Cell Biology

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Mapping Gene Signatures Unveils How Lewy Bodies Impact Brain Cells

A new study by scientists at Van Andel Institute provides an initial glimpse into the intricate molecular changes taking place in brain cells with Lewy bodies, crucial pathological markers of Parkinson’s disease and certain dementias.

17 Apr 2024

Mysterious Plasmid in Human Gut Holds Potential for Health Hazard Detection

A component of the human intestinal flora that has been little studied to date is the focus of a new study.

17 Apr 2024

First Single-Cell Atlas for the Water Nymph Worm Published

An international team of scientists including B. Duygu Özpolat at Washington University in St. Louis has published the first single-cell atlas for Pristina leidyi (Pristina), the water nymph worm, a segmented annelid with extraordinary regenerative abilities that has fascinated biologists for more than a century.

16 Apr 2024

Exercise Intervention Reduces Fat Accumulation Associated with Aging

Scientists have discovered that a type of fat accumulates as tissue ages and that this accumulation can be reversed through exercise.

16 Apr 2024

Newly discovered mechanism identified in the initial stages of Alzheimer's disease

Alzheimer's disease (AD) continues to be one of the most difficult and common neurodegenerative diseases, impacting millions of people globally.

16 Apr 2024

New Delivery System Opens the Door to Gene-Silencing Therapy

The next generation of medications, known as antisense oligonucleotides (ASOs), works by preventing the transmission of damaging genetic messages.

16 Apr 2024

Nasal Cells in Children Shield Against Severe COVID-19

Children usually have milder COVID-19 symptoms; this could be due to differences in how elderly and young people's nasal cells react to the SARS-CoV-2 virus.

16 Apr 2024

Cell's Garbage Disposal May Also Send Sensory Signals Beyond Recycling

The proteasome, the cell's garbage disposal mechanism, usually breaks down proteins into smaller pieces and recycles some of the pieces.

15 Apr 2024

Spinal Cord's Hidden Role in Learning Movement

A common misconception is that the spinal cord serves as a basic relay station that transmits signals from the brain to the body.

15 Apr 2024

Research Uncovers Genetic Basis of Macroalgae Multicellularity

A deep dive into macroalgae genetics has uncovered the genetic underpinnings that enabled macroalgae, or "seaweed," to evolve multicellularity.

15 Apr 2024

Study Reveals How Cells Recycle Proteins in Response to Nutrient Starvation

A new study details how nutrient-starved cells divert protein transport stations to cellular recycling centers to be broken down, highlighting a novel approach cells use to deal with stressful conditions.

15 Apr 2024

Genomic Deletions Drive Development of Melanoma Drug Resistance

Melanoma is the deadliest form of skin cancer. With global incidence rates rising, new, more effective treatments are necessary to alleviate the health burden of the disease. Important advances in recent years include doctors using genetic tests to look for specific mutations they can target for more personalised, effective treatment.

15 Apr 2024

OrthoID Method Revolutionizes Protein Identification in Organelle Communication

A collaboration between POSTECH, Daegu Catholic University School of Medicine, and Seoul National University unveils a novel strategy for identifying key proteins in organelle communication.

15 Apr 2024

Study Offers Valuable Insights Into Mutagenesis Mechanisms and Cancer Evolution

Mutations are the changes in the DNA that gradually occur in human cells as they replicate, and the organism grows and ages.

13 Apr 2024

How Glucocorticoids Quell Inflammation

Cortisone and other related glucocorticoids are extremely effective at curbing excessive immune reactions.

13 Apr 2024

Unraveling the Molecular Mechanisms of DNA Entanglement Resolution

Picture in your mind a traditional "landline" telephone with a coiled cord connecting the handset to the phone.

12 Apr 2024

Different Chromosomes Found to Have Separate End-Specific Telomere-Length Distributions

We depend on our cells being able to divide and multiply, whether it's to replace sunburnt skin or replenish our blood supply and recover from injury.

12 Apr 2024

Unlocking Bacterial Dormancy: Polyphosphates' Role Revealed

Most disease-causing bacteria are known for their speed: In mere minutes, they can double their population, quickly making a person sick.

12 Apr 2024

Nutrient Deprivation Induces Embryonic Diapause in Hungry Mouse Mums

It's challenging to sustain a pregnancy when food is short, or conditions are otherwise tough. That's why many mammalian embryos can postpone their growth to get through periods of environmental stress and then re-enter development when conditions improve.

12 Apr 2024

Cellular Insights Into Facial Morphogenesis

Mother Nature is an artist, but her craft of creating animal faces requires more than a paintbrush and palette. Such highly complex shapes originate from their respective transient neural crest cells.

12 Apr 2024