed to RNA for the translation of proteins that perform cellular function.

6 May 2021

“Chemical nose” smells vital variations in unusual folding of DNA structures

Small variations in the structure of DNA have been related to breast cancer and other diseases, but they have been incredibly hard to find so far.

6 May 2021

Changes in protein provide a better understanding of age-related changes in the kidney

New research suggests that studying protein modifications in the kidneys as people age will help provide a complete picture of the age-related processes that occur in these organs.

6 May 2021

New atlas may support present and future conservation efforts to protect coral reefs

A team of researchers has created the world’s first atlas of all the different types of cells in a reef-building stony coral that inhabits the Indo-Pacific oceans.

5 May 2021

Study reveals relationship between form and function in the genetic material of dinoflagellates

A new study unfolds a longstanding puzzle about the connection between the function and form in the genetic material of a complex group of algae.

5 May 2021

Study finds how SARS-CoV-2 hijacks human cell machinery to disrupt the immune response

SARS-CoV-2 hijacks human cell machinery to disrupt the immune response, enabling it to cause infection, replicate, and cause disease.

4 May 2021

New nanopore sequencing tool can identify the existence of nucleobases

Nanopore technology has the potential to enable the development of portable, low-cost, small devices capable of real-time DNA sequencing.

4 May 2021

Researchers identify specific proteins that play a key role in the development of dendritic cells

The human immune system comprises functionally specialized cellular defense mechanisms that protect the body against disease.

3 May 2021

Study shows that autophagy plays a key role in messenger RNA degradation

Autophagy is essential in messenger RNA (mRNA) degradation, according to researchers from the Tokyo Institute of Technology (Tokyo Tech).

27 Apr 2021

National DNA Day 2021: An Interview with Professor George Church

In celebration of National DNA Day, AZoLifeSciences interviews renowned DNA expert Professor George Church about his life-long career in DNA research.

From Harvard Medical School 23 Apr 2021

Study identifies mechanism that enables SARS viruses to efficiently replicate in infected cells

Researchers have now identified how SARS viruses improve the production of viral proteins in infected cells such that new copies of the virus can be produced.

23 Apr 2021

RNA News and Research

Study could help develop peptide siRNA carrier for human oral cancer

“Paralyzed” immune cells can be reactivated by drugs in IDH-mutant gliomas

New method helps tests large groups for SARS-CoV-2 infection

Researchers study the origins of life using modern ecological biosignature

Successful class of therapeutics attack and shut down unique and harmful genes

New kind of biomolecule could play a vital role in the biology of all living things

Study shows that inactivation of BRG1 leads to high genetic instability

Mutations in GEMIN5 protein can cause rare genetic disorders in children

Supercoiling characteristic of DNA's structure controls gene expression, research shows

Research uncovers how antibiotics target bacterial RNA Polymerase to inhibit gene transcription

“Chemical nose” smells vital variations in unusual folding of DNA structures

Changes in protein provide a better understanding of age-related changes in the kidney

New atlas may support present and future conservation efforts to protect coral reefs

Study reveals relationship between form and function in the genetic material of dinoflagellates

Study finds how SARS-CoV-2 hijacks human cell machinery to disrupt the immune response

New nanopore sequencing tool can identify the existence of nucleobases

Researchers identify specific proteins that play a key role in the development of dendritic cells

Study shows that autophagy plays a key role in messenger RNA degradation

National DNA Day 2021: An Interview with Professor George Church

Study identifies mechanism that enables SARS viruses to efficiently replicate in infected cells

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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