Neurodegeneration News and Research

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Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons.

'Fat burning' molecule holds promise for future treatment and prevention of obesity

Obesity affects more than 40 percent of adults in the United States and 13 percent of the global population.

9 Jun 2020

Stem cell model sheds new light on neurodegeneration process

A new study published today in Neuron led by The New York Stem Cell Foundation Research Institute's Valentina Fossati, Ph.D., creates astrocytes - an integral support cell in the brain - from stem cells and shows that in disease-like environments, these normally helpful cells can turn into neuron-killers.

2 Jun 2020

Study highlights crucial role of immune-system molecule in Huntington's disease

More than a decade before people with Huntington's disease show symptoms, they can exhibit abnormally high levels of an immune-system molecule called interleukin-6 (IL-6), which has led many researchers to suspect IL-6 of promoting the eventual neurological devastation associated with the genetic condition.

28 May 2020

Aging neurons build up DNA damage, study finds

MIT neuroscientists have discovered that an enzyme called HDAC1 is critical for repairing age-related DNA damage to genes involved in memory and other cognitive functions.

18 May 2020

Hyperosmotic stress induces phase separation of the proteasomes

Cellular proteostasis is regulated by a crucial proteolytic machine called proteasome via selective degradation of ubiquitylated proteins.

29 Apr 2020

New method for mapping the structures of heparan sulfate sugars

Heparin, the blood-thinning drug, is used worldwide. However, to date, mapping of the fundamental sugar structures of heparin and the wider class of heparan sulfate sugars in cells has not been accomplished.

23 Mar 2020

Hero proteins can prevent dangerous clumps linked with neurodegenerative diseases

At the University of Tokyo (UTokyo), scientists have identified a new group of proteins that have been hailed for their extraordinary shape and potential to defend against protein clumps linked with neurodegenerative diseases in laboratory experiments.

13 Mar 2020