Coronavirus News and Research

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Antibodies may not inhibit SARS-CoV-2 variants from minks

It has been known for about a year that minks can become infected with SARS-CoV-2. The virus had been transmitted from humans to farmed mink and mutated in infected animals. Mutations were acquired in the spike protein, which is crucial for the entry of the virus into host cells and represents the central point of attack for antibodies.

20 Apr 2021

Chemical biomarker levels reflect varying severity of COVID-19 symptoms

Varying severity of COVID-19 symptoms in patients is reflected by levels of a chemical biomarker in their body which scientists say could be used to better manage treatments and other interventions, including vaccinations.

20 Apr 2021

Researchers take a key step toward new drugs and vaccines for combating COVID-19

Scientists have achieved a huge step toward new vaccines and drugs for fighting against COVID-19.

6 Apr 2021

Low K777 concentrations inhibit cathepsin L and reduce SARS-CoV-2’s ability to infect host cell lines

For a long time, James McKerrow, MD, PhD, dean of the Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego, has investigated neglected tropical diseases, which are chronic, disabling parasitic infections mainly affecting the poor and underserved communities in developing nations.

From UC San Diego 5 Apr 2021

B.1.1.7 variant of SARS-CoV-2 spreading quickly in the United States

The faster-spreading B.1.1.7 variant of SARS-CoV-2 first detected in the United Kingdom, the coronavirus that causes COVID-19, is quickly on its way to becoming the dominant variant of the virus in the United States, according to a study from scientists at Scripps Research and the COVID-19 test maker Helix.

31 Mar 2021

Salivary gland cells could play role in SARS-CoV-2 virus transmission

Scientists have shown that SARS-CoV-2, the virus that causes COVID-19, can infect specific cells in the salivary gland in the mouth.

26 Mar 2021

Antibody used for COVID-19 therapy can no longer inhibit new SARS-CoV-2 variants

Cell culture studies show that mutated viruses are less susceptible to inhibition by antibodies from recovered or vaccinated individuals.

26 Mar 2021

Hormone drugs may help disarm coronavirus spike protein and stop disease progression

Hormone drugs that reduce androgen levels may help disarm the coronavirus spike protein used to infect cells and stop the progression of severe COVID-19 disease, suggests a new preclinical study from researchers in the Abramson Cancer Center at the University of Pennsylvania and published online in Cell Press's iScience.

23 Mar 2021

Study shows how human viruses are better adapted to infect certain tissues

The world’s first systematic study has explained how SARS-CoV-2 and other human viruses are more adapted to infect specific types of tissues..

17 Mar 2021

Study on AEG12 mosquito protein could lead to therapeutics against deadly viruses

Researchers have found that AEG12, a mosquito protein, strongly suppresses the class of viruses causing dengue, yellow fever, Zika, and West Nile.

11 Mar 2021

Face masks made of cotton fabrics work best to slow down the spread of COVID-19

Researchers have come up with a better way to test which fabrics work best for masks that are meant to slow the spread of COVID-19.

From National Institute of Standards and Technology (NIST) 10 Mar 2021

New sensor can rapidly detect RNA and DNA molecules

According to a new study, a tiny sensor used in brain chemistry research can rapidly identify the crucial molecules that offer the genetic instructions for life.

5 Mar 2021

Mutant peptides derived from SARS-CoV-2 hamper activation of CD8+ killer T cells

A deep sequencing study of 747 SARS-CoV-2 virus isolates has revealed mutant peptides derived from the virus that cannot effectively bind to critical proteins on the surface of infected cells and, in turn, hamper activation of CD8+ killer T cells that recognize and destroy these infected cells.

5 Mar 2021

New ways proposed to overcome barriers in COVID-19 response

An international research team is calling for better consolidation of bioinformatics, viral genetics, and public health to allow for better pandemic responses.

5 Mar 2021

New approach could speed the search for promising therapies

Assessing a drug compound by its activity, not simply its structure, is a new approach that could speed the search for COVID-19 therapies and reveal more potential therapies for other diseases.

2 Mar 2021

Innovative system allows complete study of SARS-CoV-2 mutant spectrum by ultrasequencing

Researchers have designed a program that allows the complete study of the SARS-CoV-2 mutant spectrum by ultrasequencing.

15 Feb 2021

Researchers identify protein sequences that might be used by SARS-CoV-2 to infect cells

Researchers at EMBL Heidelberg have identified sequences in human proteins that might be used by SARS-CoV-2 to infect cells. They have discovered that the virus might hijack certain cellular processes, and they discuss potentially relevant drugs for treating COVID-19.

12 Feb 2021

Seasonal human coronavirus antibodies not associated with protection against SARS-CoV-2

Past exposure to seasonal coronaviruses (CoVs), which cause the common cold, does not result in the production of antibodies that protect against the novel coronavirus SARS-CoV-2, according to a study led by Scott Hensley, PhD, an associate professor of Microbiology at the Perelman School of Medicine at the University of Pennsylvania.

11 Feb 2021

Climate change may have played a direct role in the emergence of SARS-CoV-2

Global greenhouse gas emissions over the last century have made southern China a hotspot for bat-borne coronaviruses, by driving growth of forest habitat favored by bats.

8 Feb 2021

Researchers propose new technique to detect SARS-CoV-2

SARS-CoV-2 infects human beings by attaching its surface-exposed spike proteins to ACE2 receptors, which in turn, are exposed on the cell membranes.

5 Feb 2021

Coronavirus News and Research

Antibodies may not inhibit SARS-CoV-2 variants from minks

Chemical biomarker levels reflect varying severity of COVID-19 symptoms

Researchers take a key step toward new drugs and vaccines for combating COVID-19

Low K777 concentrations inhibit cathepsin L and reduce SARS-CoV-2’s ability to infect host cell lines

B.1.1.7 variant of SARS-CoV-2 spreading quickly in the United States

Salivary gland cells could play role in SARS-CoV-2 virus transmission

Antibody used for COVID-19 therapy can no longer inhibit new SARS-CoV-2 variants

Hormone drugs may help disarm coronavirus spike protein and stop disease progression

Study shows how human viruses are better adapted to infect certain tissues

Study on AEG12 mosquito protein could lead to therapeutics against deadly viruses

Face masks made of cotton fabrics work best to slow down the spread of COVID-19

New sensor can rapidly detect RNA and DNA molecules

Mutant peptides derived from SARS-CoV-2 hamper activation of CD8+ killer T cells

New ways proposed to overcome barriers in COVID-19 response

New approach could speed the search for promising therapies

Innovative system allows complete study of SARS-CoV-2 mutant spectrum by ultrasequencing

Researchers identify protein sequences that might be used by SARS-CoV-2 to infect cells

Seasonal human coronavirus antibodies not associated with protection against SARS-CoV-2

Climate change may have played a direct role in the emergence of SARS-CoV-2

Researchers propose new technique to detect SARS-CoV-2

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