Cell Biology

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New bioluminescent reporter tracks DNA double stranded break repair in cells

A new bioluminescent reporter that tracks DNA double stranded break (DSB) repair in cells has been developed by researchers from Massachusetts General Hospital (MGH) and the Academia Sinica in Taiwan.

24 Aug 2020

Study provides a SnapShot of FABP proteins linked to obesity

Fatty acid-binding proteins (FABPs), function as a kind of chaperone, synchronizing the transport of various molecules, including fatty acids, between cells.

24 Aug 2020

Study sheds new light on crucial proteins linked to genetic diseases

A new study offers a better understanding of the properties of important proteins found inside the ciliary membrane.

24 Aug 2020

Eliminating tumors with engineered ‘off-the-shelf’ therapeutic T cells

Personalized cancer treatments are no longer just options of the future. In the past few years, researchers have made significant progress in 'teaching' the body's immune T cells to recognize and kill specific cancer cells, and human clinical trials have shown that this approach can successfully eliminate tumors

21 Aug 2020

A metabolic enzyme could be potential target for immunotherapies

The metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system.

21 Aug 2020

Study offers promising data for improved treatments for cardiac disease

A group of researchers have recently published an article that provides promising data for enhanced therapeutic treatments for cardiac disease.

20 Aug 2020

Study shows how PIM kinases enhance the motility of cancer cells

PIM kinases are essentially enzymes that support the metastatic growth and proliferation of tumor cells.

20 Aug 2020

Newly developed transplantable human cells can help cure type 1 diabetes

Researchers have made a significant advancement in the quest for a safe, effective treatment for type 1 diabetes.

20 Aug 2020

Small set of genes may help decide the identity of every neuron in worms

When it comes to brain cells, one size does not fit all. Neurons come in a wide variety of shapes, sizes, and contain different types of brain chemicals.

20 Aug 2020

Improving the accuracy of DNA melt curve

DNA is not only the blueprint of life, it has become the backbone for making tiny structures that can be inserted into the human body to diagnose and treat disease.

20 Aug 2020

Cytokine storms in COVID-19 patients may prevent the development of long-term immunity

Shiv Pillai, MD, Ph.D., investigator in the Ragon Institute of MGH, MIT and Harvard and professor at Harvard Medical School (HMS), recently published a paper in Cell showing that that high levels of some cytokines seen in COVID-19 patients, as part of a cytokine storm, may prevent the development of long-term immunity to SARS-CoV-2, the virus that causes COVID-19.

20 Aug 2020

Disrupted brain remapping causes spatial memory impairment in Alzheimer's

Alzheimer's disease is one of the most serious diseases in an aging society, yet the cause is often unclear and there is no appropriate treatment method.

20 Aug 2020

Researchers identify a new type of PII-like proteins in Lactobacillus hilgardii LMG 7934

The team is led by Associate Professor Ayrat Kayumov (Department of Genetics, Kazan Federal University). In this research, the scientists not only performed genome sequencing, but also found a completely new type of PII-Like Protein PotN.

20 Aug 2020

UT researchers to explore the mysteries of brain connections

Researchers at The University of Texas at Austin will lead an ambitious new project with 10 other U.S. institutions and global partners that has significant implications for understanding human brain health.

20 Aug 2020

Study reveals a mechanism for lower-quality immune response in patients with severe COVID-19

The release of massive amounts of proteins called cytokines can lead to some of the most severe symptoms of COVID-19.

From Harvard Medical School 20 Aug 2020

Removing copper from the blood can destroy some of the deadliest cancers

Australian researchers have discovered that removing copper from the blood can destroy some of the deadliest cancers that are resistant to immunotherapy using models of the disease.

20 Aug 2020

Researchers identify key protein involved in age-related disorders

People may go to great lengths to fight aging, but this process is a part of life.

From Osaka University 20 Aug 2020

Study shows age is a major risk factor for dying from COVID-19 infection

According to a study, genes that play a significant role in enabling SARS-CoV-2 to penetrate the heart cells become more active as people age.

20 Aug 2020

Gene targeting could lead to better treatment of glioblastoma tumors

New insight into a gene that controls energy production in cancer stem cells could help in the search for a more effective treatment for glioblastoma.

19 Aug 2020

Shielded stem cells can improve heart healing

Ghanta, R.K., et al. (2020) Immune-modulatory alginate protects mesenchymal stem cells for sustained delivery of reparative factors to ischemic myocardium. Biomaterials Science. doi.org/10.1039/D0BM00855A.

19 Aug 2020