Cell Biology

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New insights on an enzyme complex involved in plaque production

A research team led by Wim Annaert (VIB-KU Leuven) uncovered the early assembly of gamma-secretase, a protein complex linked to numerous cellular processes including the development of Alzheimer's disease.

23 Jul 2021

New transferrable and integrative type I CRISPR-based platform to efficiently edit superbugs

A research team led by Dr Aixin YAN, Associate Professor from the Research Division for Molecular & Cell Biology, Faculty of Science, in collaboration with Honorary Clinical Professor Patrick CY WOO from the Department of Microbiology, Li Ka Shing Faculty of Medicine, the University of Hong Kong, reported the development of a transferrable and integrative type I CRISPR-based platform.

23 Jul 2021

Study reveals SARS-CoV-2 variant is less sensitive to inhibition by antibodies

SARS-CoV-2 is still a major threat to humankind. The constant emergence of variants makes the threat made by the virus difficult to estimate. The SARS-CoV-2 variant B.1.617 spread in India and gave rise to the Delta variant, B.1.617.2, which is now dominant in numerous countries.

23 Jul 2021

Research identifies vitamin C as a key ingredient for immune cell function

A new study has now identified that it is not possible to generate stable regulatory T cells without Vitamin C or enzymes called TET proteins as much as how one cannot make a banana split without bananas.

23 Jul 2021

SARS-CoV-2 variant B.1.617 can infect lung and intestinal cells more efficiently than the original virus

SARS-CoV-2 still poses major challenges to mankind. The frequent emergence of mutant forms makes the threat posed by the virus difficult to predict.

22 Jul 2021

New study uncovers how enterococcal cytolysins affect cells

Although Enterococcus faecalis is usually an innocuous member of the bacterial community in the human gut, it can also cause several infections, including liver disorders. The bacteria produce cytolysins, which are molecules that destroy cells. In a new study, researchers have uncovered how they do so.

22 Jul 2021

Researchers discover nucleotide sequences characteristic of microRNA isoforms

Researchers from HSE University have discovered nucleotide sequences characteristic of microRNA isoforms (microRNAs with errors).

22 Jul 2021

New test to detect substances that are harmful to the placenta and embryo

Researchers at ETH Zurich have developed a cell culture test to detect substances that are directly or indirectly harmful to embryos. Based on an existing test used for developing new drugs and chemicals, the augmented version is designed to help reduce the number of animal experiments.

22 Jul 2021

Cell couriers offer clue to how cancers metastasize into secondary tumors

A protein involved in making cells move offers a clue to how certain types of cancer metastasize and develop into secondary tumors, according to new research from the University of Warwick.

From The University of Warwick 22 Jul 2021

L452R mutation of SARS-CoV-2 spike protein is involved in cellular immunity evasion

A research team has demonstrated that the L452R mutation of the SARS-CoV-2 spike protein plays a role in cellular immunity evasion.

21 Jul 2021

Study identifies many small molecules that bind to certain areas of the SARS-CoV-2 genome

Scientists at Goethe University have now identified some regions of the SARS-CoV-2 genome that might be an ideal target for future drugs.

21 Jul 2021

Study unravels gene expression control mechanism with immunity and cancer implications

Despite alternative polyadenylation (APA) affecting a larger part of human genes, the importance of APA was not well understood.

21 Jul 2021

Modification in some RNA molecules could protect against non-alcoholic fatty liver

RNA molecules while carrying genetic instructions from DNA to the protein-making machinery of cells could help guard against non-alcoholic fatty liver.

21 Jul 2021

Study identifies a signaling protein that controls the assembly of mitochondria

Scientists from the University of Freiburg have identified a signaling protein that regulates the assembly of human cellular “power plants.”

21 Jul 2021

New study could prevent T cell exhaustion in the immune system’s fight against cancer

Struggling against a tumor is not a sprint. It is a marathon. The race of cancer-fighting T cells is at times simply very long, and the T cells give up fighting. This phenomenon is referred to as T cell exhaustion by researchers.

21 Jul 2021

Study shows astrocytes induce sex differences during brain development

Scientists have found that when brain cells develop, they may find various ways to link with each other based on sex.

21 Jul 2021

Research substantiates nanoparticles as promising platforms for cell nano-sensors

Researchers published an article that represents the transmission electron microscopy (TEM) and flow cytometry study of A-549 (human lung carcinoma) cellular uptake of Pr3+:LaF3 nanoparticles.

21 Jul 2021

Study unravels the biomechanical, biophysical response of cancer cells to drugs

A new study reports the use of single-cell, force spectroscopy methods to probe biophysical and biomechanical kinetics of cancer cells.

21 Jul 2021

Study shows how single cells take up fatty acids, offering new insights into cancer biology

Researchers have developed a new method that offers novel insights into cancer biology by enabling them to unravel how single cells absorb fatty acids.

21 Jul 2021

Atomic force spectroscopy probes cellular biomechanics in response to drugs in hypoxia

Oncotarget published "Dynamic cellular biomechanics in responses to chemotherapeutic drug in hypoxia probed by atomic force spectroscopy" which reported that by exploiting single-cell, force spectroscopy methods, the authors probed biophysical and biomechanical kinetics of brain, breast, prostate, and pancreatic cancer cells with standard chemotherapeutic drugs in normoxia and hypoxia over 12-24 hours.

20 Jul 2021

Cell Biology

New insights on an enzyme complex involved in plaque production

New transferrable and integrative type I CRISPR-based platform to efficiently edit superbugs

Study reveals SARS-CoV-2 variant is less sensitive to inhibition by antibodies

Research identifies vitamin C as a key ingredient for immune cell function

SARS-CoV-2 variant B.1.617 can infect lung and intestinal cells more efficiently than the original virus

New study uncovers how enterococcal cytolysins affect cells

Researchers discover nucleotide sequences characteristic of microRNA isoforms

New test to detect substances that are harmful to the placenta and embryo

Cell couriers offer clue to how cancers metastasize into secondary tumors

L452R mutation of SARS-CoV-2 spike protein is involved in cellular immunity evasion

Study identifies many small molecules that bind to certain areas of the SARS-CoV-2 genome

Study unravels gene expression control mechanism with immunity and cancer implications

Modification in some RNA molecules could protect against non-alcoholic fatty liver

Study identifies a signaling protein that controls the assembly of mitochondria

New study could prevent T cell exhaustion in the immune system’s fight against cancer

Study shows astrocytes induce sex differences during brain development

Research substantiates nanoparticles as promising platforms for cell nano-sensors

Study unravels the biomechanical, biophysical response of cancer cells to drugs

Study shows how single cells take up fatty acids, offering new insights into cancer biology

Atomic force spectroscopy probes cellular biomechanics in response to drugs in hypoxia

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