Bone Marrow News and Research

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Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

Researchers develop novel technique to monitor remote immune mechanisms

The human immune system works hard to maintain an individual’s health and protect against viruses, bacteria, parasites, fungi, and cancerous cells.

17 Dec 2021

Researchers regenerate cartilage using novel protein fragment

The existing methods for the regeneration of injured cartilage generate tissue that breaks down. This deterioration eventually leads to osteoarthritis—the commonly seen form of arthritis—affecting over 32.5 million grown-ups in the United States, as per the Centers for Disease Control and Prevention.

13 Dec 2021

Immune cells utilize the body’s fat stores to combat infection, says study

A recent study carried out by the University of East Anglia and Quadram Institute shows how immune cells utilize the body’s fat stores to combat infection.

9 Dec 2021

Next-generation sequencing for minimal residual disease proven more sensitive than flow cytometry

In pediatric and young adult patients with acute lymphoblastic leukemia (ALL) treated with tisagenlecleucel (Kymriah), DNA sequencing-based detection of residual disease between three and 12 months accurately identified all patients who would eventually relapse, while other methods were less predictive.

2 Dec 2021

Research could help understand DCIR's role in the pathogenesis of autoimmune diseases

While dendritic cell immunoreceptor (DCIR) is known to mediate inflammation and bone metabolism, ligands that bind DCIR and the mechanisms underlying DCIR activity remain poorly understood.

From Tokyo University of Science 25 Nov 2021

New 3D map provides precise locations of blood vessels and stem cells in a a mouse skull

Johns Hopkins Medicine scientists have used glowing chemicals and other techniques to create a 3D map of the blood vessels and self-renewing "stem" cells that line and penetrate a mouse skull.

19 Nov 2021

Using a new genetic technology to decipher intratumoral heterogeneity

Even within a single patient with cancer, there is a vast diversity of individual tumor cells, which display distinct behaviors related to growth, metastasis, and responses to chemotherapy.

12 Nov 2021

New approach to cut off cancer cells’ food supply and kill them

Inositol is a sugar required for cells to survive. Most cells either get it from the bloodstream or make it themselves. Since there is plenty of inositol available, some cancer cells decide to stop making it.

28 Oct 2021

Pioneering gene therapy has long-lasting effects on children with deadly immune disorder

Over a decade ago, UCLA physician-scientists began using a pioneering gene therapy they developed to treat children born with a rare and deadly immune system disorder. They now report that the effects of the therapy appear to be long-lasting, with 90% of patients who received the treatment eight to 11 years ago still disease-free.

18 Oct 2021

Scientists show how skin T cells can damage other organs in stem cell transplant patients

More than 40,000 allogeneic hematopoietic stem cell transplants are carried out worldwide every year, mostly for patients suffering from leukemia or other diseases of the hematopoietic system.

15 Oct 2021

New technology efficiently delivers immune checkpoint inhibitors for treating brain tumors

Multi-institutional researchers have succeeded in efficiently delivering an immune checkpoint inhibitor (ICI) into the mouse brain, confirming its high efficacy and specificity in treating orthotopically transplanted mice with glioblastoma (GBM). The research was published in Nature Biomedical Engineering.

12 Oct 2021

$Mesenchymal stem cells with enhanced fracture healing abilities identified$

Mesenchymal stem cells with enhanced fracture healing abilities identified

Mesenchymal stem cells (MSCs) are anticipated to harbor great potential in the area of regenerative medicine, which aims at restoring damaged tissues.

8 Oct 2021

Study explores molecular mechanism behind cell homing

Research reveals how stem cells slow down their rolling inside the circulatory system by developing long tethers that bind to the inner surfaces of blood vessels.

8 Oct 2021

Study sheds light on blood and immune systems development in prenatal bone marrow

Researchers carried out the first extensive investigation of the formation of the blood and immune systems in the prenatal bone marrow.

4 Oct 2021

Delta opioid receptor agonists modulate immune responses to ameliorate colonic inflammation

Opioids are a class of substances that control sensations such as pain and emotions in animals. While plant-derived opioid narcotics such as morphine are the most well-recognized, other opioid molecules like endorphins can also be synthesized by the body or artificially developed in laboratories.

From Tokyo University of Science 1 Oct 2021

Bone Marrow News and Research

Researchers develop novel technique to monitor remote immune mechanisms

Researchers regenerate cartilage using novel protein fragment

Immune cells utilize the body’s fat stores to combat infection, says study

Next-generation sequencing for minimal residual disease proven more sensitive than flow cytometry

Research could help understand DCIR's role in the pathogenesis of autoimmune diseases

New 3D map provides precise locations of blood vessels and stem cells in a a mouse skull

Using a new genetic technology to decipher intratumoral heterogeneity

New approach to cut off cancer cells’ food supply and kill them

Pioneering gene therapy has long-lasting effects on children with deadly immune disorder

Scientists show how skin T cells can damage other organs in stem cell transplant patients

New technology efficiently delivers immune checkpoint inhibitors for treating brain tumors

Mesenchymal stem cells with enhanced fracture healing abilities identified

Study explores molecular mechanism behind cell homing

Study sheds light on blood and immune systems development in prenatal bone marrow

Delta opioid receptor agonists modulate immune responses to ameliorate colonic inflammation

Study pinpoints means to restore the efficacy of drugs for acute myeloid leukemia

Changes in epigenome responsible for reduced stem cell function upon aging

New Cornell study finds potential treatment for MRSA ‘superbug’

Stem cell transplantation leaves no scars in the DNA of transplanted cells

Study reveals how two separate DNA changes may predict aggressive childhood leukemias

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