therapeutics News and Research

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Crick Researchers Identify Stem Cells in Thymus for First Time

For the first time, Francis Crick Institute researchers have discovered stem cells in the human thymus. These cells provide a possible new target for research into immunological disorders, cancer, and immune system stimulation.

31 Aug 2023

New Insights into MCM8/9 Enzyme Could Lead to Treatments for Infertility and Cancer

Scientific research requires patience. The rewards are not always immediate, and the technology needed does not always exist. Michael A. Trakselis, Ph.D., professor and director of graduate affairs for the Department of Chemistry and Biochemistry at Baylor University, understands this.

30 Aug 2023

Intellegens and CPI Awarded £1.6 m Innovate UK Grant to Advance Manufacture of Oligonucleotide Therapeutics with Machine Learning

Intellegens today announced that it has secured a £1.6 m grant from Innovate UK, part of UK Research and Innovation (UKRI), to apply ML in the emerging field of oligonucleotide therapies.

From Intellegens Limited 30 Aug 2023

Scientists Uncover New Mechanism for Degrading Short-Lived Proteins

Short-lived proteins control gene expression in cells to carry out a number of vital tasks, from helping the brain form connections to helping the body mount an immune defense. These proteins are made in the nucleus and are quickly destroyed once they've done their job.

25 Aug 2023

Waters Corporation and Princeton University Announce Multi-Year Research Collaboration

Waters Corporation announced a multi-year research collaboration with Princeton University that will enable scientists, faculty, and students to work together to bring their diverse skills and backgrounds to solve complex challenges in biochemistry and materials science.

From Waters Corporation 24 Aug 2023

Bioengineered Enzyme-Based Scissors can Selectively Remove Mucins Off Cancer Cells

Cancer cells can evade the body's immune defenses by exploiting a normally helpful and ubiquitous group of molecules known as mucins.

24 Aug 2023

Single Injection of CRISPR Gene-Editing Treatment Safely Removes SIV From Non-Human Primates

A single injection of a novel CRISPR gene-editing treatment safely and efficiently removes SIV – a virus related to the AIDS-causing agent HIV – from the genomes of non-human primates, scientists at the Lewis Katz School of Medicine at Temple University now report.

17 Aug 2023

Newly Developed Antibody Therapy to Have Benefits Over Existing Opioid-Overdose Treatments

An antibody in single-chain fragment variable (scFv) format that binds to the powerful opioid carfentanil was shown to reverse signs of carfentanil overdose in preclinical tests conducted by scientists at Scripps Research.

11 Aug 2023

Gene Therapy Prevents Progression of Kidney Disease in Children

Researchers at the University of Bristol have made a remarkable step forward in finding a potential cure for a type of childhood kidney disease.

11 Aug 2023

Researchers Elucidate STING Protein's New Role in Immune Defense

A signaling protein known as STING is a critical player in the human immune system, detecting signs of danger within cells and then activating a variety of defense mechanisms.

7 Aug 2023

Study Shows How Sensory Neurons Control Gastrointestinal Tracts

Gastrointestinal and digestive issues impact roughly 3 million people across the United States alone, and that number is growing.

4 Aug 2023

The Peptoid Approach to Antiviral Resistance

Antiviral therapies are difficult to develop because viruses can rapidly mutate to become drug resistant.

3 Aug 2023

New Breakthrough in Generative AI Models and AlphaFold Structures for Drug Discovery

Insilico Medicine ("Insilico"), a clinical-stage end-to-end generative artificial intelligence (AI) drug discovery company, has achieved a significant breakthrough in the application of multiple generative AI models and AlphaFold structures for drug discovery.

3 Aug 2023

Alligator Bioscience Announce Milestone Achievement in 2021 Immuno-Oncology Research Collaboration and License Agreement with Orion Corporation

Alligator Bioscience today announced that Technical Feasibility in the second program under the research collaboration and license agreement with Orion Corporation, which aims to discover and develop new bispecific antibody cancer therapeutics, has been achieved.

1 Aug 2023

RNA-Based CATCH Strategy Aims to Activate Dendritic Cells

Investigators at the Icahn School of Medicine at Mount Sinai have designed an innovative RNA-based strategy to activate dendritic cells-;which play a key role in immune response-;that eradicated tumors and prevented their recurrence in mouse models of melanoma.

28 Jul 2023

Bioengineers Harness 3D Printing to Create Functional Heart Ventricle

Over the last decade, advances in 3D printing have unlocked new possibilities for bioengineers to build heart tissues and structures.

28 Jul 2023

New Proof-of-Concept Model for Delivering Gene Editing Tools to Treat Blood Disorders

In a step forward in the development of genetic medicines, researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have developed a proof-of-concept model for delivering gene editing tools to treat blood disorders, allowing for the modification of diseased blood cells directly within the body.

28 Jul 2023

New Collaboration Aims to Advance Cancer Therapies Against Previously Undruggable Targets

The University of Texas MD Anderson Cancer Center and Nexo Therapeutics today announced a multi-year strategic collaboration that aligns the innovative technology and capabilities of each organization at the earliest stages of drug discovery and development to rapidly advance impactful new cancer therapies against previously undruggable targets.

26 Jul 2023

T Cells Play a Dual Role in Wasting During Infection

Even though infections can be presented with several different symptoms, one common symptom is known to be the loss of fat and muscle, a process known as wasting.

25 Jul 2023

Bioprocessing Breakthrough: Xheme Non-Toxic, Multifunctional Additive Eliminates Oxidative Stress

Oxidative stress, caused by an imbalance of free radicals and antioxidants, regularly reduces the yield of pharmaceuticals and therapeutics produced via bioprocessing by about 10-15%. Now, Xheme, Inc.'s Xheme Multifunctional Additive (XMA), a programmable non-toxic nanoporous microparticle, has demonstrated the ability to significantly reduce or eliminate the damage of oxidative stress in bioprocessing conditions.

25 Jul 2023

therapeutics News and Research

Crick Researchers Identify Stem Cells in Thymus for First Time

New Insights into MCM8/9 Enzyme Could Lead to Treatments for Infertility and Cancer

Intellegens and CPI Awarded £1.6 m Innovate UK Grant to Advance Manufacture of Oligonucleotide Therapeutics with Machine Learning

Scientists Uncover New Mechanism for Degrading Short-Lived Proteins

Waters Corporation and Princeton University Announce Multi-Year Research Collaboration

Bioengineered Enzyme-Based Scissors can Selectively Remove Mucins Off Cancer Cells

Single Injection of CRISPR Gene-Editing Treatment Safely Removes SIV From Non-Human Primates

Newly Developed Antibody Therapy to Have Benefits Over Existing Opioid-Overdose Treatments

Gene Therapy Prevents Progression of Kidney Disease in Children

Researchers Elucidate STING Protein's New Role in Immune Defense

Study Shows How Sensory Neurons Control Gastrointestinal Tracts

The Peptoid Approach to Antiviral Resistance

New Breakthrough in Generative AI Models and AlphaFold Structures for Drug Discovery

Alligator Bioscience Announce Milestone Achievement in 2021 Immuno-Oncology Research Collaboration and License Agreement with Orion Corporation

RNA-Based CATCH Strategy Aims to Activate Dendritic Cells

Bioengineers Harness 3D Printing to Create Functional Heart Ventricle

New Proof-of-Concept Model for Delivering Gene Editing Tools to Treat Blood Disorders

New Collaboration Aims to Advance Cancer Therapies Against Previously Undruggable Targets

T Cells Play a Dual Role in Wasting During Infection

Bioprocessing Breakthrough: Xheme Non-Toxic, Multifunctional Additive Eliminates Oxidative Stress

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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