RNA Sequencing News and Research

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Deciphering the Tumor Microenvironment with Spatial Transcriptomics

Spatial transcriptomics (ST) has emerged as a crucial technique for mapping gene expression across tissue sections while preserving vital locational data, setting it apart from traditional methods like bulk or single-cell RNA sequencing.

30 Nov 2023

New Method Removes Background Noise from CITE-Seq Data

Researchers from the Chobanian & Avedisian School of Medicine and the College of Arts & Sciences at Boston University have devised an innovative tool to address this limitation. This tool can discern and eliminate undesirable background noise originating from various sources, enhancing the precision of analysis in CITE-seq experiments.

20 Nov 2023

More Genes Changed By Early Life Stress Than Head Injury

Researchers recently discovered a phenomenon as they delved into the investigation of whether early-life stress exacerbates the impact of a childhood head injury on health and behavior in later years.

16 Nov 2023

New Insights Into Tumor-Immune Interactions Could Lead to More Effective Therapies for Multiple Myeloma

A multicenter study led by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine shows how interactions between tumor cells and immune components of the microenvironment can impact treatment responses and outcomes in patients newly diagnosed with multiple myeloma who undergo combination treatments that include targeted immunotherapy.

10 Nov 2023

Unlocking the Secrets of Memory: Key Protein Regulates Hippocampal Plasticity

Mount Sinai researchers have shed valuable light on the mechanism of a key protein that regulates the plasticity and function of the hippocampus, a key brain region involved in memory and learning, and that decreases with age in mice.

3 Nov 2023

Developing New Strategies for Soybean Molecular Breeding

The soybean (Glycine max) stands as a significant economic crop, offering valuable resources such as edible oil, plant-based protein, and various essential nutrients for human consumption.

31 Oct 2023

Developing Regenerative Therapies to Treat Neurological Conditions

The primary cells that make up our brain and spinal cord, called neurons, are among the slowest to heal after injury, and many neurons never fully recover. Although research into neural regeneration has advanced, it is still unclear why certain neurons recover while others do not.

17 Oct 2023

New Atlases Reveal Unprecedented Detail of the Human Brain

In two concurrent projects, scientists at the Karolinska Institutet have played a significant role in producing the most extensive atlases of human brain cells to date.

13 Oct 2023

Lactate Oxidase Nanocapsules Help the Immune System to Fight and Kill Solid Tumors

UCLA researchers have developed a new treatment method using a tiny nanocapsule to help boost the immune response, making it easier for the immune system to fight and kill solid tumors.

13 Oct 2023

DNA Aptamer Promotes Cardiomyocyte Differentiation From Pluripotent Stem Cells

Generating specific cell lineages from induced pluripotent stem cells and embryonic stem cells is the holy grail of regenerative medicine.

12 Oct 2023

Study Highlights Cellular and Molecular Characteristics of Senescent Ocular Surface Cells

A new priority research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 18, entitled, "Gene expression signatures of human senescent corneal and conjunctival epithelial cells."

4 Oct 2023

Leishmania Parasites Found to Infect Non-Immune Cells

The organisms that cause visceral leishmaniasis, a potentially deadly version of the parasitic disease that most often affects the skin to cause disfiguring disease, appear to have a secret weapon, new research suggests: They can infect non-immune cells and persist in those uncommon environments.

4 Oct 2023

New Insights Into the Gibberellin Biosynthesis Pathway in Liverworts

When life gets tough, nature usually finds a way to help the little guys.

4 Oct 2023

Ribo-seq Optimization to Gain Insights into Protein Production

Ribosome profiling, a gene sequencing approach, has increased the understanding of the human genome by uncovering previously undiscovered protein-coding regions.

22 Sep 2023

Towards A Better Understanding of Early Human Embryonic Development

Despite being an essential developmental process, the understanding of human embryonic genome activation is limited, owing to the lack of in vitro cell models and ethical concerns.

22 Sep 2023

The Intriguing Phenomenon of Cellular Reprogramming

A fascinating phenomenon of cellular reprogramming in developed adult organs has been revealed by researchers, providing insight into a brand-new process of adaptive development.

12 Sep 2023

Scale Biosciences Continues Commercial Expansion with Introduction of New and Differentiated Single Cell Methylation and Single Cell RNA Sequencing Solutions

Scale Biosciences, Inc. (ScaleBioTM), an innovator in single cell sequencing leveraging combinatorial indexing technologies, today announced an expansion of their product portfolio to enable a broader range of single cell omics experiments and unlock new translational research applications.

30 Aug 2023