Cell Biology

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Study Finds Essential Role of Orco Protein in Ant Olfactory Neuron Survival and Social Interaction

While smell plays a considerable role in the social interactions of humans-;for instance, signaling fear or generating closeness-;for ants, it is vitally important.

10 Jun 2024

Study Unveils Broader Immune Response in EBV-MS Connection

Epstein-Barr virus (EBV) may have a greater effect on the development of multiple sclerosis (MS) than previously believed due to a higher level of cross-reactivity, which occurs when the immune system binds to the incorrect target.

10 Jun 2024

Multiciliated Cell Differentiation Regulated by an Alternative Cell Cycle

A fertilized egg can develop into a baby through the amazing process of cell division, while a malignant cell can become a malignant tumor. Since there is so much on the line, nature maintains strict control over it through a mechanism known as the cell cycle that scientists once believed they thoroughly understood.

7 Jun 2024

Unraveling the Mysteries of Killifish Embryonic Development

The annual killifish lives in regions with extreme drought. A research group at the University of Basel now reports in "Science" that the early embryogenesis of killifish diverges from that of other species.

7 Jun 2024

Columbia Studies Uncover Misidentification of Gut Stem Cells

Two independent studies by Columbia scientists suggest that research into the gut's stem cells over the past 15 years has been marred by a case of mistaken identity: Scientists have been studying the wrong cell.

7 Jun 2024

Cellular Architecture Dictates T Cell Fate in Immune Response

From the outside, most T cells look the same: small and spherical. Now, a team of researchers led by Berend Snijder from the Institute of Molecular Systems Biology at ETH Zurich has taken a closer look inside these cells using advanced techniques.

7 Jun 2024

Critical NPC Protein Nup358 Linked to Myeloid Disorders

Nuclear pore complexes (NPCs) are channels composed of multiple proteins that ferry molecules in and out of the nucleus, regulating many critical cellular functions, such as gene expression, chromatin organization and RNA processes that influence cell survival, proliferation, and differentiation.

6 Jun 2024

Breakthrough Study Identifies Critical Protein for Blood Stem Cell Self-Renewal

UCLA scientists have identified a protein that plays a critical role in regulating human blood stem cell self-renewal by helping them sense and interpret signals from their environment.

6 Jun 2024

Study Unveils Key Mechanism of Telomere Maintenance by CST–Polα/Primase

The length of telomeres that protect the ends of our chromosomes should be tightly regulated. Those that are too long predispose to cancer, and those that are too short lose their protective ability, resulting in telomere disorders with serious health consequences.

6 Jun 2024

Coordinated Proteins Aid the Immune System in Detecting and Destroying Threats

Bacteria, parasites, and viruses—the immune system tackles them all. Cells known as macrophages are at the forefront of the human immune response, recognizing intruders and controlling how the entire immune system responds.

6 Jun 2024

How Tumor-Associated Fibrosis Shapes Immune Responses

Immunotherapy is based on harnessing a person's own immune system to attack cancer cells. However, patients with certain tumors do not respond to these therapies and it remains unclear why.

5 Jun 2024

Exploring the Dynamic Interactions of Circadian Clock Proteins

Circadian clocks, which drive circadian rhythms, are entwined with many essential systems in living things including plants, fungi, insects, and even humans.

5 Jun 2024

High-Accuracy DNA Methylation Clocks Illuminate Age-Related Changes in Primate Ovaries

The ovary is an essential organ for female fertility, and its age-dependent decline in function is a major cause of infertility.

5 Jun 2024

UC San Diego Researchers Find Cause of Cellular 'Short-Circuit'

A group of researchers at University of California San Diego has identified the cause of a "short-circuit" in cellular pathways, a discovery that sheds new light on the genesis of a number of human diseases.

5 Jun 2024

Unveiling Age-Related Lipid Alterations

Researchers from the RIKEN Center for Integrative Medical Sciences (IMS) revealed various age-related alterations in mice's lipid metabolism, across both organs and sexes.

5 Jun 2024

Researchers Identify Molecular Stop Signal in Cell Division Monitoring

Every second, many million cells divide throughout the body. During nuclear division (mitosis), the genetic material must be divided correctly and fully amongst daughter cells; faults in this process can result in improper development or genetic diseases, and many cancer cells have an uneven number of chromosomes.

5 Jun 2024

Researchers Advance Single-Molecule DNA Sequencing Techniques

In recent years, technologies that allow scientists to investigate a person's DNA at single-molecule resolution have greatly increased the knowledge of the human genome, microbiome, and the genetic basis of disease.

5 Jun 2024

Sphere Fluidics Launches Cyto-CellectPLUS to Accelerate Cell Line Development Workflows

Sphere Fluidics, a leading provider of innovative microfluidics-based solutions for single-cell analysis and isolation, today announced the launch of Cyto-Cellect®PLUS.

From Sphere Fluidics Limited 5 Jun 2024

Exploring Hepatic and Serum Proteomic Signatures in Werner Syndrome Mice

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 10, entitled, "Integrated liver and serum proteomics uncover sexual dimorphism and alteration of several immune response proteins in an aging Werner syndrome mouse model."

4 Jun 2024