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Scientists Design Proteins to Reach Hidden Cellular Targets

Drug developers have long faced challenges in reaching targets embedded within the cell membrane because of the membrane's complex biochemical properties. Chemists at Scripps Research have now shown that novel, specially made proteins are capable of effectively reaching these “intramembrane” targets.

14 Mar 2024

Method Seeks to Eliminate the Need for Frozen mRNA Vaccines

CEPI has provided funding to a public research university in Belgium to investigate whether a novel vaccine stabilization method could eliminate the need for mRNA vaccines to be stored in frozen storage and enable a quick and expanded response to future outbreaks in as little as 100 days.

14 Mar 2024

Breakthrough: Transgenic Cow Produces Human Insulin in Milk

An unassuming brown bovine from the south of Brazil has made history as the first transgenic cow capable of producing human insulin in her milk.

14 Mar 2024

Research Reveals the Impact of Activated Protein C on Alzheimer's Disease Pathology

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 4, entitled, "Single-Cell RNA-seq reveals transcriptomic modulation of Alzheimer's disease by activated protein C."

14 Mar 2024

Researchers Unveil Simple Trick to Improve Accuracy Of Plant Genetics Research

Researchers have published a simple trick that improves the accuracy of techniques that help us understand how external variables – such as temperature – affect gene activity in plants.

14 Mar 2024

Dual-Target CAR T Cell Therapy Shows Promise Against Recurrent Glioblastoma

Targeting two brain tumor-associated proteins-;rather than one-;with CAR T cell therapy shows promise as a strategy for reducing solid tumor growth in patients with recurrent glioblastoma (GBM), an aggressive form of brain cancer, according to early results from the first six patients treated in an ongoing Phase I clinical trial led by researchers from the Perelman School of Medicine at the University of Pennsylvania and Penn Medicine's Abramson Cancer Center.

14 Mar 2024

Widespread Gene Flow Marks Unique Evolutionary History in Giraffes

Evolutionary biologists and non-experts alike have always held a special place in their minds for giraffes, with their bizarre body plans.

13 Mar 2024

Study Reveals Key Role of STAP-1 in Immune Function

A recent study has illuminated the significance of the protein STAP-1 in activating specific immune cells.

13 Mar 2024

Investigating the Antibacterial Effects of T1-Spanin on Antibiotic-Resistant Bacteria

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13 Mar 2024

The Evolution of Plant Cell Analysis with RevGel-seq Technique

Plant cell analysis has been completely transformed by recent advances in single-cell RNA sequencing (scRNA), such as the recently created “RevGel-seq” technique.

13 Mar 2024

Study Reveals Unique Bacterial Fingerprints and Their Impact on Health

The trillions of bacteria that call your body home -; collectively known as the microbiome -; appear to be unique to you, like a fingerprint.

13 Mar 2024

New CRISPR Method Allows Comprehensive Screening of Cancer Mutations

Tumors can carry mutations in hundreds of different genes, and each of those genes may be mutated in different ways -; some mutations simply replace one DNA nucleotide with another, while others insert or delete larger sections of DNA.

13 Mar 2024

Study Identifies Protein Key to Preserving Neuronal Identity

Epigenetic processes allow different cell types to emerge from a single genome. Throughout development, cells differentiate and acquire distinct characteristics by expressing the same genome in different ways.

13 Mar 2024

NIH Researchers Map Vulnerable Sites on Epstein-Barr Virus gp42 Protein

Studies of interactions between two lab-generated monoclonal antibodies (mAbs) and an essential Epstein-Barr virus (EBV) protein have uncovered targets that could be exploited in designing treatments and vaccines for this extremely common virus.

13 Mar 2024

Belfast Based Bia Analytical Ltd. Announce Release of Portable Testing Solution

Bia Analytical are excited to announce the launch of their much anticipated and ground-breaking new portable authenticity testing service that will offer customers a high-speed, effortless, authenticity screening at the point of sampling, bringing testing out of the lab and into the supply chain.

13 Mar 2024