Cell Biology

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The Art of Neuroscience: Synaptic Transmission and Plasticity in Isolated Neurons

Studying the complex interactions between synaptic nerve endings as well as their development has now become much easier.

30 Aug 2023

T Cells Infiltrate Brain and Worsen Alzheimer's Pathology, Study Finds

Cognitive decline associated with Alzheimer's disease (AD) develops when neurons begin to die, which can be caused by inappropriate immune responses and excessive inflammation in the brain triggered by amyloid beta deposits and tau tangles, two hallmarks of the disease.

28 Aug 2023

NSL Complex Regulates Intraciliary Transport Genes in Multiple Cell Types

The non-specific lethal (NSL) complex is a chromatin-associated factor that has been shown in both fruit flies and mammals to regulate the expression of thousands of genes. Abrogation of the NSL genes causes the organism to die, which gives rise to the complex’s unusual name.

28 Aug 2023

Gene Therapy Shows Promise for Muscular Dystrophy Patients

Researchers at Cincinnati Children’s Hospital reveal how damage to the cell’s energy factory causes muscle wasting. Closing a pore in the mitochondrial membrane in gene-edited mice prevents disease progression.

28 Aug 2023

Age-Related Hearing Loss Associated With Decrease of Cholesterol in the Inner Ear

Researchers led by María Eugenia Gomez-Casati, the Institute of Pharmacology, School of Medicine, University of Buenos Aires-CONICET; Mauricio Martin, the Institute of Medical Research Mercedes; and Martín Ferreyra, (INIMEC-CONICET-UNC), National University of Córdoba in Argentina report that age-related hearing loss is associated with a decrease of cholesterol in the inner ear.

25 Aug 2023

Researchers Shed Light on Complex Interplay Between Taste Perception and Immune Function

A bitter taste in the mouth is often a symptom or side effect of illness, which may be the result of how the body reacts to pathogens. A new study published in iScience, by Hong Wang, PhD, an Associate Member at the Monell Chemical Sense Center, and colleagues sheds light on the mechanisms involved in the complex interplay between taste perception and immune function.

25 Aug 2023

Study Shows How Genomic Topography Influences Where Cancer Mutations Arise

Researchers at the University of California San Diego have uncovered a connection between the topography of the human genome and the presence of mutations in human cancer. They found that certain regions of the genome, which exhibit unique features, act as hotspots for the accumulation of mutations.

25 Aug 2023

Scientists Uncover New Mechanism for Degrading Short-Lived Proteins

Short-lived proteins control gene expression in cells to carry out a number of vital tasks, from helping the brain form connections to helping the body mount an immune defense. These proteins are made in the nucleus and are quickly destroyed once they've done their job.

25 Aug 2023

Bioengineered Enzyme-Based Scissors can Selectively Remove Mucins Off Cancer Cells

Cancer cells can evade the body's immune defenses by exploiting a normally helpful and ubiquitous group of molecules known as mucins.

24 Aug 2023

A Newly Discovered Plant Gene that Helps Make Apiin: The Search Ends Here

Apiin, a natural compound found in high amounts in parsley and celery, is thought to have important medicinal properties.

24 Aug 2023

Researchers Gain Insights Into Brain's Voluntary Mechanisms

Picture this scenario: You and a friend are walking around your neighborhood when you stop at a crosswalk. As you wait, the noises of the world and your internal thoughts all vie for your attention. Suddenly, you see a motorist nearly hit a bicyclist.

24 Aug 2023

Innovative Method Accelerates Discovery of New Drugs by Harnessing the Power of Ribosomes

A research team led by University of California, Irvine scientists has developed an innovative method for quickly and efficiently creating vast collections of chemical compounds used in drug discovery by harnessing the power of ribosomes, the molecules found in all cells that synthesize proteins and peptides.

24 Aug 2023

Sensory Neurons Develop Customized Nerve Endings Based on Cues From the Skin, Finds Study

Nerve cells that sense touch grow the appropriate endings for hairy or hairless skin based on cues from the skin itself, rather than through predetermined programming, according to research led by Harvard Medical School scientists and published Aug. 21 in Developmental Cell.

23 Aug 2023

New Cell Type Related to Organ Movement for Plant Selfing

Dr Yin-Zheng Wang of the Chinese Academy of Sciences' Institute of Botany is the lead of the study team that discovered movement in the Chirita pumila stigma and established a link between the motion and water sensitivity.

23 Aug 2023

Scientists Develop New Method to Control Insulin Release with Music

Diabetes is a condition in which the body produces too little or no insulin. Diabetics thus depend on an external supply of this hormone via injection or pump. Researchers led by Martin Fussenegger from the Department of Biosystems Science and Engineering at ETH Zurich in Basel want to make the lives of these people easier and are looking for solutions to produce and administer insulin directly in the body.

23 Aug 2023

Cell Biology

The Art of Neuroscience: Synaptic Transmission and Plasticity in Isolated Neurons

T Cells Infiltrate Brain and Worsen Alzheimer's Pathology, Study Finds

NSL Complex Regulates Intraciliary Transport Genes in Multiple Cell Types

Gene Therapy Shows Promise for Muscular Dystrophy Patients

Age-Related Hearing Loss Associated With Decrease of Cholesterol in the Inner Ear

Researchers Shed Light on Complex Interplay Between Taste Perception and Immune Function

Study Shows How Genomic Topography Influences Where Cancer Mutations Arise

Scientists Uncover New Mechanism for Degrading Short-Lived Proteins

Bioengineered Enzyme-Based Scissors can Selectively Remove Mucins Off Cancer Cells

A Newly Discovered Plant Gene that Helps Make Apiin: The Search Ends Here

Researchers Gain Insights Into Brain's Voluntary Mechanisms

Innovative Method Accelerates Discovery of New Drugs by Harnessing the Power of Ribosomes

Sensory Neurons Develop Customized Nerve Endings Based on Cues From the Skin, Finds Study

New Cell Type Related to Organ Movement for Plant Selfing

Scientists Develop New Method to Control Insulin Release with Music

Study Solves Mystery and Establish the Mechanism Underlying SLC29A3 Disorders

Analyzing the First Vaccine Against Respiratory Syncytial Virus in Many Older Adults

Global Map of How the Animal’s Nervous System is Organized to Control Behavior

New Synthetic Catalyst Breaks Down Cellulose: Study

Noelin1-3 Proteins Have Major Influence on Learning and Memory Formation in the Mammalian Brain

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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