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Single-cell cloning can lead to new therapies for COPD

Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of death around the world. Now, two internationally acclaimed stem cell experts have discovered a large number of abnormal stem cells found in the lungs of COPD patients.

16 Apr 2020

Identifying Potential Drugs Earlier In Discovery

Scientists have developed a technique that could significantly reduce the time of discovering potential new antibody-based drugs to treat disease.

16 Apr 2020

Scientists determine first 3D structure of COVID-19 main protease

A team of Chinese scientists has reported the high-resolution crystal structure of the main protease (Mpro) of the COVID-19 virus and has identified drugs that may hold promise in combating the virus.

15 Apr 2020

Research provides new insights into building blocks of gum disease

Porphyromonas gingivalis is a major bacterial pathogen which leads to periodontitis also known as gum disease. In Japan, 80% of adults aged 35 and over suffer from this disease. What's more, P. gingivalis has also been linked to rheumatoid arthritis, cardiovascular disease, pancreatic cancer, and even Alzheimer's disease.

15 Apr 2020

Study offers insight into exchange of drug resistance genes among bacteria

Researchers have been able to identify and track the exchange of genes among bacteria that allow them to become resistant to drugs, according to a new study published today in eLife.

15 Apr 2020

Metals can affect the formation of harmful misfolded peptide clusters in various diseases

Revealing the interactions between metal ions and peptides in the body could help develop enhanced treatments for Alzheimer’s diabetes, and other diseases.

14 Apr 2020

Important genetic mechanism behind inflammatory bowel disease revealed

Researchers at Children's Hospital of Philadelphia have pinpointed a genetic variation responsible for driving the development of inflammatory bowel disease.

10 Apr 2020

Rice chemist receives NIH grant to speed up drug design

Rice University chemist László Kürti and his lab have received a prestigious Maximizing Investigators' Research grant from the National Institutes of Health to speed up drug design by simplifying the synthesis of essential precursors.

9 Apr 2020

Personalized biohybrid microrobots for therapeutic cargo delivery

Tiny biohybrid robots on the micrometer scale can swim through the body and deliver drugs to tumors or provide other cargo-carrying functions.

8 Apr 2020

Study reveals shape-shifting enzyme dihydrofolate reductase is associated with catalysis

Researchers from the University of Groningen have visualized the characteristics of a single enzyme within a nanopore.

8 Apr 2020

Scientists discover unexpected pathway by which brown fat can burn energy

When we are exposed to sufficient cold or exercise, small clusters of brown fat cells in our bodies begin to burn up energy.

7 Apr 2020

Researchers gain insight into synthesis and functions of lipids found in tears

New understandings of how lipids function within tears could lead to better drugs for treating dry eye disease.

7 Apr 2020

Study sheds light on the mechanism of cell division

There is no clear consensus on when exactly cells decide to divide. For four decades, the answer provided in the textbook was that this decision takes place in the initial phase of the existence of a cell—that is, soon after a mother cell divides into daughter cells.

7 Apr 2020

Scientists discover molecular mechanism that regulates the body's immune sentinels

A team at the Centro Nacional de Investigaciones Cardiovasculares, working in partnership with researchers at Mount Sinai Hospital in New York, has discovered a new molecular mechanism mediated by nuclear receptors that determines the identity and expansion of macrophages--one of the cell types that act as immune sentinels in the body.

6 Apr 2020

Protein Abundant In The Heart Plays Key Role In Blood Clotting

Heart protein cardiac myosin, which is released into the body when a person suffers a heart attack, can cause blood to thicken or clot.

3 Apr 2020

Researchers develop 3D cultured cells that mimic liver fibrosis

Headed by researchers from Japan-based Tokyo University of Agriculture and Technology (TUAT), a group of scientists has effectively established three-dimensional (3D) cultured tissue that imitates liver fibrosis, which is a major trait of non-alcoholic steatohepatitis (NASH).

2 Apr 2020

Virtual Cell Predicts How Close Tumor Environment Influences Cancer Metastasis

The process of metastasis, which allows carcinoma cells to leave the tumor of origin, is still the leading cause of mortality for cancer patients.

2 Apr 2020

Discovery Of New Biomarker In Blood Could Lead To Early Test For Alzheimer's Disease

Researchers discovered that high blood levels of RNA produced by the PHGDH gene could serve as a biomarker for early detection of Alzheimer's disease.

From UC San Diego 2 Apr 2020

Study reveals coconut oil reduces metabolic syndrome associated with obesity

An animal study has found that obese females who consumed a small amount of coconut oil every day, in spite of having a high-fat diet, exhibited reduced metabolic syndrome—several risk factors that increase the possibilities of developing heart disease, diabetes, and stroke.

1 Apr 2020

New cell therapy proves effective in human and mouse tumor models

A new study published recently in eLife reports that researchers have developed new immunotherapy that eliminates solid tumors in mice without causing detrimental side effects.

1 Apr 2020