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Discovery of a Subset of Human Short Introns That Are Spliced Out by a Novel Mechanism

The well-known essential pre-mRNA splicing factor U2AF heterodimer (U2AF2–U2AF1) has been considered to mediate early splicing reaction in all introns of different lengths.

15 Feb 2024

TTUHSC Professor Awarded NIH Grant for Potassium Channel Study

Each living cell has small, highly specialized conduits called potassium (K+) channels, which are responsible for the highly selective and fast transfer of K+ ions across cell membranes.

19 May 2023

New family of pharmaceutical compounds that target RNA

In Jennifer Hines’ lab, a group of graduate and undergraduate chemistry students recently discovered a new family of compounds that can target RNA and interfere with its function. In the future, RNA-targeted treatments to treat cancer and metabolic diseases, together with bacterial and viral infections, could be developed using the chemical scaffold found in this research.

15 Feb 2023

Study shows adverse effect of pH-dependent switch in protein interaction

Each biological process depends on pH in one way or another. The human body should maintain constant and specific pH regulation to function efficiently.

27 Oct 2020

Researchers use DSC-based method to measure protein-ligand binding

A team of researchers from Kazan Federal University, Russia, led by Dr. Igor Sedov, reported an application of capillary differential scanning calorimetry technique for the study of the binding of albumin, a plasma transport protein, with different drug ligands.

14 Jul 2020