Nanoparticle News and Research

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In nanotechnology, a particle is defined as a small object that behaves as a whole unit in terms of its transport and properties. It is further classified according to size: in terms of diameter, fine particles cover a range between 100 and 2500 nanometers, while ultrafine particles, on the other hand, are sized between 1 and 100 nanometers.

4basebio Receives MHRA GMP Licence for Manufacture and Supply of Synthetic DNA

4basebio PLC (“4basebio”), a company which develops and commercializes the large-scale manufacture of synthetic DNA as well as nanoparticle delivery solutions, today announced that it has received Good Manufacturing Practice (GMP) certification from the UK’s Medicines and Healthcare products Regulatory Agency (MHRA).

3 Apr 2025

Unlocking the Role of lncRNAs in MASLD and Liver Fibrosis

Metabolic dysfunction-associated steatotic liver disease (MASLD), previously termed non-alcoholic fatty liver disease (NAFLD), represents a widespread health concern, impacting approximately 30% of the global adult population.

3 Mar 2025

New Lipid Nanoparticles Deliver mRNA for Lung Tissue Regeneration

New research from the Perelman School of Medicine at the University of Pennsylvania suggests that a combination of messenger RNA (mRNA) and a novel lipid nanoparticle (LNP) could potentially be used to repair lung damage.

24 Feb 2025

New Breakthrough Pushes DNA-Nanoparticle Motors Closer to Natural Protein Speed

DNA-nanoparticle motors are exactly as they sound: tiny artificial motors that use the structures of DNA and RNA to propel motion by enzymatic RNA degradation.

23 Jan 2025

Targeting Cancer with Nanoparticle-Delivered Gene Therapy

Scientists are literally shining a laser on the energy centers of cancer cells in an attempt to harm these sources of power and cause widespread cancer cell death.

16 Dec 2024

New Era of Combined mRNA and RNAi Therapies

Researchers at the University of Ottawa have figured out how to use mRNA and RNAI-based treatments to treat complex illnesses like cancer and heart disease.

10 Dec 2024

Novel Approach to Lipid Nanoparticle Engineering

To enhance mRNA distribution, Penn engineers have created an ideal “recipe” for ionizable lipids, which are essential components of lipid nanoparticles (LNPs), the molecules that underlie the COVID-19 vaccines and other cutting-edge treatments.

25 Nov 2024

Stem-Like CD4 T Cells Could Transform Cancer Treatment Strategies

Researchers at Winship Cancer Institute of Emory University have identified a novel type of immune cell, called the stem-like CD4 T cell, that plays a pivotal role in anti-tumor immunity.

28 Oct 2024

New Approach Aims to Enhance CRISPR Safety and Precision

CRISPR is a revolutionary tool that allows scientists to precisely modify the genome and gene expression of cells in any organism.

8 Oct 2024

Modified Nucleotides Boost saRNA Vaccine Efficacy and Protection Against SARS-CoV-2

Modified nucleotides like m5C in saRNA enhance vaccine efficacy, stability, and reduce inflammation, offering a promising approach for SARS-CoV-2 protection.

18 Sep 2024

Breakthrough Nanoparticle Therapy Boosts Immune Response Against Aggressive Pancreatic Cancer

Innovative use of lipid nanoparticles to deliver immune agonists shows promise in activating anti-tumor immunity in pancreatic ductal adenocarcinoma models.

9 Sep 2024

Lipid Nanoparticle-Encapsulated miR-193a-3p Mimic INT-1B3 Boosts Anti-Tumor Immunity

A new research paper was published in Oncotarget's Volume 15 on July 12, 2024, entitled, "INT-1B3, an LNP formulated miR-193a-3p mimic, promotes anti-tumor immunity by enhancing T cell mediated immune responses via modulation of the tumor microenvironment and induction of immunogenic cell death."

6 Aug 2024

Exploring Drug Repurposing For Arboviral Infections Through Cavitomix

The CavitOmiX drug discovery method, developed by the drug and enzyme discovery platform Innophore.

2 Aug 2024

All-RNA Gene Writing Method Paves Way for Precise Gene Editing in Human Cells

A novel gene-writing technology based on retrotransposons.

15 Jul 2024

Virus-Like Nanoparticles Facilitate DNA Release and Host Reproduction in Streptomyces

Viruses are ubiquitous in the environment, and organisms have developed various mechanisms to counter their threat.

12 Jun 2024

Novel Protein 'Cloaking' Technique for Enhanced Therapeutic Applications

Cornell University scientists have designed a way to "cloak" proteins in a generalized technique that could lead to repurposing things like antibodies for biological research and therapeutic applications.

29 May 2024

Deep Proteomic Analysis Unveils Molecular Changes in Skeletal Muscle with Aging and Resistance Training

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 8, entitled, "A novel deep proteomic approach in human skeletal muscle unveils distinct molecular signatures affected by aging and resistance training."

2 May 2024

Using Nanoparticles to Inactivate Multidrug-Resistant Bacteria

An article published in the Journal of Environmental Chemical Engineering describes a possible strategy for promoting selective inhibition of multidrug-resistant bacteria, which are increasingly abundant owing to the indiscriminate use of antibiotics and are therefore a major human health hazard.

4 Apr 2024

Acidic Fortress of Tumors Could Rebuff Immune Cells

Cancer cells release a significantly more concentrated level of acid than previously known, forming an "acid wall" that could deter immune cells from attacking tumors, UT Southwestern Medical Center scientists show in a new study.

2 Apr 2024

Scientists Pioneer mRNA Approach to Target Alzheimer's Protein

Scientists at The Florey have developed an mRNA technology approach to target the toxic protein tau, which builds up in patients with Alzheimer's disease and other dementias.

29 Mar 2024