Drugs News and Research

RSS

Study could help develop peptide siRNA carrier for human oral cancer

MUSC Hollings Cancer Center researchers are exploring the use of peptide carriers for the delivery of small RNA drugs as a novel treatment for cancer. The team's recent work, published online March 19 in the Molecular Therapy - Nucleic Acids journal, lays the foundation for developing a clinically relevant peptide carrier RNAi-based drug treatment strategy for human oral cancer.

25 May 2021

“Paralyzed” immune cells can be reactivated by drugs in IDH-mutant gliomas

Brain tumor cells with a certain common mutation reprogram invading immune cells. This leads to the paralysis of the body's immune defense against the tumor in the brain. Researchers from Heidelberg, Mannheim, and Freiburg discovered this mechanism and at the same time identified a way of reactivating the paralyzed immune system to fight the tumor.

25 May 2021

Single fingerprint can help determine whether someone has touched or ingested class A drugs

A research team explains how they were able to distinguish between the fingerprints of those who handled cocaine with those who have taken the medicine.

From University of Surrey 20 May 2021

New technology improves efficacy of inflammatory bowel disease drugs

More Canadians suffer from inflammatory bowel disease (IBD) than anywhere else in the world, yet current treatments often have debilitating side effects and are not always effective.

20 May 2021

Study: Turning off molecular switch could help treat melanoma

Melanoma accounts for only about 1% of skin cancers but leads to most of the skin cancer-related deaths.

20 May 2021

New, patented method helps drugs to easily enter the cells

A new technique known as Progressive Mechanoporation allows genes or drugs to enter cells by mechanically disrupting cell membranes for a brief period.

13 May 2021

Study shows metabolic pathways by which Mycobacterium tuberculosis consumes its favorite nutrients

Mycobacterium tuberculosis is remarkable because it can live in the human host for decades.

From University of Surrey 13 May 2021

New drug-like compound designed to stop malaria in its tracks

Researchers at the Francis Crick Institute and the Latvian Institute of Organic Synthesis have designed a drug-like compound which effectively blocks a critical step in the malaria parasite life cycle and are working to develop this compound into a potential first of its kind malaria treatment.

13 May 2021

An efficient automated method for production of synthetic DNA

Chemically synthesized short DNA sequences are extremely important ingredients with countless uses in research laboratories, hospitals, and in industry, like in the method for identifying COVID-19.

13 May 2021

Study: Individuals who recovered from depression had increased level of serotonin transporter

Low levels of serotonin in the brain are seen as a possible cause of depression and many antidepressants act by blocking a protein that transports serotonin away from the nerve cells.

11 May 2021

Newly designed higher affinity monoclonal antibody for cancer treatment

Recently, Prof. XIE Can from the High Magnetic Field Laboratory of the Hefei Institutes of Physical Science (HFIPS), in a collaboration with Prof. YAN Xiyun's lab from the Institute of Biophysics, reported the structural basis of mAb AA98's inhibition on CD146-mediated endothelial cells (EC) activation and designed higher affinity monoclonal antibody HA98 for cancer treatment.

10 May 2021

Study defines genetic positions associated with the progression of Parkinson’s disease

The progression of Parkinson’s disease (PD) is an important factor in patients’ well-being and clinical trials.

7 May 2021

Study reveals a compound found in avocados helps in the treatment of leukemia

According to recent research at the University of Guelph, a compound found in avocados may one day lead to improved leukemia treatment.

4 May 2021

Researchers devise a small-molecule cocktail to protect stem cells from stress

Researchers at the National Institutes of Health (NIH) have devised a four-part small-molecule cocktail that can protect stem cells called induced pluripotent stem cells (iPSCs) from stress and maintain normal stem cell structure and function.

4 May 2021

New therapeutic target for patients with acute myeloid leukemia

According to a new study, targeting a pathway that is critical for the survival of some cases of acute myeloid leukemia could open up a new therapeutic route for patients.

3 May 2021

Genetically encoded sensor helps detect hallucinogenic substances

Researchers at the University of California, Davis, have created a genetically encoded sensor for detecting hallucinogenic substances.

From The University of California, Davis 29 Apr 2021

Increased expression of DUSP16 molecule leads to cancer chemoresistance

Chemotherapy is a drug treatment that uses powerful chemicals to kill fast-growing cancer cells in the body. It is a systemic treatment where drugs travel throughout the body and destroy cancer cells that have spread (metastasized) to parts of the body far away from the original (primary) tumour.

28 Apr 2021