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Study provides a feasible tool to evaluate vesicular endocytosis of NPC1L1-cargos and cholesterol absorption

Excessive cholesterol absorption from intestinal lumen contributes to the pathogenesis of hypercholesterolemia, which is a well-established risk factor for atherosclerotic cardiovascular disease.

29 Mar 2023

3D cell culture system may be a valuable tool for assessing drug efficacy on tumor growth

Fibroblasts build and maintain the extracellular matrix, or physical scaffolding for cells, in the connective tissues within the body.

29 Mar 2023

The proper implementation of stem cell-based disease models

Scientists have learned how to manufacture induced pluripotent stem cells (iPSC) from regular cells through genetic reprogramming during the last ten years.

29 Mar 2023

Determining the structure of protein pumps using cryo-EM

A rare, genetic disorder known as Hailey-Hailey disease causes patches of blisters to develop mainly in the folds of skin under the breasts, in the groin, and the armpits.

29 Mar 2023

Researchers develop a novel probe for selectively dyeing M1 and M2 macrophages

M1 and M2 are activated macrophages that protect our immune system and maintain homeostasis.

28 Mar 2023

Myeloid cells contribute to a long-lived HIV reservoir, study shows

A subset of white blood cells, known as myeloid cells, can harbor HIV in people who have been virally suppressed for years on antiretroviral therapy, according to findings from a small study supported by the National Institutes of Health.

28 Mar 2023

Human cells shed light on basic squid biology

Squids and octopuses are masters of camouflage, blending into their environment to evade predators or surprise prey.

28 Mar 2023

Finding how the global regulation factor reshapes the cell-fate-decision landscape

Determining cell differentiation trajectories has been done by genes and the regulation relationships among them creating complicated networks.

28 Mar 2023

Newest variant of mScarlet3 to help track protein movements in living cells

Biologists frequently utilize a method to figure out why a cell divides, secretes hormones, or sends a signal to another cell. They attach colored lights to the proteins of interest so that they can see their motions and interactions in living cells under a microscope.

28 Mar 2023

Investigating methanogens to unravel the genetics of temperature adaptation

The history of the Earth has been one of physical extremes-;extreme atmospheric conditions, extreme chemical environments, and extreme temperatures.

28 Mar 2023

Monocytes harbor stable HIV DNA capable of infecting neighboring cells

To develop treatments that may one day entirely rid the body of HIV infection, scientists have long sought to identify all of the places that the virus can hide its genetic code.

28 Mar 2023

Scientists develop a detailed "protein atlas" of a pathogen for the first time

A parasite which has devasting impacts on agriculture and human health is the first pathogen to have its proteins located and mapped within its cells – providing clues to their function and helping to identify potential drug targets.

27 Mar 2023

Thickness of cancer cells' glycocalyx barrier determines immune cell evasion of tumors

One of the ways that cancer cells hide from the body's immune system is by forming a thin surface barrier called the glycocalyx.

27 Mar 2023

Potential therapeutic target in KRAS-mutant pancreatic cancer identified

A new research paper was published in Genes & Cancer on March 10, 2023, entitled, "VCP/p97, a pleiotropic protein regulator of the DNA damage response and proteostasis, is a potential therapeutic target in KRAS-mutant pancreatic cancer."

27 Mar 2023

Meta-scale approach to quantifying the protein variants in the human body

A key conundrum in biology is why many very simple creatures, such as the widely studied worm C. elegans, have almost as many genes as the human genome, which has about 20,000 genes.

27 Mar 2023

Immune system’s aptitude in reducing reliance on antibiotics for treating infections

The removal of obsolete and damaged cell components by the body is crucial for fighting diseases like tuberculosis (TB), which establish themselves inside human cells, according to researchers from the Francis Crick Institute.

27 Mar 2023

Analyzing how the global regulation factor reshapes the cell-fate-decision landscape

Genes and their regulatory relationships form complex networks that govern cell differentiation trajectories. However, predicting and understanding cell fate decisions using bottom-up network topology is still side-lined.

27 Mar 2023

Understanding the cellular effects of antibiotics targeting cell wall biosynthesis

It is still unclear how antibiotics work to destroy bacteria. This knowledge, however, is required for the development of new antibiotics. That is exactly what is required because bacteria are becoming increasingly resistant to existing antibiotics.

27 Mar 2023

Key gene involved in crop alkaline tolerance discovered

Chinese scientists have identified a key gene involved in crop alkaline tolerance that may greatly improve crop yield in sodic environments through the use of genetic engineering.

24 Mar 2023

New breakthrough in controlling plant responses to temperature

UC Riverside scientists have significantly advanced the race to control plant responses to temperature on a rapidly warming planet.

24 Mar 2023

Cell News and Research

Study provides a feasible tool to evaluate vesicular endocytosis of NPC1L1-cargos and cholesterol absorption

3D cell culture system may be a valuable tool for assessing drug efficacy on tumor growth

The proper implementation of stem cell-based disease models

Determining the structure of protein pumps using cryo-EM

Researchers develop a novel probe for selectively dyeing M1 and M2 macrophages

Myeloid cells contribute to a long-lived HIV reservoir, study shows

Human cells shed light on basic squid biology

Finding how the global regulation factor reshapes the cell-fate-decision landscape

Newest variant of mScarlet3 to help track protein movements in living cells

Investigating methanogens to unravel the genetics of temperature adaptation

Monocytes harbor stable HIV DNA capable of infecting neighboring cells

Scientists develop a detailed "protein atlas" of a pathogen for the first time

Thickness of cancer cells' glycocalyx barrier determines immune cell evasion of tumors

Potential therapeutic target in KRAS-mutant pancreatic cancer identified

Meta-scale approach to quantifying the protein variants in the human body

Immune system’s aptitude in reducing reliance on antibiotics for treating infections

Analyzing how the global regulation factor reshapes the cell-fate-decision landscape

Understanding the cellular effects of antibiotics targeting cell wall biosynthesis

Key gene involved in crop alkaline tolerance discovered

New breakthrough in controlling plant responses to temperature

Driving Support for Pharmaceutical Testing Through Continuous Innovation

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Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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