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Scientists use computational biology to identify functional elements in the human genome

UMass Medical School researchers Zhiping Weng, PhD, and Jill Moore, PhD, and MD/PhD students Michael Purcaro and Henry Pratt are lead authors on the latest publication of data from the ambitious ENCODE project.

30 Jul 2020

Olympus and Cytosurge collaborate to deliver a complete single-cell and CRISPR genetic manipulation solution in the Americas

Olympus, a leading manufacturer of high-end research microscopes, and Cytosurge, a precision manufacturer of cell manipulation technologies, have entered a co-marketing agreement to become a complete system provider to the scientific community’s growing need for next-generation single-cell and CRISPR genetic manipulation solutions.

From Cytosurge AG 29 Jul 2020

Multiomics analysis reveals multiple characteristics of HIV-1-producing cells in vivo

For eradication of HIV-1 infection, it is important to elucidate the detailed features and heterogeneity of HIV-1-infected cells in vivo.

29 Jul 2020

Scientists map the genome of aphid-like pest that decimates vineyards

Following a decade-long effort, scientists have mapped out the genome of an aphid-like pest capable of decimating vineyards. In so doing, they have discovered how it spreads -- and potentially how to stop it.

29 Jul 2020

Deep learning algorithm can infer molecular alterations in cancer from histology images

Researchers at the University of Chicago Medicine Comprehensive Cancer Center, working with colleagues in Europe, created a deep learning algorithm that can infer molecular alterations directly from routine histology images across multiple common tumor types.

29 Jul 2020

Scientists discover evolutionary lineage of SARS-CoV-2 virus

By reconstructing the evolutionary history of SARS-CoV-2, the virus that is responsible for the COVID-19 pandemic, an international research team of Chinese, European and U.S. scientists has discovered that the lineage that gave rise to the virus has been circulating in bats for decades and likely includes other viruses with the ability to infect humans.

29 Jul 2020

Human genome may explain the neonatal origins of immune and inflammatory diseases

A study published in the journal Nature Communications has pinpointed a number of areas of the human genome that may help explain the neonatal origins of chronic immune and inflammatory diseases of later life, including type 1 diabetes, rheumatoid arthritis and coeliac disease.

29 Jul 2020

Study sheds new light on core regulatory networks that govern cell types in vertebrates

The FANTOM Consortium has shed new light into the main regulatory networks that govern the types of cells found in different vertebrate species.

29 Jul 2020

New technology helps visualize entire genome at molecular resolution

Scientists from Harvard University, CNAG, and CRG have demonstrated a pioneering technology that helps observe hundreds of genomes under the microscope.

29 Jul 2020

AI algorithm can identify patterns of mutations and prognosis from tumor images

Researchers at EMBL's European Bioinformatics Institute, the Wellcome Sanger Institute, Addenbrooke's Hospital in Cambridge, UK, and collaborators have developed an artificial intelligence algorithm that uses computer vision to analyse tissue samples from cancer patients.

28 Jul 2020

A novel approach to identify cancer targets using 'synthetic lethality'

With advances in genome sequencing, cancer treatments have increasingly sought to leverage the idea of "synthetic lethality," exploiting cancer-specific genetic defects to identify targets that are uniquely essential to the survival of cancer cells.

28 Jul 2020

EBV viral genome modifies the host epigenetic landscape to promote gastric cancer

The Epstein-Barr virus (EBV), one of the most common human viruses, is associated with about 8-10 per cent of stomach -- or gastric -- cancers, the third leading cause of cancer death globally.

28 Jul 2020

Artificial intelligence-based process can help design novel proteins

Proteins are known to perform complex tasks and catalyze chemical reactions, making them crucial for cell survival.

27 Jul 2020

Rare gene mutation eliminates immune cell population

A study has allowed researchers to identify a rare human gene mutation that removes a population of immune cells, called mucosal-associated invariant T cells.

27 Jul 2020

Genome editing technologies can help understand disease-associated genetic mutations

Scientists have developed novel genome-editing technology that could help understand disease-related genetic mutations based on C-to-G single base variations.

27 Jul 2020

Epigenomic data can help characterize genes that play key role in cancer progression

As cancer cells evolve, many of their genes become overactive while others are turned down. These genetic changes can help tumors grow out of control and become more aggressive, adapt to changing conditions, and eventually lead the tumor to metastasize and spread elsewhere in the body.

From Massachusetts Institute of Technology (MIT) 24 Jul 2020

New startup launched to overcome the challenge of delivering next-generation therapeutics

Harvard University's Office of Technology Development (OTD) and the Harvard T.H. Chan School of Public Health today announced the launch of Vesigen Therapeutics, a startup company that aims to overcome the challenge of delivering next-generation therapeutics, such as gene-editing complexes, RNA molecules, and other large proteins, to intracellular targets in specific tissues of interest.

23 Jul 2020

Genome News and Research

Scientists use computational biology to identify functional elements in the human genome

Olympus and Cytosurge collaborate to deliver a complete single-cell and CRISPR genetic manipulation solution in the Americas

Multiomics analysis reveals multiple characteristics of HIV-1-producing cells in vivo

Scientists map the genome of aphid-like pest that decimates vineyards

Deep learning algorithm can infer molecular alterations in cancer from histology images

Scientists discover evolutionary lineage of SARS-CoV-2 virus

Human genome may explain the neonatal origins of immune and inflammatory diseases

Study sheds new light on core regulatory networks that govern cell types in vertebrates

New technology helps visualize entire genome at molecular resolution

AI algorithm can identify patterns of mutations and prognosis from tumor images

A novel approach to identify cancer targets using 'synthetic lethality'

EBV viral genome modifies the host epigenetic landscape to promote gastric cancer

Artificial intelligence-based process can help design novel proteins

Rare gene mutation eliminates immune cell population

Genome editing technologies can help understand disease-associated genetic mutations

Epigenomic data can help characterize genes that play key role in cancer progression

New startup launched to overcome the challenge of delivering next-generation therapeutics

New pathways that could help treat RNA viruses discovered

Simple DNA repeats can be the basis for genetic computers

Novel genetic measure could improve screening for osteoporosis

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