Cell Biology

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New discovery offers insight into how cells maintain the integrity of DNA

Researchers from Case Western Reserve University have identified a new mechanism by which a protein known for repairing damaged DNA also protects the integrity of DNA by preserving its structural shape.

19 Jan 2022

Immune cells in arteries can sniff out their surroundings and cause inflammation

An artery is not like a nose. Or is it? Scientists at La Jolla Institute for Immunology (LJI) have discovered that immune cells in arteries can "sniff" out their surroundings and cause inflammation.

17 Jan 2022

New finding could lead to the development of cell death regulators for cancer therapies

Scientists led by Professor Ana J. Garcia-Saez at the CECAD Cluster of Excellence for Aging Research at the University of Cologne have shown that apoptosis, the programmed cell death, involves a direct physical interplay between the two proteins BAX and DRP1.

17 Jan 2022

Researchers identify new potential drug target that may block SARS-CoV-2 infection

In the quest for new treatments for COVID-19, a team led by researchers at UC San Francisco has identified a new potential drug target that may block infection by SARS-CoV-2. The protein, called BRD2, regulates the ACE2 receptor, which the novel coronavirus relies on to gain entry to its host's cells.

17 Jan 2022

First molecular images of enzyme may help solve the mystery cause of hereditary neurodegenerative diseases

WEHI researchers have produced the first molecular images of an enzyme that controls proteins to signal and communicate with each other in human cells.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 13 Jan 2022

Research sheds new insights into development of lung macrophages in humans

The lungs are exposed to microorganisms like viruses and bacteria from the moment of the first breath.

13 Jan 2022

Moffitt researchers unravel the role of B cells in endometrial cancer

Endometrial cancer is the most common cancer of the female reproductive system. Patients who have active immune responses against cancer cells tend to have better outcomes, but much of what is known focuses on only one type of immune cell called T cells.

13 Jan 2022

Using E.Coli to bring 3D Printing to Life

In this interview, we speak to Dr. Avinash Manjula Basavanna about his latest research that incorporated E. Coli to bring 3D printing materials to life.

From Massachusetts Institute of Technology (MIT) 13 Jan 2022

Study analyzes the impact of T cells from common cold coronaviruses against SARS-CoV-2 exposure

A new study has illustrated that people having higher levels of T cells from common cold coronaviruses are not likely to get infected with SARS-CoV-2.

13 Jan 2022

Researchers determine how key protein drives the defense system to fight viruses

Scientists have just found a solution to a major mystery that explains how human blood cells train the defense system against viruses. They hope that this discovery will one day allow them to better control the response and either boost or calm it as needed.

13 Jan 2022

Increasing the expression of a gene slows Alzheimer’s progression in mice

According to a recent research, enhancing the expression of one gene in cells that help the brain’s neurons, shields neurons in mouse models of Alzheimer’s disease.

13 Jan 2022

CSHL researchers spotlight the role of a previously little-known protein in leukemia

Acute myeloid leukemia (AML) is an aggressive cancer of white blood cells with few effective targeted therapies available to treat it.

12 Jan 2022

Scientists discover new Senp5S protein with crucial role in brain development

Understanding how the brain develops is crucial to formulating treatments and management protocols for a variety of developmental disorders, as well as degenerative neurological diseases. Right from the embryonic stage, brain development is facilitated by the differentiation of neurons (brain cells).

12 Jan 2022

Targeting MAPK4 in triple-negative breast cancer may lead to improved treatments

Scientific evidence supporting the involvement of the enzyme MAPK4 in cancer growth and resistance to certain therapies has been growing quickly.

12 Jan 2022

New 'disease-in-a-dish' system developed to study oculocutaneous albinism

Researchers at the National Eye Institute have developed the first patient-derived stem cell model for studying eye conditions related to oculocutaneous albinism (OCA).

12 Jan 2022

Researchers reveal molecular and cellular mechanisms that lead to tertiary lymphoid structures formation

Tertiary lymphoid structures are formations that occur outside of the lymphatic system. They contain immune cells and are similar in structure and function to lymph nodes and other lymphoid structures.

12 Jan 2022

Study shows how skin cells act as a firewall against cancer

A study published today in Cell Reports reveals important insights into the molecular mechanisms that underpin the body's natural defenses against the development of skin cancer.

12 Jan 2022

Researchers map the cellular landscape in diabetic foot ulcers

Diabetic foot ulcerations – open sores or wounds that refuse to heal – are a devastating complication affecting more than 15 percent of people with diabetes and resulting in more than 70,000 lower extremity amputations per year in the United States alone.

11 Jan 2022

Research explains how E4 peptide exerts antifibrotic effect and what makes it so effective

A research team at the Medical University of South Carolina led by Carol Feghali-Bostwick, Ph.D., reports in the Journal of Clinical Investigation Insight that the E4 peptide reverses fibrosis, or scarring, in human and mouse tissues by activating an antifibrotic pathway that is common to all organ systems.

11 Jan 2022

Pyroptosis is not a one-way ticket, it can be halted and controlled

A study published by researchers at the University of Illinois Chicago describes a new method for analyzing pyroptosis -; the process of cell death that is usually caused by infections and results in excess inflammation in the body -; and shows that process, long thought to be irreversible once initiated, can in fact be halted and controlled.

11 Jan 2022

Cell Biology

New discovery offers insight into how cells maintain the integrity of DNA

Immune cells in arteries can sniff out their surroundings and cause inflammation

New finding could lead to the development of cell death regulators for cancer therapies

Researchers identify new potential drug target that may block SARS-CoV-2 infection

First molecular images of enzyme may help solve the mystery cause of hereditary neurodegenerative diseases

Research sheds new insights into development of lung macrophages in humans

Moffitt researchers unravel the role of B cells in endometrial cancer

Using E.Coli to bring 3D Printing to Life

Study analyzes the impact of T cells from common cold coronaviruses against SARS-CoV-2 exposure

Researchers determine how key protein drives the defense system to fight viruses

Increasing the expression of a gene slows Alzheimer’s progression in mice

CSHL researchers spotlight the role of a previously little-known protein in leukemia

Scientists discover new Senp5S protein with crucial role in brain development

Targeting MAPK4 in triple-negative breast cancer may lead to improved treatments

New 'disease-in-a-dish' system developed to study oculocutaneous albinism

Researchers reveal molecular and cellular mechanisms that lead to tertiary lymphoid structures formation

Study shows how skin cells act as a firewall against cancer

Researchers map the cellular landscape in diabetic foot ulcers

Research explains how E4 peptide exerts antifibrotic effect and what makes it so effective

Pyroptosis is not a one-way ticket, it can be halted and controlled

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