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Scientists Forge a Path to the World’s First Synthetic Yeast Genome

Researchers crafted a chromosome entirely from the ground up, paving the way for the creation of the inaugural synthetic yeast in the world.

9 Nov 2023

SPT5 Identified as a Potential Target Protein for Treatment of MYC-Dependent Cancers

MYC proteins play an important role in many types of cancer. A research team at the University of Würzburg has now succeeded in indirectly influencing these proteins - with clear consequences for the tumor.

8 Nov 2023

Unlocking the Secrets of Bacterial Transcription

Bacterial transcription serves as an assembly line for duplicating genetic directives from double-stranded DNA into RNA molecules.

7 Nov 2023

Rising Prevalence of Chronic Rhinosinusitis in Japan: Causes and Implications

Chronic rhinosinusitis (CRS) is an inflammatory condition affecting the nasal cavity and sinuses, which can be categorized into eosinophilic and non-eosinophilic subtypes.

7 Nov 2023

Unveiling the Role of Foxp3 in Shaping Chromatin Architecture of Regulatory T Cells

Regulatory T cells, or Tregs, represent a specialized class of immune cells dedicated to quelling immune responses and safeguarding the body against self-attack.

7 Nov 2023

Epidemiology and Genetic Underpinnings of Clonal Hematopoiesis

A comprehensive new study from deCODE genetics, a subsidiary of Amgen, published today in Nature Genetics, provides insights into the epidemiology and somatic and germline genetics of clonal hematopoiesis.

7 Nov 2023

Epigenetic Changes Drive Cancer Development

Every cell makes its own proteins by accessing the genetic information on its genes. Changes in this information, called mutations, may ruin the function of the affected proteins.

7 Nov 2023

Researchers Enhance CAR-T Cell Therapy by Preventing T-Cell Exhaustion

CAR-T cell therapy is a last hope for many patients with blood, bone marrow or lymph gland cancer when other treatments such as chemotherapy are unsuccessful.

7 Nov 2023

Novel Gene Therapy Targets Core Motor Symptoms of Parkinson’s Disease

A team of researchers from the Shenzhen Institute of Advanced Technology (SIAT) at the Chinese Academy of Sciences (CAS) and their collaborators have devised a gene therapy approach aimed at selectively manipulating the affected circuitry in Parkinson’s disease.

6 Nov 2023

Dendritic Cells Reprogram Their Genes to Enhance Immune Response

Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), under the leadership of Professor Francisco Sánchez-Madrid, have discovered that dendritic cells, responsible for triggering targeted immune responses, possess the ability to modify their genes in order to enhance their immune reactivity.

6 Nov 2023

New Technique Unveils the Secrets of Osmotic Pressure in Living Organisms

In order to survive, organisms must control the pressure inside them, from the single-cell level to tissues and organs.

6 Nov 2023

Fetal Kidney Atlas Sheds Light on Disease Origins and Kidney Health

Scientists have examined the gene expression patterns of single cells from 5 human fetal kidneys to create the most complete atlas of the fetal kidney to date.

6 Nov 2023

CRISPR-Cas9 Enzyme's Magnesium Role Unraveled in DNA Cutting

The gene-editing technology known as CRISPR has led to revolutionary changes in agriculture, health research and more.

6 Nov 2023

Nucleotide Metabolite Controls DNA Repair and Cancer Sensitivity

Scientists have unraveled the mechanism by which a particular metabolite regulates DNA repair activity and the susceptibility of tissues to cancer treatment.

3 Nov 2023

Scientists Uncover New Insights into Cellular Recycling Process

Recycling is just as essential in cells as in our more familiar macroscopic world. Cells continuously generate waste products and accumulate damaged components while performing regular functions.

3 Nov 2023

Research Reveals How Gut Bacteria Influence Distant Organs Through Oxytocin Signaling

The gut microbiome, a community of trillions of microbes living in the human intestines, has an increasing reputation for affecting not only gut health but also the health of organs distant from the gut.

3 Nov 2023

New Study Sheds Light on Evolution of Sex Differences in Animals

Researchers at the Francis Crick Institute and Heidelberg University in Germany have shown that sex differences in animals vary dramatically across species, organs and developmental stages, and evolve quickly at the gene level but slowly at the cell type level.

3 Nov 2023