Cell Biology

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Researchers discover protein that may trigger lung scarring

Systemic sclerosis is an autoimmune disease associated with inflammation and fibrosis, or scarring, that affects organs including the skin, heart, kidney and lungs.

18 Dec 2020

Scientists find new way to prevent cancer relapse after immunotherapy

Mount Sinai researchers have solved one of the enduring mysteries of cancer immunotherapy: Why does it completely eliminate tumors in many patients, even when not all the cells in those tumors have the molecular target that the therapy is aimed at?

18 Dec 2020

Innovative gene therapy approach for regeneration of functional new neurons

Spinal cord injury (SCI) often causes disability and seriously compromises quality of life. While decades of research have made significant progress in axonal regeneration after SCI, most of the interventions have not been translated into clinical therapies.

18 Dec 2020

Study reveals correlations between genes and cellular pathways in the brain

You must first understand how something works normally before you can figure out why it's broken.

17 Dec 2020

New model shows how the brain uses "gating" phenomenon to control information

Getting computers to "think" like humans is the holy grail of artificial intelligence, but human brains turn out to be tough acts to follow. T

17 Dec 2020

New study targets small proteins in Salmonella to combat the pathogen

Salmonella is a type of bacteria that causes food poisoning upon infection, with acute diarrhea.

17 Dec 2020

Scientists identify new target to deliver anti-cancer drugs to tumor cells

With the evolution of cancer, the quest for identifying efficient treatment techniques for cancer patients has remained challenging.

17 Dec 2020

Study may lead to new treatments for certain types of disease

Researchers at the Francis Crick Institute have found a new way to prevent some tumours from repairing their own DNA, a function that is essential for cancer cell survival. This discovery could lead to much needed new treatments for certain types of the disease.

17 Dec 2020

Researchers detect new immune cells that act as major driver of breast cancer growth

Several breast cancer immunotherapies have had only minimal success in treating the aggressive forms of this disease.

17 Dec 2020

Study: Fungi have proteins that allow them to sense consumable things

According to a new study, the same proteins responsible for enabling human senses, like smell, also enable some fungi to sense things they can consume.

17 Dec 2020

Study: DOT1L enzyme is essential for humoral immune responses

Communication, serendipity and an enzyme called DOT1L have all combined to produce some exciting findings into the immune system's B cells and T cells by two groups of Monash Biomedicine Discovery Institute (BDI) scientists.

17 Dec 2020

Researchers discover genetic variants of host proteins involved in SARS-CoV-2 infection

Like all viruses, the novel coronavirus is dependent on help from the human host cell. Proteins are the functional units of the cell and enable the virus to enter the host cell or help the virus to replicate.

17 Dec 2020

Plastics contain endocrine-disrupting chemicals that threaten human health, shows new report

Plastics contain and leach hazardous chemicals, including endocrine-disrupting chemicals (EDCs) that threaten human health.

16 Dec 2020

Dermal odontodes arise from the same developmental system, shows study

Teeth and hard structures called dermal odontodes are evolutionarily related, arising from the same developmental system, a new study published today in eLife shows.

16 Dec 2020

Study: Eating avocado as part of daily diet can help improve gut health

Eating avocado as part of your daily diet can help improve gut health, a new study from University of Illinois shows. Avocados are a healthy food that is high in dietary fiber and monounsaturated fat. However, it was not clear how avocados impact the microbes in the gastrointestinal system or "gut."

16 Dec 2020

Biochemical methods reveal signal transduction mystery inside human pathogen

In order to adapt to the changing environment, bacteria must quickly transform extracellular information into appropriate intracellular reactions. Two component system (TCS) is the main signal transduction protein in prokaryotic cells to transform environmental stimuli into cellular responses.

16 Dec 2020

Study may lead to new approaches to protect older individuals from viruses

A drug that boosts the removal of cellular debris in immune cells may increase the protective effects of vaccines in older adults, a study published today in eLife shows.

16 Dec 2020

Tumor's stiff-arm tactic restricts the effectiveness of checkpoint inhibitors

In a paper just published in the Journal for the Immunotherapy of Cancer (doi:10.1136/jitc-2020-001712), Dr. Herbert, Head of Discovery at InsideOutBio, asks whether cancer cells stiff-arm immune cells just like rugby players push off defenders from the other team.

16 Dec 2020

Imperfect egg cells more common than originally thought

AZoLifeSciences speaks to Dr. Terry Hasssold about his latest research into oocytes and how imperfect egg cells are more common than scientists initially thought.

16 Dec 2020