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New project addresses the lack of standards for optimal management of Lp(a)

According to a recent scientific statement gathered from American Heart Association, high levels of lipoprotein(a) [Lp(a)] are known to be a separate, chiefly inherited and causal risk factor for cardiovascular disease, known to be the leading cause of death and disability around the world.

29 Mar 2023

The proper implementation of stem cell-based disease models

Scientists have learned how to manufacture induced pluripotent stem cells (iPSC) from regular cells through genetic reprogramming during the last ten years.

29 Mar 2023

Determining the structure of protein pumps using cryo-EM

A rare, genetic disorder known as Hailey-Hailey disease causes patches of blisters to develop mainly in the folds of skin under the breasts, in the groin, and the armpits.

29 Mar 2023

Myeloid cells contribute to a long-lived HIV reservoir, study shows

A subset of white blood cells, known as myeloid cells, can harbor HIV in people who have been virally suppressed for years on antiretroviral therapy, according to findings from a small study supported by the National Institutes of Health.

28 Mar 2023

Human cells shed light on basic squid biology

Squids and octopuses are masters of camouflage, blending into their environment to evade predators or surprise prey.

28 Mar 2023

Finding how the global regulation factor reshapes the cell-fate-decision landscape

Determining cell differentiation trajectories has been done by genes and the regulation relationships among them creating complicated networks.

28 Mar 2023

Newest variant of mScarlet3 to help track protein movements in living cells

Biologists frequently utilize a method to figure out why a cell divides, secretes hormones, or sends a signal to another cell. They attach colored lights to the proteins of interest so that they can see their motions and interactions in living cells under a microscope.

28 Mar 2023

High-quality genome of a deep-sea eel illuminates the molecular mechanisms of deep-sea adaptation

Recently, the research team led by Dr. Shunping He from the Institute of Deep Sea Science and Engineering, Chinese Academy of Sciences, published their research findings in the online version of SCIENCE CHINA Life Sciences.

28 Mar 2023

Monocytes harbor stable HIV DNA capable of infecting neighboring cells

To develop treatments that may one day entirely rid the body of HIV infection, scientists have long sought to identify all of the places that the virus can hide its genetic code.

28 Mar 2023

Thickness of cancer cells' glycocalyx barrier determines immune cell evasion of tumors

One of the ways that cancer cells hide from the body's immune system is by forming a thin surface barrier called the glycocalyx.

27 Mar 2023

Potential therapeutic target in KRAS-mutant pancreatic cancer identified

A new research paper was published in Genes & Cancer on March 10, 2023, entitled, "VCP/p97, a pleiotropic protein regulator of the DNA damage response and proteostasis, is a potential therapeutic target in KRAS-mutant pancreatic cancer."

27 Mar 2023

Analyzing how the global regulation factor reshapes the cell-fate-decision landscape

Genes and their regulatory relationships form complex networks that govern cell differentiation trajectories. However, predicting and understanding cell fate decisions using bottom-up network topology is still side-lined.

27 Mar 2023

Key gene involved in crop alkaline tolerance discovered

Chinese scientists have identified a key gene involved in crop alkaline tolerance that may greatly improve crop yield in sodic environments through the use of genetic engineering.

24 Mar 2023

New findings could help target the causes of aging and cancer development

A protein complex prevents the repair of genome damage in human cells, in mice and in the nematode Caenorhabditis elegans, a team of researchers at the University of Cologne has discovered.

24 Mar 2023

Innovative new approach to constructing a nose in young patients with arhinia

Congenital arhinia (meaning patients born without a nose) is a rare condition associated with high mortality if not identified.

24 Mar 2023

Using AI to screen for genetic mutations in cancerous brain tumors in under 90 seconds

Using artificial intelligence, researchers have discovered how to screen for genetic mutations in cancerous brain tumors in under 90 seconds -; and possibly streamline the diagnosis and treatment of gliomas, a study suggests.

24 Mar 2023

Brain scans link signs of cellular aging to symptoms of Alzheimer’s

According to a new study led by Anya Topiwala of Oxford Population Health, a division of the University of Oxford in the United Kingdom, and published on March 22nd, 2023 in the open-access journal PLOS ONE, changes in the brain caused by Alzheimer’s disease are connected to telomeres shortening, the protective caps on the ends of chromosomes that shorten as cells age.

23 Mar 2023