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Tumor Recurrence Prediction from Multi-Omics Information by Deep Learning

MULGONET combines deep learning and multi-omics analysis to predict tumor recurrence, addressing interpretability and enhancing cancer prognosis understanding.

16 Apr 2025

Scientists Unveil Dynamic Structure of Vision-Linked Protein RBP3

Scientists have for the first time looked deep into the protein structure that may determine our vision - and discovered that it is much more dynamic than previously thought.

8 Apr 2025

Carbon Dot-Based Fluorosensor Shows Superior Performance in Enterovirus RNA Detection

Scientists from the University of Jyväskylä's Nanoscience Center in Finland have introduced a novel, label-free ratiometric fluorosensor intended for the sensitive and specific detection of enteroviral RNA.

7 Apr 2025

Scientists Design Ultra-Stable Synthetic Proteins That Could Change Drug Discovery

Innovative designs of GPCRs with enhanced signaling and stability offer new insights for drug discovery and synthetic biology, transforming protein engineering.

3 Feb 2025

New Method for Engineering GPCRs Opens Pathways for Advanced Drug Development

Proteins are life's engines, powering processes like muscle movement, vision, and chemical reactions.

24 Jan 2025

New computational strategy enables design of drug-induced protein interactions

A novel geometric deep learning framework designs ligand-specific protein binders, enhancing therapeutic potential in cell therapies and synthetic biology.

22 Jan 2025

Uncovering Key Differences Between Humans and Mice in Cancer Immunotherapy Targets

“Programmed cell death protein 1,” or PD-1, has been considered a key target in cancer therapies since its discovery in the 1990s.

6 Jan 2025

Comprehensive Review of Intracellular Checkpoints in NK Cell Biology and Cancer

Natural killer (NK) cells play an important role in the innate immune response to cancer and viral infections, and their presence in tumors correlates with improved patient outcomes in a variety of cancers.

29 Nov 2024

New Insights into the Mechanism of Glycan Branch Formation

Glycans are sugar chains that bind to cells via proteins or lipids, altering their chemical properties

30 Oct 2024

A Novel Method for Improving Spatial Resolution in Transcriptomic Analysis

Existing spatial transcriptomics methods frequently lack the precision required to examine single cells in tissue samples, hindering their ability to reveal intricate biological information.

21 Oct 2024

Engineering Tissue Domains with a Synthetic Biology Approach

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, demonstrate how morphogens combined with cell adhesion can generate tissue domains with a sharp boundary in an in vitro model system.

9 Oct 2024

Comprehensive multi-omics approach reveals detailed insights into diabetes mechanisms

In a recent study published in Nature Communications, researchers utilized a comprehensive multi-omics approach, integrating genomic, proteomic, and metabolomic data from a diverse cohort, to uncover detailed molecular interactions and identify distinct diabetes subgroups.

20 Sep 2024

European Commission Approves Erdafitinib for Advanced Urothelial Carcinoma

Janssen-Cilag International NV, a Johnson & Johnson company, today announced that the European Commission (EC) has approved BALVERSA®▼(erdafitinib) as a once-daily oral monotherapy for the treatment of adult patients with unresectable or metastatic urothelial carcinoma (mUC), harbouring susceptible fibroblast growth factor receptor 3 (FGFR3) genetic alterations who have previously received at least one line of therapy containing a programmed death receptor-1 (PD-1) or programmed death-ligand 1 (PD-L1) inhibitor in the unresectable or metastatic treatment setting.

30 Aug 2024

Ligand News and Research

Tumor Recurrence Prediction from Multi-Omics Information by Deep Learning

Scientists Unveil Dynamic Structure of Vision-Linked Protein RBP3

Carbon Dot-Based Fluorosensor Shows Superior Performance in Enterovirus RNA Detection

Scientists Design Ultra-Stable Synthetic Proteins That Could Change Drug Discovery

New Method for Engineering GPCRs Opens Pathways for Advanced Drug Development

New computational strategy enables design of drug-induced protein interactions

Uncovering Key Differences Between Humans and Mice in Cancer Immunotherapy Targets

Comprehensive Review of Intracellular Checkpoints in NK Cell Biology and Cancer

New Insights into the Mechanism of Glycan Branch Formation

A Novel Method for Improving Spatial Resolution in Transcriptomic Analysis

Engineering Tissue Domains with a Synthetic Biology Approach

Comprehensive multi-omics approach reveals detailed insights into diabetes mechanisms

European Commission Approves Erdafitinib for Advanced Urothelial Carcinoma

Novel Drug Targets in Gardnerella Vaginalis: A Bioinformatics Approach to Combat Bacterial Vaginosis

Surface Plasmon Resonance Sensors: Transforming Drug Development and Clinical Diagnostics

Artificial Intelligence Drives Breakthroughs in Drug Discovery, Reducing Costs and Timelines

Australian Researchers Introduce Groundbreaking AI Tool for Early Stage Drug Discovery

Integrative genomic study identifies two new potential drug targets in Mycobacterium tuberculosis

Remote ischemic conditioning:A potential treatment option for necrotizing enterocolitis

Cooperative Synthesis of Vitamin B12 by Marine Bacterial Partners

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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