Cell Biology

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Glutamate tRNA Fragments Play Key Role in Brain Aging and Alzheimer's Disease

A significant research paper published in the journal Cell Metabolism by the team of Prof. LIU Qiang at the University of Science and Technology of China (USTC) reveals the critical role of glutamate tRNA fragments in brain aging and Alzheimer's disease.

14 May 2024

Decoding Chromatin Modifications: A Breakthrough in Epigenome Editing

An epigenome editing platform and a method to program nine major chromatin modifications.

14 May 2024

Study Reveals the Surprising Role of Spliceosomes in Introns' Journey

Although you may not appreciate them, or have even heard of them, throughout your body, countless microscopic machines called spliceosomes are hard at work.

13 May 2024

Unraveling the Molecular Landscape of Parietal Cell Development

Common conditions such as indigestion and heartburn as well as peptic ulcers, autoimmune gastritis and stomach and esophageal cancers have one thing in common – they involve disruptions of the normal activity of parietal cells (PCs) in the stomach, the only cells in the body that produce acid.

13 May 2024

New Study Links Macrophage Diversity with Patient Survival

Researchers at the National University of Singapore (NUS)'s Cancer Science Institute of Singapore (CSI) have made significant progress in the understanding of the recurrence following chemotherapy for diffuse large B-cell lymphoma (DLBCL), a particular type of cancer.

13 May 2024

New Population of Cells in Human Omental Fat Tissue Found to Hinder Adipogenesis

Understanding how fat tissue forms and functions is crucial for addressing obesity and related metabolic diseases. However, adipose tissue, or body fat, behaves differently based on its location in the body.

10 May 2024

Decoding Aging: The Role of Stochastic Variation in Biological Clocks

Aging clocks can measure the biological age of humans with high precision. Biological age can be influenced by environmental factors such as smoking or diet, thus deviating from the chronological age that is calculated using the date of birth.

10 May 2024

AI Deciphers the Complex Wiring of the Human Brain

Though it may not seem like much, one cubic mm of brain tissue exists. That small square, however, holds 230 mm of blood vessels, 150 million synapses, and 57,000 cells, totaling 1,400 terabytes of data. That is why researchers from Google and Harvard have just achieved something truly amazing.

10 May 2024

UCLA Study Reveals Novel Mechanism for Memory Formation During Sleep

UCLA Health researchers have discovered a mechanism that creates memories while reducing metabolic cost, even during sleep.

9 May 2024

Study Reveals Dual Contractility Modes in Cancer Cell Invasion

Understanding how cancerous cells spread from a primary tumor is important for any number of reasons, including determining the aggressiveness of the disease itself.

8 May 2024

Fruit Fly Model Unveils Hidden Mechanisms of Organ Development

A new computational model simulating fruit fly wing development has enabled researchers to identify previously hidden mechanisms behind organ generation.

8 May 2024

mRNA Dynamics Guide Cell Identity Formation

New research from Hebrew University sheds light on the regulation of mRNA during the development of the embryo. The research separates newly-transcribed from pre-existing mRNA in zebrafish embryos using a combination of single-cell RNA-Seq and metabolic labeling.

8 May 2024

Herpesvirus Infection Reshapes Mitochondrial Architecture and Disrupts Metabolic Processes

Herpesvirus infection alters the host cell's mitochondria's normal structure and function, according to researchers from the University of Jyväskylä.

8 May 2024

Researchers Pinpoint Neural Compass Crucial for Navigation

A pattern of brain activity that helps prevent us from getting lost has been identified in a new study, published in Nature Human Behaviour.

7 May 2024

Harnessing Gut Microbiome Compounds to Reduce Inflammation

Researchers at the University of Toronto have found naturally occurring compounds in the gut that can be harnessed to reduce inflammation and other symptoms of digestive issues.

6 May 2024

Unlocking Glucose-Driven Mechanisms of Immunosuppression in Glioblastoma

The Wistar Institute assistant professor Filippo Veglia, Ph.D., and team, have discovered a key mechanism of how glioblastoma -; a serious and often fatal brain cancer -; suppresses the immune system so that the tumor can grow unimpeded by the body's defenses.

6 May 2024

Protein Complex Movement May Regulate Cell Division, Impacting Disease Research

Scientists at Umeå University in Sweden have found that the movement of a unique protein complex known as the Mediator along DNA genes may affect the process of cell division.

6 May 2024

Study Demonstrates How the Warburg Effect is Crucially Linked to Cancer Progression

Researchers have revealed crucial insights into how the Warburg effect causes the dedifferentiation of cancer cells through epigenetic reprogramming.

3 May 2024

Unveiling the Role of NCLX Protein in Mitochondrial Calcium Regulation and Autophagy

An article published in The Faseb Journal describes a Brazilian study analyzing the correlation between two key energy metabolism regulation processes: the absorption and release of calcium ions by mitochondria, the organelles that generate energy for cells; and autophagy induced by calorie restriction.

3 May 2024