Cell Biology

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New technique enables researchers to pinpoint protein–drug interaction

The discovery and development of new drugs may be facilitated by the use of a novel method that can analyze the interactions of drug molecules with proteins in tissue samples. In cooperation with the major biopharmaceutical company AstraZeneca, University of Birmingham researchers created the method.

15 Jul 2022

New research shows how stem cells act in the intestine

The use of stem cells in medical therapy is a hot issue. Scientists are still unsure of how cells decide to divide or differentiate in order to regenerate organs. Recently, scientists discovered a new biophysical mechanism that controls stem cells in mice’s intestines.

14 Jul 2022

Researchers identify the molecular route that leads to autoimmune disease inflammation

Mitochondria are self-contained organelles that reside inside cells and are tasked with producing the chemical energy required to power vital tasks necessary for life and wellbeing. They have their own mini-chromosome and DNA.

From UC San Diego 14 Jul 2022

Researchers discover cancer cells move to sweet spot conditions, likely to enable stronger traction

Cancer cells can be drawn to certain mechanical “sweet spot” conditions, according to a global team of researchers headed by University of Minnesota Twin Cities engineers.

14 Jul 2022

Researchers create novel human cell line to explore blinding eye disorders

Researchers at the LSU Health New Orleans Neuroscience Center of Excellence have created a novel, experimental human cell line from retinal pigment epithelial cells, under the supervision of Boyd Professor Nicolas Bazan, MD, PhD.

14 Jul 2022

Researchers discover the atomic structure of the nuclear pore complex

Nearly 100 trillion cells make up the human body, which is what keeps people healthy and alive. The mechanisms of life are maintained by the billions of pieces that each cell has on its own.

14 Jul 2022

Researchers develop first biohybrid model of human ventricles with helically aligned beating cardiac cells

Heart disease -; the leading cause of death in the U.S. -; is so deadly in part because the heart, unlike other organs, cannot repair itself after injury.

11 Jul 2022

Challenges in Drug Discovery; Where are we now, and where are we going?

As part of our SLAS Europe 2022 coverage, we speak to Steve Rees, Vice-President of Discovery Biology at AstraZeneca, about the challenges currently faced by the drug discovery sector.

From Society for Laboratory Automation and Screening (SLAS) 8 Jul 2022

Researchers investigate dynamics and modifications of COVID-19 virus spike protein

When the coronavirus that causes COVID-19 infects human cells, the cell’s protein-processing machinery modifies the spike protein, making it more flexible and mobile, potentially increasing its possibility to contaminate other cells and evade antibodies, according to new research from the University of Illinois Urbana-Champaign.

8 Jul 2022

How can High-Content Screening accelerate Drug Discovery?

As part of our SLAS Europe 2022 coverage, we speak to Professor Jeremy Simpson from the University College Dublin about the role high-content screening can play in accelerating drug discovery.

From Society for Laboratory Automation and Screening (SLAS) 6 Jul 2022

Scientists link the function of specific domain of proteins to a cancer trigger in humans

Researchers at the Department of Energy's Oak Ridge National Laboratory have definitively linked the function of a specific domain of proteins important in plant-microbe biology to a cancer trigger in humans, knowledge that had eluded scientists for decades.

6 Jul 2022

Research reveals how two RNA-binding proteins interact with each other

Neurons are continually adapting to changing conditions. The biochemical basis for memory and learning is this plasticity.

5 Jul 2022

Researchers analyze the significance of cellular interactions for lung cancer

A new Cleveland Clinic study has uncovered vital information about the cellular interaction of tumor cells and normal tissue, leading to a better understanding of how therapeutic resistance evolves.

5 Jul 2022

A new technique eases identification of cell-type-specific genes in single-cell data

A biological sample contains thousands of unique cells that may all be examined separately and individually, cell by cell.

From The Max Planck Institute 5 Jul 2022

Study deciphers the mechanisms of bacterial host cell adhesion

To create a new class of antibiotics, investigators from University Hospital Frankfurt and Goethe University Frankfurt have figured out how bacteria adhere to host cells.

4 Jul 2022

Study shows how mitochondrial RNA changes enhance invasive growth of cancer cells

The energy centers of cells and mitochondria have their own genetic material and RNA molecules.

1 Jul 2022

Researchers understand the processes that affect the efficiency of the CRISPR method

When it comes to the ability of genetic engineering, the only restriction is the human imagination, particularly since the discovery of CRISPR technology.

1 Jul 2022

Giving attention to beta cells instead of the immune system could be a chance to prevent type 1 diabetes

Research studying the autoimmune response, in which the immune system kills the insulin-producing pancreatic islet beta cells, is a common topic of type 1 diabetes research.

1 Jul 2022

Easy determination method for the electrical penetration of cell membrane

To analyze individual cells with unprecedented precision, biologists in particular use highly specialized methods and cutting-edge technology.

1 Jul 2022

Researchers create new wheat–rye addition lines that impart Ug99 resistance

Dr Fangpu Han’s team from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences has recently reported the development of novel wheat-rye addition lines that imparted resistance to Ug99 in a work that was published online in Theoretical and Applied Genetics.

27 Jun 2022

Cell Biology

New technique enables researchers to pinpoint protein–drug interaction

New research shows how stem cells act in the intestine

Researchers identify the molecular route that leads to autoimmune disease inflammation

Researchers discover cancer cells move to sweet spot conditions, likely to enable stronger traction

Researchers create novel human cell line to explore blinding eye disorders

Researchers discover the atomic structure of the nuclear pore complex

Researchers develop first biohybrid model of human ventricles with helically aligned beating cardiac cells

Challenges in Drug Discovery; Where are we now, and where are we going?

Researchers investigate dynamics and modifications of COVID-19 virus spike protein

How can High-Content Screening accelerate Drug Discovery?

Scientists link the function of specific domain of proteins to a cancer trigger in humans

Research reveals how two RNA-binding proteins interact with each other

Researchers analyze the significance of cellular interactions for lung cancer

A new technique eases identification of cell-type-specific genes in single-cell data

Study deciphers the mechanisms of bacterial host cell adhesion

Study shows how mitochondrial RNA changes enhance invasive growth of cancer cells

Researchers understand the processes that affect the efficiency of the CRISPR method

Giving attention to beta cells instead of the immune system could be a chance to prevent type 1 diabetes

Easy determination method for the electrical penetration of cell membrane

Researchers create new wheat–rye addition lines that impart Ug99 resistance

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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