Cell Biology

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Severe genetic immunodeficiency reversed by a rare DNA change

Researchers have revealed how a rare DNA change rebalanced the immune system of patients with a life-threatening genetic immunodeficiency.

2 Feb 2021

Study discovers new anti-inflammatory role for well-known blood clot protein

Flinders University researchers have discovered a new anti-inflammatory role for well-known blood clot protein fibrinogen, which could support targeted new treatments for kidney, heart and other common diseases.

2 Feb 2021

Researchers study persister cells that go dormant and tolerant to antibiotics

Mehmet Orman, assistant professor of chemical and biomolecular engineering at the University of Houston Cullen College of Engineering, has received a Faculty Early Career Development (CAREER) Award from the National Science Foundation.

2 Feb 2021

Yale scientists discover novel metabolic gatekeeper mechanism for leukemia

In a new study led by Yale Cancer Center, researchers have discovered a novel metabolic gatekeeper mechanism for leukemia. This mechanism depends on a molecule called PON2, which could lead to a new treatment for the disease. The findings were published online today in the Proceedings of the National Academy of Sciences (PNAS).

2 Feb 2021

Some bacteria change their shape to become more adaptive to antibiotics

New research led by Carnegie Mellon University Assistant Professor of Physics Shiladitya Banerjee demonstrates how certain types of bacteria can adapt to long-term exposure to antibiotics by changing their shape.

1 Feb 2021

Study reveals NLRP1 protein that serves as a sensor for invasive pathogens

Researchers are paving the way to a more in-depth understanding of the race between pathogens and the host organisms they search to infect.

29 Jan 2021

Scientists discover the origin of rare genetic syndrome

Improvements in DNA sequencing have revealed a rare syndrome triggered by changes in the SATB1gene.

29 Jan 2021

Targeting glycoprotein could improve response to immune checkpoint therapy

It was an unexpected discovery that started with an analysis of more than 1,000 genes. The question: why game-changing cancer immunotherapy treatments work for only a fraction of patients.

29 Jan 2021

Changes in mitochondria could cause health problems in Space

News-Medical speaks to Dr. Beheshti from NASA about his latest research that investigated whether changes in mitochondria could cause health problems in Space.

From NASA 29 Jan 2021

Study shows TALEN is five times more efficient than CRISPR-Cas9 tool

Using single-molecule imaging, scientists have compared the CRISPR-Cas9 and TALEN genome editing tools.

28 Jan 2021

Study shows how stem cell niche maintain their self-renewal capacity

A typical trait of all stem cells is their potential to renew on their own; however, scientists are unsure about how this ability is sustaining throughout life.

28 Jan 2021

Genetic changes in tumors could help predict patient's response to immunotherapy drugs

Researchers at the Francis Crick Institute, the UCL Cancer Institute, and the Cancer Research UK Lung Cancer Centre of Excellence have identified genetic changes in tumours which could be used to predict if immunotherapy drugs would be effective in individual patients.

28 Jan 2021

Unique proteomics-based technology can help diagnose breast cancer more accurately

Breast cancer could be identified more precisely than existing methods using blood specimens and exclusive proteomics-based technology.

28 Jan 2021

Mice study provides new data for studying aging and age-related diseases

A novel compound that increases lifespan in a small nematode worm has been shown to delay bone loss in aging mice.

28 Jan 2021

Researchers identify a new compound for creating a new class of diabetes drugs

A new study headed by the Ohio State University Wexner Medical Center and the College of Medicine has found a new compound that could form the base for creating a new class of diabetes drugs.

28 Jan 2021

Study shows how abnormal number of chromosomes could become a weak point for cancer cells

What makes cancer cells different from ordinary cells in our bodies? Can these differences be used to strike at them and paralyze their activity?

28 Jan 2021

New technique replicates bone tissue complexity and bone remodeling processes

A multidisciplinary team of researchers at the University of Massachusetts Amherst's Institute for Applied Life Sciences (IALS) have developed a technique to replicate bone tissue complexity and bone remodeling processes.

27 Jan 2021

Two enzymes drive pre-cancer stem cells into malignancy

Since stem cells can continually self-regenerate, making more stem cells, and differentiate into many different specialized cell types, they play an important role in our development and health.

From UC San Diego 27 Jan 2021

Study shows why obese mothers tend to have children susceptible to metabolic diseases

A Brazilian study published in the journal Molecular Human Reproduction helps understand why obese mothers tend to have children with a propensity to develop the metabolic disease during their lifetime, as suggested by previous research.

27 Jan 2021

Study shows two phases of wall restructuring after an aneurysm forms

Hitting a pothole on the road in just the wrong way might create a bulge on the tire, a weakened spot that will almost certainly lead to an eventual flat tire. But what if that tire could immediately begin reknitting its rubber, reinforcing the bulge and preventing it from bursting?

27 Jan 2021