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Scientists find how cells remain dormant for years before awakening to create metastatic cancer

Mount Sinai researchers have solved a major mystery in cancer research: How cancer cells remain dormant for years after they leave a tumor and travel to other parts of the body, before awakening to create metastatic cancer.

14 Dec 2021

Study suggests dietary intake of flavan-3-ols could help prevent obesity

In cold conditions, brown adipose tissue (BAT) or brown fat generates heat to keep the body warm. Compared with white adipose tissue, BAT has more mitochondria-;subcellular organelles associated with energy production-;which allows it to burn calories and produce heat by activating the mitochondrial uncoupling protein 1 (Ucp-1).

14 Dec 2021

Researchers identify toxic senescent cells in the brain as potential target for Alzheimer’s treatment

For the first time, scientists have identified a rare population of potentially toxic senescent cells in human brains that can serve as a target for a new Alzheimer's disease treatment.

13 Dec 2021

Infant's immune system may be better than the adult immune system

As any parent knows, infants are prone to getting respiratory infections. But a new study shows that the infant immune system is stronger than most people think and beats the adult immune system at fighting off new pathogens.

13 Dec 2021

High-risk lymphoma patients may receive durable benefit from axi-cel CAR T cell therapy

Three clinical studies led by researchers at The University of Texas MD Anderson Cancer Center demonstrated enhanced responses for patients with high-risk lymphoma treated with axicabtagene ciloleucel (axi-cel) chimeric antigen receptor (CAR) T cell therapy.

13 Dec 2021

Research describes dynamic genomic landscape of tumor heterogeneity in hepatocellular carcinoma

Clinician scientists and scientists from the National Cancer Centre Singapore and A*STAR's Genome Institute of Singapore, in collaboration with Singapore General Hospital, the National University Health System, Duke-NUS Medical School, Nanyang Technological University, and collaborators from China, Malaysia, Thailand and the Philippines, have described a dynamic genomic landscape of tumour heterogeneity in hepatocellular carcinoma (HCC).

13 Dec 2021

Genetic makeup of neuroblastoma shows marked spatial and temporal variability

Tumors are heterogeneous, which means that different parts of the same tumor can be genetically distinct. This phenomenon, known as intratumor heterogeneity, is steadily gaining in significance within the field of cancer research.

13 Dec 2021

Research offers alternative cell option for organs-on-chips

Organ-on-a-chip technology has provided a push to discover new drugs for a variety of rare and ignored diseases for which current models either don't exist or lack precision. In particular, these platforms can include the cells of a patient, thus resulting in patient-specific discovery.

13 Dec 2021

Sustainable dietary habits are linked to health benefits, says study

Large population research from Lund University in Sweden has revealed that sustainable dietary habits are associated with health benefits like a decreased risk of premature death from cancer and cardiovascular disease.

13 Dec 2021

Powering the Biotechnology Revolution through Cloud R&D

In this interview, we speak to Sajith Wickramasekara, CEO and Co-Founder of Benchling, about cloud R&D and how it is powering the biotechnology revolution.

From Benchling 10 Dec 2021

New classification method divides breast cancers into 12 distinct biological groups

Researchers at UNC Lineberger Comprehensive Cancer Center have taken a major step forward in melding two key methods for studying breast cancer: one by genetic analysis and the second by looking at the architecture of cells, or their pathology.

9 Dec 2021

ASHG launches major initiative to understand, document experiences of past injustice in human genetics research

The American Society of Human Genetics today announced a major year-long initiative to understand and document experiences of past injustice, as well as progress toward justice, in the human genetics research field and the Society.

9 Dec 2021

Single-cell spatial analysis may provide information about neoadjuvant therapy for triple-negative breast cancer

A next-generation technology that allows the study of protein expression at the single-cell level and the location of the cells within the tumor microenvironment (TME) was feasible and provided information on the benefit of adding the immune checkpoint inhibitor atezolizumab (Tecentriq) to chemotherapy as neoadjuvant treatment for patients with early high-risk and locally advanced triple negative breast cancer (TNBC), according to results presented at the San Antonio Breast Cancer Symposium, held December 7-10, 2021.

8 Dec 2021

World's first metal-organic framework antibody-drug delivery system developed

It sounds like the stuff of science fiction: a man-made crystal that can be attached to antibodies and then supercharge them with potent drugs or imaging agents that can seek out diseased cells with the highest precision, resulting in fewer adverse effects for the patient.

8 Dec 2021

Clinical News and Research

Scientists find how cells remain dormant for years before awakening to create metastatic cancer

Study suggests dietary intake of flavan-3-ols could help prevent obesity

Researchers identify toxic senescent cells in the brain as potential target for Alzheimer’s treatment

Infant's immune system may be better than the adult immune system

High-risk lymphoma patients may receive durable benefit from axi-cel CAR T cell therapy

Research describes dynamic genomic landscape of tumor heterogeneity in hepatocellular carcinoma

Genetic makeup of neuroblastoma shows marked spatial and temporal variability

Research offers alternative cell option for organs-on-chips

Sustainable dietary habits are linked to health benefits, says study

Powering the Biotechnology Revolution through Cloud R&D

New classification method divides breast cancers into 12 distinct biological groups

ASHG launches major initiative to understand, document experiences of past injustice in human genetics research

Single-cell spatial analysis may provide information about neoadjuvant therapy for triple-negative breast cancer

World's first metal-organic framework antibody-drug delivery system developed

New strategy to improve the therapeutic efficacy of liver cancer immunotherapy

Researchers identify protein that promotes wound healing and repair

Lunaphore to host inaugural Spatial Biology Week™ virtual meeting

Cancer drug effective against Alzheimer’s disease, says research

New nanoparticle adjuvant could lead to more powerful vaccines

Integration of digital and molecular data could enable individualized prevention of disease

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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