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Novel Mathematical Framework Evaluates the Dynamics of Adaptive Immune Evasion

Recent research published in the journal eLife proposes a theory for how cancer cells might actively adapt to the immune system to become resistant to immunotherapy.

27 Apr 2023

UMass Amherst Researcher Receives New Innovator Grant

Lutz Grossmann is on a scientific quest to develop tasty, animal-free protein that has a minimal carbon footprint and is generated without the use of agricultural land, which is a common and more stressed source of the world’s food supply.

27 Apr 2023

Modulation of ERK Signaling Could be Used to Stimulate Regeneration

Why do some animals regenerate lost tissues after injury while others don't? Researchers from the lab of Kerstin Bartscherer (Osnabrück University and formerly Hubrecht Institute) and Ashley Seifert (University of Kentucky) studied spiny mice, which have a remarkable regenerative capacity, to answer this question.

26 Apr 2023

New, Improved Dual Version of Living Yeast Biosensor to Detect All Peptide Variants

Biosensors-;sensors that can detect biological samples-;are powerful tools for understanding the function, composition, and structure of biochemical molecules.

26 Apr 2023

Researchers Develop 9CN-Rhodol-Based Activatable Raman Probes With High Sensitivity

Raman imaging offers a greater potential for detecting multiple enzyme activities than fluorescence imaging, demonstrate Tokyo Tech researchers by developing 9CN-rhodol-based activatable Raman probes using a novel mechanism for Raman signal activation.

26 Apr 2023

Computational Models can Help Determine the Identities and Roles of Individual Neurons

Investigators at Cedars-Sinai have created computer-generated models to bridge the gap between "test tube" data about neurons and the function of those cells in the living brain.

26 Apr 2023

Capturing Viruses in a Lipid Trap

Viruses like influenza A and Ebola invade human cells in a number of steps. In an interdisciplinary approach, research teams from Heidelberg University and Heidelberg University Hospital investigated the final stages of viral penetration using electron tomography and computer simulations.

26 Apr 2023

Membrane-Remodeling Proteins in Cyanobacteria are Similar to Protein Found in Higher Organisms

The cells of living organisms are equipped with proteins that are involved in the shaping and remodeling of cellular membranes, thereby performing important tasks.

26 Apr 2023

Previously Unknown Group of Bacteria Plays Key Role in the Ocean's Energy Cycle

A team of international researchers led by Federico Baltar of the University of Vienna and José M González of the University of La Laguna has identified a previously unknown group of bacteria, called UBA868, as key players in the energy cycle of the deep ocean.

26 Apr 2023

Green Algae in Swedish Lakes Offer New Clues to the Amazing Paths of Evolution

By studying green algae in Swedish lakes, a research team, led by Lund University in Sweden, has succeeded in identifying which environmental conditions promote multicellularity.

26 Apr 2023

A Study on Neural Crest Cell

As per a new study from the University of Bath, a neural crest cell (a kind of stem cell) starts with the capacity to differentiate into numerous specialist cell kinds, but it also seems to retain the ability to “change its mind” and differentiate again when the situations are appropriate.

26 Apr 2023

Previously Unknown Protein Reveals RNA Repair Mechanism in Humans

Ribonucleic acids (RNAs) are single-stranded molecules that are found in all living organisms’ cells. As “transcripts” of human genes, mRNAs, for instance, play a role in the translation of genetic information by bearing the instructions for the production of a protein in their own sequence.

26 Apr 2023

Interpreting Mutations in Disease Genes and Improving Clinical Decision-Making

DeMAG is a new method that was developed by Max Planck and Harvard’s research team. It is a new technique that has been shared as an open-source web server (demag.org) to assist interpret mutations in disease genes and enhance clinical decision-making.

26 Apr 2023

Generating the Landscape of m6A in a Mouse Embryo

RNA, particularly mRNA, has recently received some attention as the major component of the COVID-19 vaccines.

26 Apr 2023

Mathematical Mechanism Behind the Rugged Structures at Cell Boundaries

The mathematical and biological mechanisms underlying the rugged structures at cell boundaries present in tissues like the kidneys and nasal glands have been discovered.

26 Apr 2023

Revealing an Unanticipated Mechanism for Chaperone-Mediated Ribosome Repair

Researchers have discovered that if oxidative stress destroys protein factories known as ribosomes, repair crews may go in to assist in repairing the damage so that production may restart rapidly.

26 Apr 2023

Genetic Variants of TNFAIP3 May Protect the Kidneys from Damage

A breakthrough in gene variants of an inflammation “brake” brings researchers one step closer to developing personalized treatments for those at risk of kidney disease and kidney failure.

26 Apr 2023

Antibacterial Biologic Agent Effective Against Staphylococcus Aureus Infections in Early Tests

Researchers at NYU Grossman School of Medicine and Janssen Biotech, Inc. have shown in early tests that a bioengineered drug candidate can counter infection with Staphylococcus aureus – a bacterial species widely resistant to antibiotics and a major cause of death in hospitalized patients.

25 Apr 2023

CloneTracer Reveals a Differentiation Landscape of Acute Myeloid Leukemia

Researchers have developed a new method to distinguish between cancerous and healthy stem cells and progenitor cells from samples of patients with acute myeloid leukemia (AML), a disease driven by malignant blood stem cells that have historically been difficult to identify.

25 Apr 2023

Metabolic Network Compatibility Not Likely the Limiting Factor in Prokaryotic Endosymbiosis

"One of the great mysteries of biology," says Eric Libby, former SFI Postdoctoral Fellow, now an associate professor at the Integrated Science Lab (IceLab), Umeå University in Sweden, "is eukaryogenesis, or how eukaryotes arose." Scientists consider this to be a period of major evolutionary transition, critical to our understanding of the history and evolution of life on Earth.

25 Apr 2023

Cell News and Research

Novel Mathematical Framework Evaluates the Dynamics of Adaptive Immune Evasion

UMass Amherst Researcher Receives New Innovator Grant

Modulation of ERK Signaling Could be Used to Stimulate Regeneration

New, Improved Dual Version of Living Yeast Biosensor to Detect All Peptide Variants

Researchers Develop 9CN-Rhodol-Based Activatable Raman Probes With High Sensitivity

Computational Models can Help Determine the Identities and Roles of Individual Neurons

Capturing Viruses in a Lipid Trap

Membrane-Remodeling Proteins in Cyanobacteria are Similar to Protein Found in Higher Organisms

Previously Unknown Group of Bacteria Plays Key Role in the Ocean's Energy Cycle

Green Algae in Swedish Lakes Offer New Clues to the Amazing Paths of Evolution

A Study on Neural Crest Cell

Previously Unknown Protein Reveals RNA Repair Mechanism in Humans

Interpreting Mutations in Disease Genes and Improving Clinical Decision-Making

Generating the Landscape of m6A in a Mouse Embryo

Mathematical Mechanism Behind the Rugged Structures at Cell Boundaries

Revealing an Unanticipated Mechanism for Chaperone-Mediated Ribosome Repair

Genetic Variants of TNFAIP3 May Protect the Kidneys from Damage

Antibacterial Biologic Agent Effective Against Staphylococcus Aureus Infections in Early Tests

CloneTracer Reveals a Differentiation Landscape of Acute Myeloid Leukemia

Metabolic Network Compatibility Not Likely the Limiting Factor in Prokaryotic Endosymbiosis

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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