Cell Biology

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Metabolite from pomegranate to boost immune cells that fight tumors

Researchers from the Georg-Speyer-Haus in Frankfurt am Main, Germany, and Goethe University Frankfurt have succeeded in developing a new strategy for the treatment of colorectal cancer as part of an interdisciplinary initiative of the LOEWE Center Frankfurt Cancer Institute (FCI).

28 Oct 2022

Immunological mechanisms behind the development of alloantibodies

Hemophilia A is the most frequent severe variant of hemophilia. It nearly mostly affects men. The condition is frequently treatable, although not for all patients. A study at the University of Bonn has now highlighted a critical mechanism required for the therapy to be efficient.

28 Oct 2022

Novel technology accurately analyzes cell properties

The potential to examine the features of individual cells is critical in a diverse spectrum of life science applications, from disease diagnosis and therapeutics to identifying pathogenic bacteria and generating cells for bioproduction.

28 Oct 2022

Pioneering gene editing approach could lead to new treatments for CTLA-4 insufficiency

A fault in cells that form a key part of the immune system can be repaired with a pioneering gene editing technique, finds new research demonstrated in human cells and mice, led by UCL scientists.

From University College London 27 Oct 2022

Many proteins share important roles in the formation and function of synapses, study finds

Not just three, but even five proteins share important roles in the formation and function of synapses and can substitute for each other. This discovery was made by a team of the research focus "Mental Health & Neuroscience" of the Karl Landsteiner University of Health Sciences Krems (KL Krems) and the CavX PhD program of the Medical University of Innsbruck.

26 Oct 2022

Innovative strategy for studying membrane proteins

Membrane proteins are vital therapeutic targets. They exist between the interior and exterior of human cells. Some of them, known as “transporters,” transport substances into and out of the cellular environment.

26 Oct 2022

Molecular mechanisms behind mitochondrial dysfunction in chronic heart failure

Chronic heart failure induces dysfunction in the cell’s powerhouses, which is caused in part by an excess of an essential intermediate compound in energy production. Compensating for this by supplementing the diet could be a potential technique for treating heart failure.

26 Oct 2022

Bacteria do engage in photosynthesis, research suggests

Knowing whether or not marine microbes engage in photosynthesis -; the use of sunlight to turn carbon dioxide and water into energy -; could help scientists to learn if ocean bacteria play a role in the global carbon cycle.

25 Oct 2022

Key to developing more effective obesity treatments

The amygdala, a part of the brain, is in charge of strong emotions such as fear. Scientists have shown that the amygdala may be at fault for overeating.

25 Oct 2022

Conserved vacuolar sorting hub regulates autophagic flux in plants

A “hub and spoke” system allows plant cells to effectively coordinate cellular trafficking, especially for cellular recycling, also known as autophagy. Autophagosomes are specialized vesicles that capture hazardous molecules and transport them to the vacuole, where they are destroyed.

21 Oct 2022

Applying machine learning to define significant immune cells

The method correctly categorizes macrophage states, which is crucial since these cells can alter their behavior and function as either pro- or anti-inflammatory agents during an immune response.

20 Oct 2022

New consortium for scaled up meat produced from cultivated cells

Competition promotes innovation, but for a nascent industry, one strategy is for competitors to band together to tackle fundamental technical obstacles, set standards, and exchange knowledge in a way that benefits the industry as a whole.

20 Oct 2022

Novel method for comparing single-cell trajectories with tree alignment

The genes that are activated in a single cell can now be determined thanks to advances in high-throughput biological studies. However, interpreting the resulting complex datasets might be difficult.

From Osaka University 20 Oct 2022

The ability of cells to adjust their growth to changing environmental conditions

Growth is a fundamental element of all life on this planet, whether it be a mammal, a single-celled organism, a plankton, or a sequoia.

18 Oct 2022

The influence of fatty acid metabolism on plant immunity

Most people do not realize that fatty acids can be found in a nutritious salad. Although fatty acids, lipids, and fats may seem unappealing, they are essential to human life and to the plants that are consumed.

17 Oct 2022

Molecular insights into the photosynthesis process

The most essential foundation of life on Earth is photosynthesis. Plants and single-celled algae use sunlight’s energy to turn it into sugar and biomass.

17 Oct 2022

Brain-resident and recruited macrophages exhibit diverging responses

Prof. Kiavash Movahedi (VUB, VIB) headed a group that outlined how the immune system responds to infections entering the brain. The results offer new information on host-pathogen interactions as well as the long-term effects of brain infections.

14 Oct 2022

Nonconducting W434F mutant varies in structure and conformation

Potassium (K+) channels are tiny, highly specialized conduits found in every live cell that transfer K+ ions in an exceedingly selective and quick manner across cell membranes.

13 Oct 2022

Building designer plant cuticles with important protective functions

Scientists are working to bioengineer a common defense mechanism that most plants develop naturally to protect against drought, insects and other environmental stresses.

11 Oct 2022

A remarkable finding reorients attempts to cure liver disease

A long-running debate in gastroenterology has been settled by WEHI researchers who have shown that prevalent liver diseases are not caused by inflammatory cell death as previously believed.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 7 Oct 2022