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The Function of Stem Cell Barriers in the Treatment of Fertility

A set of molecules controls cells as they proliferate and take on certain identities and spatial placements within a human embryo as it develops.

18 Jul 2023

Berkeley Lab and Genentech Team Up to Develop Next-Generation Drug Delivery System

Many diseases can be successfully treated in the simple environment of a cell culture dish, but to successfully treat real people, the drug agent has to take a journey through the infinitely more complex environment within our bodies and arrive, intact, inside the affected cells.

18 Jul 2023

New Study Identifies Aerobic Glycolysis Vital for Eye Development

According to a recent Northwestern Medicine study published in Nature Communications, aerobic glycolysis, the process by which cells convert glucose into lactate, is essential for eye development in mammals.

17 Jul 2023

New Insights into the Regulatory Network of Th17 Cells

N6-methyladenosine (m6A) is the most extensively studied RNA modification across multiple species, and its importance in the immune system has been demonstrated in a variety of contexts, including mRNA metabolism, cell differentiation, proliferation, and response to stimulation.

17 Jul 2023

Extrusion-Mediated Self-Renewal: A New Way for Kidney Cells to Stay Healthy

University of Texas at Dallas scientists have discovered a previously unknown "housekeeping" process in kidney cells that ejects unwanted content, resulting in cells that rejuvenate themselves and remain functioning and healthy.

14 Jul 2023

New Simulations Reveal How Nuclear Pore Complex Regulates Protein Trafficking

If the human cell is a nightclub, then the nucleus is a VIP lounge. Inside are the DNA, fiercely maintained by the nuclear pore complex, which is charged with the task of protecting every strand. To do this, the NPC acts as gatekeeper against unworthy proteins.

14 Jul 2023

New P38 Inhibitors Selectively Target Cardiac Cell Death

The p38 protein regulates a wide variety of cellular functions and is related to diseases such as chronic inflammation, immunological disorders, or cancer.

14 Jul 2023

Metabolic Systems Share Previously Unknown Universal Properties: Study

A team from the University of Tokyo has combined economic theory with biology to understand how natural systems respond to change. The researchers noticed a similarity between consumers' shopping behavior and the behavior of metabolic systems, which convert food into energy in our bodies. The team focused on predicting how different metabolic systems might respond to environmental change by using an economic tool called the Slutsky equation.

14 Jul 2023

Novel Drug Compound Reduces Sensory Hypersensitivity in Fragile X Mice

Boosting the activity of inhibitory interneurons in Fragile X mice reduced their hypersensitivity to sensory stimuli, according to a new Neuron study led by UCLA Health researchers.

14 Jul 2023

Revealing the Function of Retrotransposons

A retrotransposon, a parasitic DNA sequence that borrows the cell’s own machinery to accomplish its objectives, has been discovered.

13 Jul 2023

Mast Cells May Help Humans Avoid Harmful Antigens

Mast cells, which are part of the immune system, are still a puzzle. Mast cells function as a sensor that signifies the animals to avert antigens, including harmful allergens, and thus safeguard themselves from health-threatening inflammatory reactions, according to researchers at the German Cancer Research Center (DKFZ). The research was published in the journal Nature.

13 Jul 2023

New Approach to Reverse Aging and Restore Cellular Function

Researchers have opened a new front in the battle against aging and diseases associated with old age through a ground-breaking study

13 Jul 2023

The Future of Nanobiotechnology: Ethical Considerations

Prosthetics moved by thoughts. Targeted treatments for aggressive brain cancer. Soldiers with enhanced vision or bionic ears.

13 Jul 2023

Exploring How Molecules Organize in Cells

Large, complex molecules crowd the inside of a living cell. Recent research into how these molecules instantaneously organize themselves could assist in understanding how cells manage their vital biochemistry in a crowded environment.

12 Jul 2023

Dad’s Genes “Remote Control” Mom’s Metabolism to Benefit Fetus

The unborn baby “remote controls” its mother’s metabolism, resulting in a nutritional tug-of-war between the two. The mother’s body requires the baby to survive, but she also needs enough glucose and fats in her system to be able to deliver the baby, breastfeed, and reproduce again.

12 Jul 2023

First 'Living Digital Camera' Stores Images in DNA

In a world first, a 'biological camera' bypasses the constraints of current DNA storage methods, harnessing living cells and their inherent biological mechanisms to encode and store data.

12 Jul 2023

The Mechanism of Immune Memory Development

The memory of the immune system depends on distinctive epigenetic traits and a particular 3D arrangement of the DNA in the nucleus of memory cells, allowing for rapid activation of these cells, according to a team of researchers from the Erasmus University Medical Center, the Centre for Genomic Regulation (CRG), and the Josep Carreras Leukaemia Research Institute.

12 Jul 2023

New Insights Into How Genes Are Activated

Genetic information contained within DNA has to be read by specific proteins that enable the process of gene activation to begin – but in many cases, these proteins can't access their targets because DNA strands are bundled up to control what genes are used in the wide range of different cell types.

12 Jul 2023

Glucose-Sensing Neurons May Play a Role in Regulating Blood Sugar

The body's blood glucose level needs to be maintained in a relatively narrow range. It cannot be too high, as it can lead to diabetes, and it cannot be too low because it can cause fainting or even death.

12 Jul 2023

Revolutionizing Drug Design with Light-Activated Molecular Machines

Cells “talk” to one another to coordinate crucial biological activities such as immune activation, muscle contraction, hormone release, neuronal firing, and digestion using calcium signaling as a primary mechanism.

11 Jul 2023