Cell Biology

RSS

Exploring cell and gene based therapies for Parkinson’s disease

After several decades of pre-clinical development, cell- and gene-based therapies for Parkinson's disease (PD) are now actively being explored. In this special supplement to the Journal of Parkinson's Disease on "Repairing the Parkinsonian Brain," experts highlight some of the current strategies being pursued to restore lost function and replace what is lost in the PD brain, with special emphasis on the challenges associated with translating advanced therapeutic approaches into pioneering clinical trials.

24 Sep 2021

Researchers identify host entry factor for Rift Valley fever virus

Rift Valley fever virus causes economically devastating outbreaks of hemorrhagic fever in livestock such as sheep, goats and cattle. These mosquito-borne outbreaks lead to infection in people working with dead or dying animals, sometimes causing hundreds of human cases and dozens of deaths.

24 Sep 2021

New map provides a reference to predict which antibodies are effective against SARS-CoV-2

Scientists at La Jolla Institute for Immunology have published a detailed map of where human antibodies bind to SARS-CoV-2, a map that was generated by a global collaboration comparing nearly all leading clinical candidates.

24 Sep 2021

How do genetic variants influence the expression of genes in the blood?

Researchers are now pursuing intensive research on the genetic causes of traits and diseases, with over 250,000 such links known currently.

24 Sep 2021

How does the KLF4 transcription factor influence gene expression?

Scientists have led a research group to identify a mechanism using which transcription factor KLF4 can influence gene expression.

24 Sep 2021

Circulating tumor cells found to form clusters that cause breast cancer metastases

A new study reports that circulating tumor cells that exhibit the features of stem cells employ ICAM1 to enable the formation of CTC clusters.

24 Sep 2021

Discovery may offer a promising new path for the study of multiple sclerosis

A surprising discovery may offer a promising new direction in the study of multiple sclerosis and other diseases of hypomyelination – when axons of neurons are not covered sufficiently in fatty sheaths (myelin), which disrupts communication between nerve cells.

23 Sep 2021

Microglial cells join together to break down toxic proteins more quickly

To break down toxic proteins more quickly, immune cells in the brain can join together to form networks when needed. This is shown by a joint study of the University of Bonn, the German Center for Neurodegenerative Diseases, and the Institut François Jacob in France.

23 Sep 2021

Naturally occurring protein that blocks inflammatory response linked to better stroke recovery in mice

A naturally occurring protein that blocks an inflammatory immune response was associated with better stroke recovery in a study conducted in mice, according to preliminary research to be presented at the American Heart Association's Vascular Discovery: From Genes to Medicine Scientific Sessions 2021.

23 Sep 2021

Researchers provide novel treatment target for common skin condition

Recent research indicates that a familiar inflammatory skin condition might arise due to inadequately regulated sex hormones.

23 Sep 2021

Experts explore the organization of cancer cells and the influence of drug treatment

The changes that occur in individual cancer cells in due course detail the varied development of brain tumors.

23 Sep 2021

Premature aging of the tracheobronchial stem cells could contribute to chronic lung disease

Are prematurely aged or overworked stem cells a significant factor in chronic lung disease? Findings of a study just released in STEM CELLS Translational Medicine (SCTM) say this is likely so.

22 Sep 2021

CSHLP releases new book on the arsenal of memory T-cells

Cold Spring Harbor Laboratory Press (CSHLP) announced the release of T-Cell Memory, available on its website in hardcover and eBook formats.

21 Sep 2021

Scientists find two proteins that pair up to build lifelines to cancer cells

In human cancer cell and mouse studies, researchers from Johns Hopkins Medicine have found that a set of proteins work in tandem to build supply lines that deliver oxygen and nutrients to tumors, enabling them to survive and grow.

21 Sep 2021

Researchers find a new way to counter immunosuppressive effect in tumors

Malignant tumors can enhance their ability to survive and spread by suppressing antitumor immune cells in their vicinity, but a study led by researchers at Weill Cornell Medicine and NewYork-Presbyterian has uncovered a new way to counter this immunosuppressive effect.

21 Sep 2021

Cell Biology

Exploring cell and gene based therapies for Parkinson’s disease

Researchers identify host entry factor for Rift Valley fever virus

New map provides a reference to predict which antibodies are effective against SARS-CoV-2

How do genetic variants influence the expression of genes in the blood?

How does the KLF4 transcription factor influence gene expression?

Circulating tumor cells found to form clusters that cause breast cancer metastases

Discovery may offer a promising new path for the study of multiple sclerosis

Microglial cells join together to break down toxic proteins more quickly

Naturally occurring protein that blocks inflammatory response linked to better stroke recovery in mice

Researchers provide novel treatment target for common skin condition

Experts explore the organization of cancer cells and the influence of drug treatment

Premature aging of the tracheobronchial stem cells could contribute to chronic lung disease

CSHLP releases new book on the arsenal of memory T-cells

Scientists find two proteins that pair up to build lifelines to cancer cells

Researchers find a new way to counter immunosuppressive effect in tumors

Research details previously unknown biological process—cell patterning

Automated computer program counts micronuclei from images of stained cells

Study outlines the advantages of organoids for basic research into coronaviruses

New chemical could help reluctant seeds to spring to life

Researchers identify a manipulation molecule produced by bacteria to hijack plant development

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Latest in Genomics