Pulmonary Fibrosis News and Research

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Genes2Genes Unlocks New Potential for Detecting Gene Expression Changes

Genes2Genes an accurately infer alignments in simulated and real datasets of single-cell trajectories and capture sequential mismatches and matches in individual genes.

4 Oct 2024

Study Reveals Immune Cells' Role in Lung Scarring After Viral Infections

Investigators involved in a multicenter study co-led by Cedars-Sinai discovered a pathway by which immune cells prevent the lungs' protective barrier from healing after viral infections like COVID-19.

5 Sep 2024

Study Shows the Ability of Protein 'Signatures' to Predict Onset of 67 Diseases

Research on thousands of proteins measured from a drop of blood demonstrates the ability of proteins to predict the onset of many diverse diseases.

24 Jul 2024

Study Highlights MSC-EVs Potential for Alleviating Lung Fibrosis

Pulmonary fibrosis (PF) is a chronic interstitial lung disease characterized by fibroblast proliferation and extracellular matrix formation, causing structural damage and lung failure.

27 Jun 2024

Different Chromosomes Found to Have Separate End-Specific Telomere-Length Distributions

We depend on our cells being able to divide and multiply, whether it's to replace sunburnt skin or replenish our blood supply and recover from injury.

12 Apr 2024

Free AI Drug Discovery Course Surpasses 2,500 Users

An online course on Disease Modeling and Target Discovery launched 7 months ago by clinical stage generative artificial intelligence (AI)-driven biotechnology company Insilico Medicine has surpassed 2,500 users.

12 Dec 2023

New Breakthrough in Generative AI Models and AlphaFold Structures for Drug Discovery

Insilico Medicine ("Insilico"), a clinical-stage end-to-end generative artificial intelligence (AI) drug discovery company, has achieved a significant breakthrough in the application of multiple generative AI models and AlphaFold structures for drug discovery.

3 Aug 2023

iPSC-Based Model System Helps Study Lung-Specific Mesenchyme

Lung mesenchymal cells, which are crucial components of the lung’s distinctive structure, also play a significant role in disease and injury recovery, but research into their biology and how they start disorders like pulmonary fibrosis is limited.

14 Jun 2023

The Implications of Biological Clock on Lung Health

The body’s biological clock is interfered with by abnormal sleep habits, such as those of night shift workers, which have been connected to lung health problems.

18 Apr 2023

New nanoparticles can deliver mRNA encoding CRISPR/Cas9 components to the lungs

Engineers at MIT and the University of Massachusetts Medical School have designed a new type of nanoparticle that can be administered to the lungs, where it can deliver messenger RNA encoding useful proteins.

31 Mar 2023

Previously unknown telomere and cancer connection to the immune system revealed

Johns Hopkins Medicine scientists say their 20-year study of more than 200 people with premature aging syndromes caused by abnormally short telomeres, or shortened repetitive DNA sequences at the ends of chromosomes, may upend long-held scientific dogma and settle conflicting studies about how and whether short telomeres contribute to cancer risk.

31 Mar 2023

A protein in the lung forms a natural protective barrier against SARS-CoV-2 infection

University of Sydney scientists have discovered a protein in the lung that blocks SARS-CoV-2 infection and forms a natural protective barrier in the human body.

10 Feb 2023

Study reveals genetic architecture of COVID-19 risk factors and disease complications

According to a recent study of information from the Veterans Affairs Million Veteran Program, there are genetic correlations between COVID-19 severity and specific medical disorders that are established risk factors for severe COVID-19.

3 May 2022

Severe lung injuries can trigger stem cells to undergo abnormal differentiation, study finds

Severe injuries to the lung from diseases such as COVID-19 trigger abnormal stem cell repair that alters the architecture of the lung. The aberrant stem cell differentiation in response to injury can prevent the restoration of normal lung function.

31 Dec 2021

Premature aging of the tracheobronchial stem cells could contribute to chronic lung disease

Are prematurely aged or overworked stem cells a significant factor in chronic lung disease? Findings of a study just released in STEM CELLS Translational Medicine (SCTM) say this is likely so.

22 Sep 2021

Specific subset of fibroblast cells could provide protection from debilitating lung disease

Single-cell RNA sequencing has revealed a subset of cells that could provide protection from a rare, but severely debilitating and fatal, lung disease.

16 Jul 2021

Cells damaged by chronic lung disease favor SARS-CoV-2 entry

Researchers propose that similar to pouring water atop a wellhead prior to pumping, the airway cells of patients suffering from chronic lung diseases are “primed” for infection by the COVID-19 virus.

16 Jul 2021

A new treatment approach against SARS-CoV-2

Scientists have come up with a new method to treat SARS-CoV-2 infection by fixing the cell damage instead of fighting the virus directly.

21 Jun 2021

Researchers construct smallest and cheapest high-resolution microscope

An international team led by researchers of the University of Barcelona builds the smallest and cheapest high-resolution microscope to date.

From University of Barcelona 10 Mar 2021

Microfluidic chip and AI-based microscope help measure hemoglobin levels

Blood count is a test that is often performed to determine the health of patients and generally involves an estimation of the concentration of hemoglobin.

24 Feb 2021