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A Novel Method for Incorporating Non-Canonical Amino Acids into Proteins

Every basic biology lesson teaches that proteins are made up of combinations of 20 distinct amino acids, which are ordered in various patterns similar to words.

12 Sep 2024

The Influence of 'Silent' Mutations on Genetic Disorders

Genetic disorders -; like cystic fibrosis and Huntington's disease -; are considered incurable, with gene mutations occurring in essentially every cell of the body.

29 Aug 2024

Decoding Dengue: The Use of Less Efficient Codons for Viral Advantage

Mosquito-borne viral infections once confined to tropical regions are spreading. Dengue virus infects up to 400 million people worldwide each year according to World Health Organization estimates, and no available treatments exist for this disease.

24 Jul 2024

Outsmarting Viruses: Scientists Rewire Bacteria for Biomanufacturing Revolution

Genome engineering allows scientists to modify the genetic code of microbes. Now, researchers have engineered the genome of the bacterium Escherichia coli (E. coli) to make it immune to viral infections.

6 Feb 2024

The Distinct Divergence in the Genetic Code

A protist’s genome revealed an apparently unusual divergence in the DNA coding signaling the end of a gene, indicating the need for more research to better comprehend this varied group of creatures.

6 Oct 2023

New Collaboration Aims to Advance Cancer Therapies Against Previously Undruggable Targets

The University of Texas MD Anderson Cancer Center and Nexo Therapeutics today announced a multi-year strategic collaboration that aligns the innovative technology and capabilities of each organization at the earliest stages of drug discovery and development to rapidly advance impactful new cancer therapies against previously undruggable targets.

26 Jul 2023

Using a programmable control switch to deliver therapeutic RNA molecules to target cells

Using an RNA sensor, MIT engineers have designed a new way to trigger cells to turn on a synthetic gene.

17 Mar 2023

Novel web-based tool deoptimizes genetic sequences based on different codon usage

A new software tool developed by Texas Biomedical Research Institute and collaborators can help scientists and vaccine developers quickly edit genetic blueprints of pathogens to make them less harmful.

16 Mar 2023

Learning about cellular proteins through “snapshots” of translation

Pep-tRNAs, nascent polypeptides inside the ribosome that are covalently connected to transfer RNA, are engaged in a variety of cell processes, including gene expression, according to advances in molecular biology.

1 Feb 2023

Chilling tolerance trait in rice with the codon repeats at a single site

A recent study performed by Professor Chong Kang’s group from the Institute of Botany of the Chinese Academy of Sciences (CAS) has disclosed a fact that a novel cold domesticated repair mechanism for DNA damage in rice.

11 Jan 2023

Spirea raises £2.4M ($3M) to develop antibody drug conjugates in cancer

Funding will enable the development of Spirea’s pipeline of antibody drug conjugate therapeutics for the treatment of solid tumours.

From Spirea 14 Jun 2022

Researchers analyze the potential role of mRNA in drug development and novel therapies

In latest years, messenger RNA—the DNA’s close relative in the complex process of turning a string of genetic blueprints into a properly functioning organism—has gotten a lot of attention in the scientific and medical community.

29 Apr 2022

Researchers explore how tRNAs evolve in protein synthesis

In the process of protein synthesis, a peptide bond is formed between two amino acids that are bound to two different transfer RNAs (tRNAs). Researchers have long been perplexed as to how these tRNAs evolved to be so near to one another on the ribosome.

From Tokyo University of Science 22 Apr 2022

Semarion raises £2.14 million GBP ($2.89 million USD) seed funding

Semarion Ltd, a University of Cambridge spin-out company from the Cavendish Laboratory combining materials engineering and cell biology to tackle unmet drug screening needs, announced today that it has closed a £2.14 million GBP seed funding round.

22 Feb 2022

Ingenza collaborates with Johnson Matthey for efficient industrial enzyme synthesis

Biotechnology company Ingenza is excited to report the successful conclusion to its recent six-month project with Johnson Matthey.

1 Feb 2022

Researchers develop key components of an expanded genetic code system

Modern biologists nurture more ambitious goals and one among them is to know how to broaden or alternatively modify the genetic code of life on Earth.

1 Oct 2021

Study opens new avenues for therapies against Charcot-Marie-Tooth disease

CMT, a rare hereditary condition, commences when genetic changes interrupt the transmission of nerve signals from the brain to the muscles of the extremities, specifically those of the lower limbs.

16 Sep 2021

Researchers reveal why nerve cell’s protein production slows down in CMT patients

A team led by MDC researcher Marina Chekulaeva has figured out why protein production slows down in the nerve cells of people suffering from Charcot-Marie-Tooth disease. This discovery could lead to a new therapeutic approach, the scientists report in the journal "Nucleic Acids Research".

16 Sep 2021

Scientists identify the language the body uses to marshal responses to threats

UCLA life scientists have identified six "words" that specific immune cells use to call up immune defense genes -- an important step toward understanding the language the body uses to marshal responses to threats.

13 May 2021

National DNA Day 2021: An Interview with Professor George Church

In celebration of National DNA Day, AZoLifeSciences interviews renowned DNA expert Professor George Church about his life-long career in DNA research.

From Harvard Medical School 23 Apr 2021