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Engineering Tissue Domains with a Synthetic Biology Approach

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, demonstrate how morphogens combined with cell adhesion can generate tissue domains with a sharp boundary in an in vitro model system.

9 Oct 2024

Scientists Develop Lab-Grown Muscle Stem Cells for Advanced Regenerative Therapies

Recent findings reveal that induced satellite cells can effectively regenerate muscle tissue, outperforming traditional myoblasts in engraftment and function.

23 Sep 2024

Study Utilizes Flow Cytometry and Advanced Transcriptomics to Reveal Age-Related Defects in Thymic Regeneration

Research identifies two states of age-associated thymic epithelial cells, linking thymic degeneration to aging and injury, impacting immune system function.

26 Aug 2024

Harnessing Immune Cell Triads for Effective Cancer Treatment

There's a frustrating fact about today's immunotherapies for cancer. While sometimes they work beautifully -; completely eliminating or greatly reducing cancer in particular patients -; other times they don't work at all. It's a mystery.

16 Jul 2024

Inverse relationship found between anti-inflammatory macrophages and NK cells/T cells in lung cancer

Single-cell ribonucleic acid sequencing (scRNAseq) and spatial transcriptomics to study cellular organization and interactions within the tumor microenvironment.

30 May 2024

SMART Researchers Pioneer Novel Microfluidic Method to Optimize Bone Marrow Stem Cell Extraction for Advanced Cell Therapies

Researchers from the Critical Analytics for Manufacturing Personalized-Medicine (CAMP) Interdisciplinary Research Group (IRG) of Singapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, in collaboration with the Agency for Science, Technology and Research (A*STAR) Bioprocessing Technology Institute (BTI) and National University Health System (NUHS), have developed a groundbreaking technology.

22 Nov 2023

Study Finds Insights to Improve Understanding of Microbes’ Function

In a recent study, a team of researchers led by Penn State discovered hints that could assist in better understanding the role microbes play in creating a living skin over many semi-arid ecosystems around the world.

14 Aug 2023

New Method for Cell Type-Specific Mapping of Ion Distribution in Plants

Plant roots play a critical role in taking up, selecting, enriching and retaining a range of different mineral elements thereby supplying distant plant tissues with nutrients while sequestering excessive amounts of metals.

13 Jun 2023

Neuronal Activity Necessary and Sufficient to Drive Astrocyte Development

Researchers at Baylor College of Medicine have unraveled the processes that give astrocytes, the most abundant glial cell in the brain, their special bushy shape, which is fundamental for brain function.

27 Apr 2023

CloneTracer Reveals a Differentiation Landscape of Acute Myeloid Leukemia

Researchers have developed a new method to distinguish between cancerous and healthy stem cells and progenitor cells from samples of patients with acute myeloid leukemia (AML), a disease driven by malignant blood stem cells that have historically been difficult to identify.

25 Apr 2023

New Epigenetic Vulnerability Of Acute Myeloid Leukemia Revealed

Acute myeloid leukemia (AML) is an aggressive blood cancer that causes uncontrolled accumulation of white blood cells. Because of the poor outcomes of this disease, researchers across the globe have been on the hunt for new ways to treat AML, while preserving normal blood development.

10 Apr 2023

First Steps Driving Antibiotic Resistance Discovered

Antibiotic resistance is a global health threat. In 2019 alone, an estimated 1.3 million deaths were attributed to antibiotic resistant bacterial infections worldwide.

3 Apr 2023

Using ultrasound waves to move genetically engineered cells

Let's say you needed to move an individual cell from one place to another. How would you do it? Maybe some special tweezers? A really tiny shovel?

24 Feb 2023

Bacteria do engage in photosynthesis, research suggests

Knowing whether or not marine microbes engage in photosynthesis -; the use of sunlight to turn carbon dioxide and water into energy -; could help scientists to learn if ocean bacteria play a role in the global carbon cycle.

25 Oct 2022

Single-cell functional tool screens active ARB in native soils

Soil antimicrobial resistance (AMR) poses significant health risks due to the possibility of transfer to humans via direct contact and the food chain.

3 Oct 2022

Study provides insight into how birds decide their sex

A study team has examined chicken germ cells using RNA-sequencing to anticipate the mechanism that determines the sex to better understand the process of the sex determination in the germ cell.

12 Sep 2022

16 distinct cell populations identified in a key brain region for substance use disorders

In a work of systematic biology that advances the field, University of Alabama at Birmingham researchers have identified 16 distinct cell populations in a complex area of the midbrain called the ventral tegmental area, or VTA.

18 Apr 2022

Study highlights how IL-2 regulates developmental bifurcation

The immune system is a complicated network of cells and proteins that performs a straightforward function—protecting the body against infection.

15 Feb 2022

Novel technology combats cancer more quickly and efficiently

Researchers have created a new technology that allows them to use immune cells from tumors to combat cancer more quickly and efficiently.

31 Jan 2022

High-speed cell sorter rapidly isolates and quantifies cells with complex cellular phenotypes

Isolating individual cells with complex phenotypes – which is key to understanding how these cells function, including to inform disease – is a technological challenge. Now, overcoming this hurdle, researchers present a high-speed cell sorter that uses fluorescence imaging to enable genome-scale studies of complex phenotypes.

21 Jan 2022