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Emerging hydrogel material could improve delivery of oral drugs

An emerging hydrogel material with the capacity to degrade and spontaneously reform in the gastrointestinal tract could help researchers develop more effective methods for oral drug delivery.

From Lehigh University 20 Jul 2020

Researchers to develop new ways to prevent esophageal cancer

The incidence of esophageal adenocarcinoma has increased 8-fold over the past 50 years. This is one of the deadliest cancers, with a five-year survival rate of only 20 percent.

14 Jul 2020

Study shows cathepsin B can be used as biomarker for traumatic brain injury

Scientists at the Walter Reed Army Institute for Research (WRAIR) have recently demonstrated that cathepsin B, a well-studied protein important to brain development and function, can be used as biomarker, or indicator of severity, for traumatic brain injury.

14 Jul 2020

Newly synthesized peptides show promise for treating gastrointestinal disorders

Thanks to the interesting group of trefoil factor peptides, both industry and research could usher in better treatments for chronic disorders.

8 Jul 2020

Region-specific atlas reveals genome linked to human embryonic brain development

An adjusted sequence of genetic events should occur to allow the budding brain of a human embryo to turn into the organ that regulates human consciousness.

1 Jul 2020

C. difficile hijacks the wound healing system to cause serious and persistent disease

Monash University researchers have discovered that the devastating bacterial superbug Clostridioides difficile hijacks the human wound healing system in order to cause serious and persistent disease, opening up the development of new therapies to treat the disease.

26 Jun 2020

Study shows microbiome can determine the wound healing process

If individuals experience a cut on their foot or leg, how long does it take for that particular wound to reveal signs of healing?

23 Jun 2020

Softening cell's nucleus can help the body to efficiently repair injuries

By softening a cell's nucleus so that it can squeeze its way through dense connective tissues, a group of researchers believe they've demonstrated a new way to help the body efficiently repair injuries.

23 Jun 2020

Using CAR T cells to target senescence-related diseases

Chimeric antigen receptor (CAR) T cells have transformed the treatment of refractory blood cancers. These genetically engineered immune cells seek out and destroy cancer cells with precision.

19 Jun 2020

New microscope looks at the different parameters that change during wound healing

Researchers at the GSK Center for Optical Molecular Imaging have developed a new microscope that looks at the different parameters that change during wound healing. They hope to use this technique to understand how skin disorders, such as foot ulcers in diabetic patients and psoriasis, can be treated.

18 Jun 2020

Microneedle depots effectively deliver stem cells into damaged tissues

Mesenchymal stem cells are multipotent in that they naturally replenish the cell types that build our bone, cartilage and adipose tissues.

10 Jun 2020

Researchers deconstruct complex mechanisms that control tissue repair

ETH researchers have deconstructed the mechanisms that control wound healing and scar formation in more detail.

4 Jun 2020

The eye launches an immune response in the lens following injury

The lens of the eye is an unusual organ. Unlike most of the body's organs, blood vessels don't reach the lens. If they did, they'd obscure our vision and we wouldn't be able to see. The lack of vasculature led scientists to believe immune cells, which travel via the bloodstream, couldn't get to this part of the body either.

27 May 2020

Mechanically rejuvenated fibroblasts show promise in stem cell engineering

Fibroblasts synthesize the collagen, creating the structural framework for animal tissues, and play a significant role in the process of wound healing.

27 May 2020

Compounds in Brazilian shrub can reduce the virulence of antibiotic-resistant bacteria

Researchers have discovered that the Brazilian peppertree—an invasive, weedy shrub found in Florida—contains specific compounds that lower the virulence of Staphylococcus bacteria that are resistant to antibiotics.

25 May 2020

Research uncovers a novel mechanism for controlling genes

The genetic information within our cells is what makes humans unique. The cell nucleus has a complex structure that harbors this genetic information.

13 May 2020

Stem cells can postpone their own death to aid healing

Already known for their shape-shifting abilities, stem cells can now add "death-defying" to their list of remarkable qualities.

8 May 2020

Study shows how tumor cells respond to nutrient deficiency

Some solid tumors have a very high growth rate, which often leads to a lack of vascularization due to the impossibility to develop, at the same time, the blood vessels that accompany and nourish it.

22 Apr 2020

Study reveals the formation of tuft cells and their role in immunity

Chronic pancreatitis, or persistent inflammation of the pancreas, is a known risk factor that leads to the development of pancreatic cancer, which is the third-deadliest cancer in the United States.

20 Apr 2020

Stem cell strategy can help improve the effectiveness of cardiac repair

Human stem cells have been typically perceived as one of the potential cell sources for cardiac regeneration treatment. However, the substandard performance following transplantation into the failing hearts has limited their applications in clinical use.

30 Mar 2020